SPARC Induced Tendon Differentiation And Regeneration
Funder
National Health and Medical Research Council
Funding Amount
$154,718.00
Summary
Tendinopathy has a significant patient morbidity, which is a clear burden to the Australian economy. A better fundamental grasp of tendon tissue biology is urgently required. This study will enable us to establish the role of matricellular protein SPARC in tendon function, thus enhance the understanding of tendon biology and enable translation of the bench work to potential clinical applications.
As many as 50% of patients having surgery take medications unrelated to their surgery and up to 46% of patients have their medications stopped at surgery. Patients who take regular medications unrelated to their surgery are 2.7 times more at risk of complications post surgery than those who do not take medications. As time without regular medication increase, so do the post surgery complication rate. This project aims to improve the use of patientsÍ regular medications at the time of surgery.