Preventing Anxiety, Depression And Substance Use In Adolescents.
Funder
National Health and Medical Research Council
Funding Amount
$1,709,988.00
Summary
Anxiety, depressive and substance use disorders account for three quarters of the disability attributed to mental disorders. Yet we have few models of well-implemented prevention programs for these common disorders. The current proposal addresses this gap by evaluating an innovative internet-based approach to preventing mental health and substance use problems in Australian adolescents.
Centre Of Research Excellence In Medicines Intelligence
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
The NHMRC Centre of Research Excellence in Medicines Intelligence is a co-ordinated research program that will accelerate the development and translation of evidence on prescribed medicines use and outcomes for regulators and payers. The CRE is perfectly placed to embrace the national ‘call to action’ from the Health Minister's recent announcement to establish Quality Use of Medicine Safety as a National Health Priority.
Indigenous Mental Health Model Of Care: RCT Based On A Trans-diagnostic CBT Program Co-designed With Community
Funder
National Health and Medical Research Council
Funding Amount
$996,217.00
Summary
We propose to develop an Indigenous Model of Mental Health Care (IMMHC) that encompasses psychological therapy and cultural healing practices developed in consultation with local, participating Indigenous communities, that will for the first time treat highly prevalent mood and anxiety disorders in Indigenous Australians.
Use Of Molecular Resistance Assays To Provide Alterative Oral Treatment Strategies For Gonorrhoea In Indigenous And Other High-risk Populations; A Randomised Cluster Trial
Funder
National Health and Medical Research Council
Funding Amount
$828,671.00
Summary
Gonorrhoea has now developed resistance to almost all antibiotics that have been used to treat it. In this study, we will investigate a new treatment approach that selects antibiotics on a patient-by-patient basis. We will use new molecular assays to first test if a gonorrhoea strain infecting a patient is susceptible to an antibiotic, and will then treat on the basis of this result. By doing so, we will optimize our use of antibiotics and improve treatment strategies for gonorrhea.
Transitions of mobility and parking. Transitions of mobility and parking. This project aims to understand the role of parking in mobility, urban consolidation and transit-oriented development. Does parking supply affect travel demand, car ownership, and ultimately urban quality of life? New transitions and trends in land-use and transport, including car-sharing and automated vehicles, and the revival of urban living, raise important questions about the redesign and reuse of urban space. This pro ....Transitions of mobility and parking. Transitions of mobility and parking. This project aims to understand the role of parking in mobility, urban consolidation and transit-oriented development. Does parking supply affect travel demand, car ownership, and ultimately urban quality of life? New transitions and trends in land-use and transport, including car-sharing and automated vehicles, and the revival of urban living, raise important questions about the redesign and reuse of urban space. This project aims to give policy-makers an evidence base and toolkit to determine how best to repurpose the space currently accommodating private cars. This project is expected to make cities more attractive, efficient and liveable, improving a disproportionately large number of Australian lives.Read moreRead less
Who You Know or Where You Go? The Role of Formal and Informal Networks in Finding Employment and Maintaining Wellbeing. Recent empirical studies have demonstrated that informal social networks improve well-being and labour market outcomes for the unemployed in Europe. However, no comparable Australian study has been conducted and there is little research on the role of the 'formal' networks represented by employment services programs in Australia or overseas. This project aims to explore unemplo ....Who You Know or Where You Go? The Role of Formal and Informal Networks in Finding Employment and Maintaining Wellbeing. Recent empirical studies have demonstrated that informal social networks improve well-being and labour market outcomes for the unemployed in Europe. However, no comparable Australian study has been conducted and there is little research on the role of the 'formal' networks represented by employment services programs in Australia or overseas. This project aims to explore unemployed people's formal and informal networks and the impact of those networks on employment status and wellbeing. This project aims to inform unemployment policy design and service delivery by providing a greater understanding of the role that social networks play in finding jobs and surviving unemployment.Read moreRead less
The effect of wastewater treatment on the ecotoxicity of chiral chemicals. This project aims to assess the environmental implications of pharmaceuticals discharged in effluents from wastewater treatment plants. Trace levels of human pharmaceuticals occur in sewage and urban waterways, but during sewage treatment, some pharmaceuticals can undergo a chemical transformation known as 'chiral inversion'. In some cases, this may convert relatively benign environmental contaminants to more ecologically ....The effect of wastewater treatment on the ecotoxicity of chiral chemicals. This project aims to assess the environmental implications of pharmaceuticals discharged in effluents from wastewater treatment plants. Trace levels of human pharmaceuticals occur in sewage and urban waterways, but during sewage treatment, some pharmaceuticals can undergo a chemical transformation known as 'chiral inversion'. In some cases, this may convert relatively benign environmental contaminants to more ecologically toxic species. This project will investigate why and how some pharmaceuticals become susceptible to chiral inversion and assess ecotoxicological differences. This work is expected to determine the significance of considering chiral inversion in environmental risk assessment, with applications to a broader range of chemicals including pesticides and industrial chemicals.Read moreRead less
Pro bono service: drivers, delight, dark side and downside for the professional. Pro bono work, common in the professions, is important to Australia's economy. This ground breaking research provides rich insights into why pro bono givers feel unappreciated, unacknowledged, unreciprocated, and often taken advantage of and, importantly, equips professionals with strategies for enhanced outcomes.
Pharmacology Of Potential Anti-Tumour Agents: Iron Chelators Of The BpT Class
Funder
National Health and Medical Research Council
Funding Amount
$585,455.00
Summary
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class Cancer cells have a high iron requirement for DNA synthesis and many clinical trials showed Fe chelators are effective anti-cancer drugs. Their potential to act as anti-tumour agents has been confirmed by the entrance of Triapine into widespread NCI clinical trials. In this NHMRC Renewal, we will perform pharmacological and preclinical studies to promote the development of BpT chelators as novel anti-tumour agents.