ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environme ....ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environments. EII will address 3 tightly coupled research themes: Ability to interoperate across existing heterogenous platforms & applications; Efficient processing of very large data sets; Technology adoption & impact. Generic results will be applicable to e-science and large business information systems installations.Read moreRead less
Practice-based Systematized Nomenclature of Medicine (SNOMED) concept learning for drug-disease precaution early detection and refinement. The outcome of the Systematized Nomenclature of Medicine (SNOMED) concept learning system will help mitigate the impact of Adverse Drug Events hence directly contribute to the National Research Priority promoting and maintaining good health. It will tailor SNOMED knowledge to different clinical settings and provide evidence-based preventative health care. Th ....Practice-based Systematized Nomenclature of Medicine (SNOMED) concept learning for drug-disease precaution early detection and refinement. The outcome of the Systematized Nomenclature of Medicine (SNOMED) concept learning system will help mitigate the impact of Adverse Drug Events hence directly contribute to the National Research Priority promoting and maintaining good health. It will tailor SNOMED knowledge to different clinical settings and provide evidence-based preventative health care. The enabling methodology from this project for building computerised cognitive learning systems will be a frontier technology to enhance smart information use in clinical decision support. It will also contribute to the development of knowledge-based systems. A network version of the developed system will assist doctors working in rural and remote areas with their clinical decision making and prescribing practice.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883073
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
BigNet - A Distributed Wireless Sensor Network Testbed. The infrastructure developed will be of national /international significance, given the rapid emergence of wireless sensor networks. This integrated facility will allow Australia to be a world leading player in the research and technology development as well as the socially responsible deployment of sensor networks. The facility has the explicit aim to ensure that Australia is a technology leader rather than solely a technology user in sens ....BigNet - A Distributed Wireless Sensor Network Testbed. The infrastructure developed will be of national /international significance, given the rapid emergence of wireless sensor networks. This integrated facility will allow Australia to be a world leading player in the research and technology development as well as the socially responsible deployment of sensor networks. The facility has the explicit aim to ensure that Australia is a technology leader rather than solely a technology user in sensor networks. The test facility will mirror practical requirements for WSN implementation in the Great Barrier Reef and in timber plantation, which would offer substantial economic benefits to Australia.Read moreRead less
Characterisation Of Eurl, A Novel Gene Implicated In The Etiology Of Abnormal Brain Development And Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$597,541.00
Summary
Intellectual disability affects around one per cent of Australians, and can arise from genetic abnormalities during fetal life, such as through abnormal regulation of gene expression. We have identified a novel gene, known as eurl, which controls brain assembly as well as the ability of neurons to form functional connections within the brain. We will investigate how this novel gene controls brain development, and characterise eurl as a potential therapeutic target for learning and memory.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0667981
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Kangaroo Genome Resource Management Facility. Increasingly, large Australian multicentre research programs in biological and medical sciences have a genomics component that involves integration of biological information with sequencing data. The success of these research programs depends on rapid internet access to the research information by all participating scientists. The universal design of the proposed information management system means that it can be easily adapted to support a broad ran ....Kangaroo Genome Resource Management Facility. Increasingly, large Australian multicentre research programs in biological and medical sciences have a genomics component that involves integration of biological information with sequencing data. The success of these research programs depends on rapid internet access to the research information by all participating scientists. The universal design of the proposed information management system means that it can be easily adapted to support a broad range of research programs. The development of this software program therefore has the potential to benefit research scientists, academics and students in many related fields, as well as the broader community, through enhancing research outcomes.Read moreRead less
ARC Centre for Perceptive & Intelligent Machines in Complex Environments. The Centre for Perceptive and Intelligent Machines in Complex Environments will perform fundamental research into and construct reliable large-scale systems of networked sensors, computational intelligence, mobile robots, and knowledge sources to support a large variety of critical human tasks, including surveillance/ security (eg. borders/airports/homes), health care support (eg. smart houses/ health condition monitoring, ....ARC Centre for Perceptive & Intelligent Machines in Complex Environments. The Centre for Perceptive and Intelligent Machines in Complex Environments will perform fundamental research into and construct reliable large-scale systems of networked sensors, computational intelligence, mobile robots, and knowledge sources to support a large variety of critical human tasks, including surveillance/ security (eg. borders/airports/homes), health care support (eg. smart houses/ health condition monitoring, semi autonomous wheelchairs), and civil disaster support (eg. fighting bushfires, looking for people in rubble) always keeping people in the loop so that strong human/ machine cooperative ventures can achieve what neither human or machines could accomplish independently.Read moreRead less
Developing Reliable Bio-Crypto Features for Mobile Template Protection. Cost of identity theft crimes were at multi-million dollars in Australia in 2007. Technically this is due to the fact that conventional personal identification number and token based security mechanisms cannot identify genuine users. Biometric fingerprint security systems emerge as a promising solution. However protection of the mobile embedded fingerprint template itself is an unresolved problem. The project aims to devel ....Developing Reliable Bio-Crypto Features for Mobile Template Protection. Cost of identity theft crimes were at multi-million dollars in Australia in 2007. Technically this is due to the fact that conventional personal identification number and token based security mechanisms cannot identify genuine users. Biometric fingerprint security systems emerge as a promising solution. However protection of the mobile embedded fingerprint template itself is an unresolved problem. The project aims to develop new ways designing bio-cryptosystems that provide strong security strength. The project will bring new body of knowledge into this field and place Australia in the forefront of this research, and also result in strengthened security of IT infrastructure and systems for industries.Read moreRead less
The critical role of kisspeptin/neurokinin/dynorphin (KNDy) neurons in gonadotropin releasing hormone (GnRH) release. The brain controls fertility through the secretion of its primary stimulatory factor, gonadotropin releasing hormone (GnRH). Brain cells producing three key peptide hormones, kisspeptin, neurokin B and dynorphin (termed KNDy cells) are vital for the control of GnRH. This project will detail the role of KNDy cells in puberty and reproduction.
Subcellular recruitment of a RhoA ubiquitination complex by Rnd proteins. This study addresses a novel molecular mechanism through which members of the Rnd family of GTP-binding proteins regulate the morphology and migration of immature nerve cells of the developing nervous system. This study has broad implications for the understanding of cell migration during embryo development, as well as in health and disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561030
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiative ....Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiatives in developmental and cellular biology. This large-scale, high-resolution expression profiling infrastructure is required to maintain international competitiveness and will dramatically improve our gene discovery, functional assessment and understanding of vertebrate development.Read moreRead less