Improving Treatment Strategies For Chronic Alphaviral Arthritic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$643,624.00
Summary
Chikungunya virus and Ross River virus cause epidemics of acute and chronic arthritic disease in humans, which is often poorly managed with current treatments. This grant seeks to understand the mechanisms that give rise to disease in order to identify improved treatment strategies. Both the persistence of viral replication in joint tissues and unnecessary inflammatory responses appear to be important factors driving chronic disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100192
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
Deep Protein Sequencing, Structure and Quantification Facility. This project aims to establish state-of-the-art complementary mass spectrometers to help research into molecular structure and interactions, post-translational modifications, compound stability and availability within complex biological samples. The facility’s complementary mass spectrometers combine high specificity with high sensitivity and ultrafast scanning, and are expected to rapidly discover, identify and characterise biomole ....Deep Protein Sequencing, Structure and Quantification Facility. This project aims to establish state-of-the-art complementary mass spectrometers to help research into molecular structure and interactions, post-translational modifications, compound stability and availability within complex biological samples. The facility’s complementary mass spectrometers combine high specificity with high sensitivity and ultrafast scanning, and are expected to rapidly discover, identify and characterise biomolecules including peptides, proteins and small molecules. The discovery of unknown compounds is expected to improve fundamental understanding of molecular structure and function, provide opportunities for new bio-industries in health and the environment, and generate commercial opportunities through spin-off companies, patents and licensing.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100050
Funder
Australian Research Council
Funding Amount
$1,681,491.00
Summary
A national network for magnetic resonance spectroscopy. Our proposed network of high-end facilities for solid-state nuclear magnetic resonance spectroscopy aims to establish cutting-edge capabilities nationally for molecular and materials characterisation. The new infrastructure will enable advanced studies in chemistry, drug design, materials science, and environmental sciences. The expected outcomes include new discoveries, innovative applications, and potential commercialisation of new produc ....A national network for magnetic resonance spectroscopy. Our proposed network of high-end facilities for solid-state nuclear magnetic resonance spectroscopy aims to establish cutting-edge capabilities nationally for molecular and materials characterisation. The new infrastructure will enable advanced studies in chemistry, drug design, materials science, and environmental sciences. The expected outcomes include new discoveries, innovative applications, and potential commercialisation of new products, which will bring significant economic benefits to the Australian economy. Additionally, the network will foster collaborations with international researchers and industry partners in areas of biotechnology, energy capture and storage, and environmental sustainability.Read moreRead less
Defining the Brassica pan-genome and establishing methods for gene conversion based crop improvement. Gene content varies between individual varieties. The project aims to apply novel genomic tools to identify and characterise the fixed and variable gene content in the important crop canola and use this to understand genome evolution as well as develop tools to accelerate canola breeding. The project team have developed and used a high-resolution genotyping approach to demonstrate that gene conv ....Defining the Brassica pan-genome and establishing methods for gene conversion based crop improvement. Gene content varies between individual varieties. The project aims to apply novel genomic tools to identify and characterise the fixed and variable gene content in the important crop canola and use this to understand genome evolution as well as develop tools to accelerate canola breeding. The project team have developed and used a high-resolution genotyping approach to demonstrate that gene conversions, short recombination events which lead to the non-reciprocal exchange of genomic regions during meiosis, are abundant in crop genomes. The project aims to develop methods and resources to characterise gene conversion in canola and establish a basis for gene conversion based crop improvement.Read moreRead less
Special Research Initiatives - Grant ID: SR200200003
Funder
Australian Research Council
Funding Amount
$227,131.00
Summary
The evolution of disability arts in Australia. This project aims to create the first archive documenting, analysing and theorising disability arts in Australia. Australian disability arts is recognised globally for its innovation and impact. However, the historical legacy this celebrated contemporary work builds on is largely undocumented. This project aims to address this gap by studying archival records, conducting oral history interviews, and then co-designing a disability arts archive with a ....The evolution of disability arts in Australia. This project aims to create the first archive documenting, analysing and theorising disability arts in Australia. Australian disability arts is recognised globally for its innovation and impact. However, the historical legacy this celebrated contemporary work builds on is largely undocumented. This project aims to address this gap by studying archival records, conducting oral history interviews, and then co-designing a disability arts archive with artists and other stakeholders. It should benefit scholars, arts organisations, artists and government by creating a comprehensive, curated, culturally respectful record to inform present and future policy initiatives designed to make the arts industry more inclusive of people with disabilities. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100021
Funder
Australian Research Council
Funding Amount
$2,168,000.00
Summary
Australian Metabolic Phenotyping Centre (AMPC). This project aims to establish a centre for targeted and exploratory metabolic phenotyping. Metabolic phenotyping quantitatively measures the precursors, intermediates and products of metabolism interacting within a biological system. This project will use high-resolution spectrometry and spectroscopy to generate comprehensive, multi-parameter metabolite data sets for biological samples at the population level, at unprecedented throughput and low c ....Australian Metabolic Phenotyping Centre (AMPC). This project aims to establish a centre for targeted and exploratory metabolic phenotyping. Metabolic phenotyping quantitatively measures the precursors, intermediates and products of metabolism interacting within a biological system. This project will use high-resolution spectrometry and spectroscopy to generate comprehensive, multi-parameter metabolite data sets for biological samples at the population level, at unprecedented throughput and low cost, to address biological and biomedical research needs. This project is expected to make Australian scientists globally competitive in the life sciences including biological, clinical and biomedical, plant and crop sciences, analytical chemistry, toxicology, agriculture, wildlife conservation and sports science, and to drive advances in the data sciences for systems biology.Read moreRead less
The deep history of Sea Country: Climate, sea level and culture. This project aims to investigate the records of the now-submerged Pilbara coast (50,000 to 7000 years ago). Nearly a third of Australia’s landmass was drowned after the last ice age, and sea-level change displaced generations of people. Submerged landscape archaeology will help reveal past sea-level rise, population resilience, mobility and diet. The project integrates cultural and environmental studies and material analysis, and a ....The deep history of Sea Country: Climate, sea level and culture. This project aims to investigate the records of the now-submerged Pilbara coast (50,000 to 7000 years ago). Nearly a third of Australia’s landmass was drowned after the last ice age, and sea-level change displaced generations of people. Submerged landscape archaeology will help reveal past sea-level rise, population resilience, mobility and diet. The project integrates cultural and environmental studies and material analysis, and adapts a method from the world’s only confirmed submarine middens. It will use marine and aerial survey techniques to investigate physical and cultural submerged landscapes. This project expects to influence heritage and environmental management and the marine heritage sector.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100124
Funder
Australian Research Council
Funding Amount
$538,590.00
Summary
An Advanced Ultrafast Laser Spectroscopy Facility in Queensland. The project aims to establish a world-class ultrafast laser spectroscopy facility to investigate how molecules interact with visible or ultraviolet light. Light-matter interactions are key to energy generation in nature through photosynthesis as well as everyday technologies including optical communications and displays. This project expects to generate new knowledge in on how light interacts with matter at the molecular level. Exp ....An Advanced Ultrafast Laser Spectroscopy Facility in Queensland. The project aims to establish a world-class ultrafast laser spectroscopy facility to investigate how molecules interact with visible or ultraviolet light. Light-matter interactions are key to energy generation in nature through photosynthesis as well as everyday technologies including optical communications and displays. This project expects to generate new knowledge in on how light interacts with matter at the molecular level. Expected outcomes of the ultrafast spectroscopic measurements will be understanding the fate of light absorbed by or generated in different materials. Application of the knowledge gained will enable the design of materials for more efficient technologies such as solar cells, lighting, and sensors.Read moreRead less
Willing collaborators: Negotiating Change in East Asian Media Production. This project examines how media producers and investors from China, Korea, Taiwan, and Hong Kong are moving into flexible and innovative forms of collaboration. Focusing on cinema, television, online video and mobile content in East Asia, the study enhances academic, industry and policy understandings of the dynamics of regional media production. In addition, the project investigates opportunities and challenges for Austra ....Willing collaborators: Negotiating Change in East Asian Media Production. This project examines how media producers and investors from China, Korea, Taiwan, and Hong Kong are moving into flexible and innovative forms of collaboration. Focusing on cinema, television, online video and mobile content in East Asia, the study enhances academic, industry and policy understandings of the dynamics of regional media production. In addition, the project investigates opportunities and challenges for Australian and other international media companies. It addresses the urgent need to foster understanding of the media industries and cultures of Australia's regional neighbours in order to better equip the nation and its screen sectors to participate in the forthcoming "Asian Century". Read moreRead less