Centre For Clinical Research Execllence In Infectous Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
The Centre will enhance Australia's capacity in patient oriented research in infectious disease, building on the strengths of the Victorian Infectious Diseases Service for improvement of patient outcomes and betterment of human health. They will strengthen programs in clinical virology, infections in immunocompromised hosts, infections of travellers and immigrants, computer assisted decision making and will fill an important gap in training and mentoring physicians for clinical research.
The Centre will enhance Australian clinical immunisation research and training, focussing upon clinical questions with translatable outcomes not easily addressed by industry. Optimal immunisation and interventions to maximise uptake of existing and new vaccines in high risk patient groups, such as children with cancer, immigrants, children with chronic diseases and adolescents will be studied. New vaccine trials, innovative use of existing vaccines, systematic collection of vaccine failure data, ....The Centre will enhance Australian clinical immunisation research and training, focussing upon clinical questions with translatable outcomes not easily addressed by industry. Optimal immunisation and interventions to maximise uptake of existing and new vaccines in high risk patient groups, such as children with cancer, immigrants, children with chronic diseases and adolescents will be studied. New vaccine trials, innovative use of existing vaccines, systematic collection of vaccine failure data, and targeted epidemiology and disease modelling vaccine preventable disease will also allow a broad program of research, enabling training and mentoring of young clinical nurse and physician researchers. Collaborations with existing national immunisation, infectious diseases and research institutions will allow maximal effectiveness of clinical studies.Read moreRead less
Interdisciplinary Clinical And Health Ethic Research And Training To Improve Outcomes In Immunosuppressed Haematology Pa
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
The Centre will improve Australia's capacity to combat and prevent life-threatening infections, and reduce adverse social outcomes, in high-risk children and adults with heavily suppressed immune systems. Infections cause most preventable disease and death in these patients. We will establish multidisciplinary training programmes in clinical and ethics research and build on our expertise in infectious diseases and microbiology, diagnostics, haematology, immunisation, health informatics and bioet ....The Centre will improve Australia's capacity to combat and prevent life-threatening infections, and reduce adverse social outcomes, in high-risk children and adults with heavily suppressed immune systems. Infections cause most preventable disease and death in these patients. We will establish multidisciplinary training programmes in clinical and ethics research and build on our expertise in infectious diseases and microbiology, diagnostics, haematology, immunisation, health informatics and bioethics to improve patient outcomes. These outcomes will be translatable to other high-risk patients such as those with cancer and the critically ill.Read moreRead less
Centre For Training In Clinical Cardiovascular And Cerebrovascular Research
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
This Centre proposes to expand its highly successful Centre of Clinical Excellence funded by NHMRC from 1998-2001. The Centre provided the opportunity in Western Australia for the highest quality clinical research training in comprehensive spheres relevant to the pathogenesis, prevention and therapeutics of cardiovascular disease, with an emphasis on the role of nutrition and lifestyle in relation to high blood pressure, arteriosclerosis, dyslipidaemia and the function of blood vessels. The new ....This Centre proposes to expand its highly successful Centre of Clinical Excellence funded by NHMRC from 1998-2001. The Centre provided the opportunity in Western Australia for the highest quality clinical research training in comprehensive spheres relevant to the pathogenesis, prevention and therapeutics of cardiovascular disease, with an emphasis on the role of nutrition and lifestyle in relation to high blood pressure, arteriosclerosis, dyslipidaemia and the function of blood vessels. The new Centre will broaden the scope of its research and training activities, through the inclusion of clinical projects related to heart failure, clinical and epidemiological research into cerebrovascular disease and stroke and research training opportunities with respect to clotting disorders and therapeutics for thrombosis.Read moreRead less
CCRE In Circulatory And Associated Conditions In Urban Indigenous Peoples
Funder
National Health and Medical Research Council
Funding Amount
$2,157,075.00
Summary
This Centre will focus on improving the prevention and management of circulatory and associated diseases in Aboriginal and Torres Strait Islander peoples living in urban areas. The Centre will conduct and promote high quality research that will lead to improved workforce development and training and service delivery to Urban Indigenous populations. The research program will be conducted jointly with the Queensland Aboriginal Islander Health Forum.
Metabolic disorders related to the modern lifestyle, including inactivity, obesity, the metabolic syndrome and type II diabetes, are responsible for a major proportion of the disease burden in Australia. Current treatment strategies are expensive and because they are directed at end-organ damage (heart failure, heart attacks etc), rather ineffective. This multispecialty, multidisciplinary group will undertake a series of unique studies aimed at understanding and preventing early cardiovascular c ....Metabolic disorders related to the modern lifestyle, including inactivity, obesity, the metabolic syndrome and type II diabetes, are responsible for a major proportion of the disease burden in Australia. Current treatment strategies are expensive and because they are directed at end-organ damage (heart failure, heart attacks etc), rather ineffective. This multispecialty, multidisciplinary group will undertake a series of unique studies aimed at understanding and preventing early cardiovascular complications of these metabolic conditions. Sensitive new cardiovascular imaging techniques will be used to detect preclinical abnormalities in the structure, function and metabolism of the heart and vasculature, facilitating the development of new strategies of exercise and lifestyle intervention to prevent these complications. While built on the successful current CCRE in Cardiovascular and Metabolic Disease, including multidisciplinary clinical research training, the new application involves major new directions in the interface between the liver and metabolic syndrome, and strategies for community-based prevention programs. The nursing intervention model, which will focus on workforce models of care, is especially important. The results of this study will provide information to address the need for different nursing models sought by the recent Productivity Commission Report.Read moreRead less
Centre Of Clinical Research Excellence In Renal Medicine
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
This Centre aims to answer important research questions such as: Does screening for early renal disease prevent kidney failure? Does renal disease in Aboriginal people begin in early childhood? What causes transplanted kidneys to fail? With the worldwide editorial base of the Cochrane Renal Group, the editorial base on the National Guidelines on Renal Disease and close links with the Master of Medicine (Clinical Epidemiology) program at the University of Sydney, this Centre will also provide pro ....This Centre aims to answer important research questions such as: Does screening for early renal disease prevent kidney failure? Does renal disease in Aboriginal people begin in early childhood? What causes transplanted kidneys to fail? With the worldwide editorial base of the Cochrane Renal Group, the editorial base on the National Guidelines on Renal Disease and close links with the Master of Medicine (Clinical Epidemiology) program at the University of Sydney, this Centre will also provide proven mechanisms for clinical research training and translation of research findings into clinical practice.Read moreRead less
Centre For Clinical Research Excellence In Respiratory And Sleep Medicine
Funder
National Health and Medical Research Council
Funding Amount
$2,200,000.00
Summary
The CCRE will enhance Australia's international research reputation in clinical respiratory and sleep medicine by enhancing links between hospital-based investigators. This will foster development of new clinical researchers in these fields. Major research projects will include reducing side effects of asthma therapy in the elderly, better and cheaper ways of diagnosing disorders such as sleep apnoea and blood clots in the lung, keeping patients with chronic lung diseases out of hospital and avo ....The CCRE will enhance Australia's international research reputation in clinical respiratory and sleep medicine by enhancing links between hospital-based investigators. This will foster development of new clinical researchers in these fields. Major research projects will include reducing side effects of asthma therapy in the elderly, better and cheaper ways of diagnosing disorders such as sleep apnoea and blood clots in the lung, keeping patients with chronic lung diseases out of hospital and avoiding accidents due to lack of sleep.Read moreRead less
Centre Of Clinical Research Excellence In Cardiovascular Disease And Metabolic Disorders
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
Cardiovascular complications are the main cause of morbidity in a number of metabolic diseases, including diabetes and renal failure. The Centre's objective is to bring together six successful clinical research groups in cardiovascular and metabolic disorders in collaboration with specialists in telemedicine, to address the interface between these diseases and to train a group of clinical researchers skilled in multi-disciplinary research. The planned research includes mechanistic studies as wel ....Cardiovascular complications are the main cause of morbidity in a number of metabolic diseases, including diabetes and renal failure. The Centre's objective is to bring together six successful clinical research groups in cardiovascular and metabolic disorders in collaboration with specialists in telemedicine, to address the interface between these diseases and to train a group of clinical researchers skilled in multi-disciplinary research. The planned research includes mechanistic studies as well as interventional studies that will be translated to clinical practice.Read moreRead less
The CCRE for Oral Health will focus on the prevention and treatment of oral diseases and disorders and their clinical consequences. Research will emphasise three areas of clinical care that are critical to the management of oral health, systemic health and general well-being: 1.Primary prevention to prevent disease onset 2. Diagnosis and risk prediction for oral conditions 3. Clinical intervention