Good nutrition is a vital element in a healthy start to life. Determining the correct foods to ensure that pregnant women meet both their needs as well as those of their new baby can be very confusing. Do I need to take iron supplements? How can I ensure I get enough iodine? This project will develop new methods for evaluating the effects of nutrients and to pass that information on to health practitioners so that Australian mothers will be in no doubt about the best diet for them and their chil ....Good nutrition is a vital element in a healthy start to life. Determining the correct foods to ensure that pregnant women meet both their needs as well as those of their new baby can be very confusing. Do I need to take iron supplements? How can I ensure I get enough iodine? This project will develop new methods for evaluating the effects of nutrients and to pass that information on to health practitioners so that Australian mothers will be in no doubt about the best diet for them and their children.Read moreRead less
Impact Of Parental Alcohol, Tobacco And Other Substance Use On Infant Development And Family Functioning
Funder
National Health and Medical Research Council
Funding Amount
$1,996,525.00
Summary
The current study will be the first large-scale Australian birth cohort study to comprehensively examine the effects of substance use in pregnant women and their partners during the prenatal period on infant developement and family functioning. Dramatically improved knowledge of these effects will provide evidence-based direction to the development of public health policy and community interventions that aim to improve the health and wellbeing of Australian children and families.
Centre Of Research Excellence (CRE) In Newborn Medicine
Funder
National Health and Medical Research Council
Funding Amount
$2,622,320.00
Summary
Problems around birth are common and can have long-term implications, including into adulthood. Our goal is to improve health outcomes for all newborn babies and their families by determining factors that enhance outcome and assessing the benefits and consequences of new treatments for mothers and babies. We are world leaders in this field and are dedicated to training the next generation of health professionals in the care of newborn babies, in Australia and the rest of the world.
Adolescent And Young Adult Parental Antecedent Of Health And Development In The First Year Of Life
Funder
National Health and Medical Research Council
Funding Amount
$566,331.00
Summary
In the past 50 years the gap between reproductive maturity at puberty and first childbirth has extended to around 2 decades. This coincides with a rise in mental disorders and substance use that has the potential to affect the health of babies and their mothers. This study will build on 20 years of work to test in a 1000 offspring the extent to which problems such as prematurity, post-natal depression and early mother-child relationships may be affected by earlier mental health and behaviour.
Retinal Photography To Assess Early Kidney Development In Indigenous Babies
Funder
National Health and Medical Research Council
Funding Amount
$888,098.00
Summary
The objective of this study is to identify infants who are at high risk off subsequent kidney failure . To achieve this objective, we plan to carry out comparison of kidney growth and function between Aboriginal and and non-Aboriginal infants from birth until they are 2 years old. We also hope to determine if changes in the blood vessels in these infants' eyes correspond to changes in the growing kidney- we are trying to determine if the eyes are the windows to the growing kidneys.
We are an international team committed to clinical trials to improve survival without disability in newborn babies. We plan a randomised trial to confirm if bovine lactoferrin, an inexpensive dairy protein, reduces death or major morbidity and increases total breast milk intake in 1,500 very low birthweight babies in neonatal intensive care units
A Randomised Trial Of An Early Parenting Intervention To Reduce Maternal Mood Disorder And Infant Behavior Disturbance
Funder
National Health and Medical Research Council
Funding Amount
$390,503.00
Summary
Over 242,000 women give birth annually in Australia and up to 20% experience significant psychological distress in the baby's first year. Severe fatigue, worrying and depression interfere with the development of maternal confidence. If a baby does not sleep well or feed easily or cries for prolonged periods, mothers can feel ineffective and helpless. Assistance early in the baby's life is important to avoid long-term emotional and behavioral problems for mother and child. Nationally, health and ....Over 242,000 women give birth annually in Australia and up to 20% experience significant psychological distress in the baby's first year. Severe fatigue, worrying and depression interfere with the development of maternal confidence. If a baby does not sleep well or feed easily or cries for prolonged periods, mothers can feel ineffective and helpless. Assistance early in the baby's life is important to avoid long-term emotional and behavioral problems for mother and child. Nationally, health and social policy focuses on assisting families including those with parental mental health and early parenting problems and children at risk of developmental difficulties. Australia's residential early parenting services are unique, offering brief treatment to mothers with difficulties and infants with unsettled behaviour. Parents are educated in infant care and provided with emotional support and assistance to adjust to the demands of parenting. In past studies by CIA and CIB women reported marked improvements in emotional distress, maternal confidence and infant manageability after completing this treatment and six months later. The education and emotional support were rated as acceptable and very effective. This project is a randomized controlled trial that will evaluate whether brief admission to a residential early parenting service has sustainable benefits for mild to moderate maternal mental health problems and for infant behaviour disturbance. Mothers with a diagnosable mental health condition and with four-month-old infants reported to have unsettled infant behaviour will be randomly assigned to a residential treatment program at an early parenting service or to routine care. Mothers and infants will be assessed with standardized psychological measures one month after treatment and when the baby is one year old. An effective and acceptable intervention will provide an important alternative to available treatments for postnatal psychological disturbance.Read moreRead less
Which Oxygen Saturation Level Should We Use For Very Premature Infants? A Randomised Controlled Trial.
Funder
National Health and Medical Research Council
Funding Amount
$2,215,600.00
Summary
Retinopathy of prematurity (ROP) is a serious complication of premature birth, and is a major cause of preventable blindness. Babies who are born before 28 weeks gestation are at greatest risk for developing severe ROP. Oxygen is one of the most common therapies used daily to care for premature babies, but high oxygen levels are one of multiple factors that can disrupt normal eye development and contribute to ROP. The current dilemma is that doctors and nurses do not know what level of oxygenati ....Retinopathy of prematurity (ROP) is a serious complication of premature birth, and is a major cause of preventable blindness. Babies who are born before 28 weeks gestation are at greatest risk for developing severe ROP. Oxygen is one of the most common therapies used daily to care for premature babies, but high oxygen levels are one of multiple factors that can disrupt normal eye development and contribute to ROP. The current dilemma is that doctors and nurses do not know what level of oxygenation is both safe and most effective for these babies. Whilst higher oxygen levels may increase ROP and other respiratory problems, it is possible that lower oxygen levels may affect other long-term outcomes. Because there is no definitive evidence regarding appropriate oxygenation, a wide spectrum of opinion and practice currently exist. Australia is conducting The Benefits of Oxygen Saturation Targeting Trial (BOOST II), a research study to solve this dilemma. BOOST II is a randomised, double blind, clinical trial, which will study the effects of using two ranges of oxygen saturation, 85-89% versus a higher range 91-95% for infants born before 28 weeks gestation. Both of these oxygen level ranges are currently used in normal practice. Patient safety will be monitored closely, and each infant will have their development, vision and health assessed by specialists at 18-24 months of age (plus the number of weeks premature), to see whether there is difference in survival free of major disability between the two groups. 1200 Australian infants will participate. This study will answer important questions about the benefits and risks of higher versus lower oxygen levels, and will improve the care of thousands of Australian children and millions more worldwide.Read moreRead less
A Randomised Controlled Trial Of Enhanced Parenting Capacity To Improve Developmental Outcomes In Preterm Infants
Funder
National Health and Medical Research Council
Funding Amount
$1,045,141.00
Summary
In Australia there are 2, 600 very preterm survivors each year. 50% will have education/behavioural difficulties and 10% major disability. We aim to optimise the development of infants born very preterm through a tailored Positive Parenting Program. We predict reductions in child behavioural and emotional problems at 2 years corrected age.