Centre Of Research Excellence (CRE) In Newborn Medicine
Funder
National Health and Medical Research Council
Funding Amount
$2,622,320.00
Summary
Problems around birth are common and can have long-term implications, including into adulthood. Our goal is to improve health outcomes for all newborn babies and their families by determining factors that enhance outcome and assessing the benefits and consequences of new treatments for mothers and babies. We are world leaders in this field and are dedicated to training the next generation of health professionals in the care of newborn babies, in Australia and the rest of the world.
Cash Transfers And Behaviour Change Communications To Reduce Child Undernutrition In Rural Bangladesh: A Cluster Randomized Controlled Trial To Determine The Most Effective Combination Of Interventions.
Funder
National Health and Medical Research Council
Funding Amount
$3,415,801.00
Summary
Under-nutrition of children remains a major global public health problem. Tackling this problem will require more evidence about what combination of nutrition-specific and nutrition sensitive interventions is most effective in reducing child undernutrition. We plan a large scale trial in rural Bangladesh to compare the effects of communications about nutrition with mobile phones and cash transfers in preventing child malnutrition.
Motor problems, ranging from clumsiness to cerebral palsy, are one of the most common adverse outcomes in children born early. This study will investigate the motor development of children born <30 weeks’ gestation compared with peers born at term from birth to 5 years. We will determine whether early clinical evaluations or neuroimaging in the newborn period can predict later motor impairment at 5 years to be able to identify those who will benefit most from early intervention.
Scalability Of The Transform-Us! Program To Promote Children's Physical Activity And Reduce Prolonged Sitting In Victorian Primary Schools
Funder
National Health and Medical Research Council
Funding Amount
$549,823.00
Summary
Transform-Us! is an innovative primary school program that has been found to substantially increase children’s physical activity levels, reduce sitting time and benefit health. With simple changes to the school and classroom environments and teaching practices (eg, standing lessons) we will work with partners in the education and health systems to translate this program across Victorian primary schools to determine the real-world implementation and impact of this program over 5 years.
Examining The Metabolic And Cognitive Deficits Caused By Insulin Resistance In The Ventral Striatum
Funder
National Health and Medical Research Council
Funding Amount
$400,372.00
Summary
Brain insulin resistance is thought to cause metabolic and cognitive deficits, but the underlying neural mechanisms remain elusive. This project addresses this gap in our knowledge by examining how brain insulin resistance disrupts the metabolic regulation of food intake and the cognitive control of actions. The outcomes will provide new insights in disorders characterised by brain insulin resistance such as obesity and dementia.
1+1- A Healthy Start To Life:Targeting The Year Before And The Year After Birth In Aboriginal Children In Remote Areas
Funder
National Health and Medical Research Council
Funding Amount
$587,272.00
Summary
Indigenous Australians in remote communities are less healthy and more socially disadvantaged than other Australians. This influences the quality of the intrauterine environment. Babies often suffer malnutrition and recurring infections during infancy which are exacerbated by their less than optimal birth status and contribute to chronic conditions (diabetes, cardiovascular disease, renal failure) in adulthood. Existing health services are costly to Government and do not achieve their potential ....Indigenous Australians in remote communities are less healthy and more socially disadvantaged than other Australians. This influences the quality of the intrauterine environment. Babies often suffer malnutrition and recurring infections during infancy which are exacerbated by their less than optimal birth status and contribute to chronic conditions (diabetes, cardiovascular disease, renal failure) in adulthood. Existing health services are costly to Government and do not achieve their potential for promoting health and providing quality care. Evidence suggests redesigned models based on continuity of care, focused, proactive family support and workload reform will improve maternal and infant outcomes. New models need to be developed, costed, implemented and evaluated providing governments with the evidence base to initiate service improvement. Such models will have applicability elsewhere in Australia. Professor Lesley Barclay and her team of researchers from Charles Darwin University will conduct research into developing such a model. The project aims to improve the quality of care for remote dwelling Aboriginal women and infants in the year before, during and the year after birth by providing evidence for, and facilitating changes to, service delivery. This will enhance the potential for the development of resilience and well-being of their children. It will also test if service improvements can improve the health of women and reduce childhood disease and therefore reduce the impact of health conditions occurring in adulthood which have their origins in the early stages of life.Read moreRead less
(When) should organisations employ over/underqualified individuals? The aim of the project is to better understand how employee qualifications (ie the extent to which an employee is qualified for the job they hold) influences their voluntary turnover decisions and job performance. Demand and supply in the labour market are frequently out of sync; around half of Australian employees have a level of qualification that does not match the position in which they are currently working. The project aim ....(When) should organisations employ over/underqualified individuals? The aim of the project is to better understand how employee qualifications (ie the extent to which an employee is qualified for the job they hold) influences their voluntary turnover decisions and job performance. Demand and supply in the labour market are frequently out of sync; around half of Australian employees have a level of qualification that does not match the position in which they are currently working. The project aims to establish under what conditions organisations and employees can get the performance benefits from employee qualifications while avoiding fast rates of voluntary turnover. The goal of the project is to develop insights about how to make full use of the benefits of qualifications while avoiding the pitfalls. Insights from this research may be of potential benefit to both workers and to employing organisations.Read moreRead less
Does Caffeine Affect The Development Of The Very Immature Brain: Dose Response Relationship?
Funder
National Health and Medical Research Council
Funding Amount
$668,386.00
Summary
Premature birth is a major health problem worldwide. Preterm babies often develop apnoea of prematurity (AOP), which is commonly treated with caffeine. Trials indicate that preterm babies treated with low dose caffeine have less neurodevelopmental disabilities at 18 months. Higher doses of caffeine are often needed to reduce AOP but the risk of this is unknown. We will study the short and long-term effects of increasing doses of caffeine on the developing brain in a long-gestation species.
Flexible methods for latent variable models applied to Health Economics. This project aims to develop flexible and powerful methods for estimating models containing variables that are unobserved, that is, latent. Such models are often used to capture individual heterogeneity and time dependence in data collected on individuals, with each individual observed for several time periods. Latent variables can also infer group membership, where such membership is unavailable from the data. The intended ....Flexible methods for latent variable models applied to Health Economics. This project aims to develop flexible and powerful methods for estimating models containing variables that are unobserved, that is, latent. Such models are often used to capture individual heterogeneity and time dependence in data collected on individuals, with each individual observed for several time periods. Latent variables can also infer group membership, where such membership is unavailable from the data. The intended methodology is Bayesian and based on new particle methods that allow users to select between models and predict future observations even in complex situations. The research aims to inform decision making through improved use of data in health economics and related fields.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100887
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Economic analysis of time constraints on decision-making in health. This project aims to determine whether and how time constraints affect decision-making. Time constraints can impair the quality of decisions in health, resulting in serious medical and financial consequences. This project will employ experimental economic methods to examine how misaligned preferences and incentives influence decision-making under time constraints. The project will offer scientific evidence and accurate measureme ....Economic analysis of time constraints on decision-making in health. This project aims to determine whether and how time constraints affect decision-making. Time constraints can impair the quality of decisions in health, resulting in serious medical and financial consequences. This project will employ experimental economic methods to examine how misaligned preferences and incentives influence decision-making under time constraints. The project will offer scientific evidence and accurate measurements, provide insights into interventions to align the preferences of doctors and patients, and to lower the overtreatment of patients in the health-care market. The project expects to benefit society and contribute to a more efficient healthcare system.Read moreRead less