An Integrated Biotechnological Process for Production of Lactic Acid from Carbohydrate-Waste Streams by Rhizopus sp. Lactic acid is the most widely occurring multifunctional organic acid. It has enormous applications in food and food-related industries, and great potential use for production of biodegradable and biocompatible polylactate polymers. The aim of this research is to develop an innovative biotechnological process, incorporating simultaneous saccharification and fermentation, which int ....An Integrated Biotechnological Process for Production of Lactic Acid from Carbohydrate-Waste Streams by Rhizopus sp. Lactic acid is the most widely occurring multifunctional organic acid. It has enormous applications in food and food-related industries, and great potential use for production of biodegradable and biocompatible polylactate polymers. The aim of this research is to develop an innovative biotechnological process, incorporating simultaneous saccharification and fermentation, which integrates the production of lactic acid with the treatment of high strength food industry ?effluent? streams - carbohydrate waste streams. The proposed SSF process will cultivate an identified fungal Rhizopus sp strain on the waste streams, as production substrates, leading to an environmentally friendly and economically sustainable new technology for the food industry.Read moreRead less
Miniaturised biosensors with high selectivity . This project aims to develop a technological platform for the fabrication of miniaturised and flexible sensors that enable the quantitative detection of important bioactive compounds such as fatty acids and biogenic amines. By utilising multi-enzymatic reactions in solid phase and engineering task-specific inks, chemiresistive sensors will be printed seamlessly as a whole. The sensors will respond to complex target biomolecules via a series of enzy ....Miniaturised biosensors with high selectivity . This project aims to develop a technological platform for the fabrication of miniaturised and flexible sensors that enable the quantitative detection of important bioactive compounds such as fatty acids and biogenic amines. By utilising multi-enzymatic reactions in solid phase and engineering task-specific inks, chemiresistive sensors will be printed seamlessly as a whole. The sensors will respond to complex target biomolecules via a series of enzymatic reactions through which the analyte will convert to much simpler, reactive and hence measurable molecules. This project will enable to design miniaturised sensors for point-of-care detection of biomolecules that cannot be yet evaluated by the end users.Read moreRead less
Development of a Novel Process for the Formation of Polymer Vesicles. The project would provide an increased understanding of polymer structures, polymer-drug interactions and dense gas processing of polymers. The novel process developed would be beneficial on a manufacturing level since it dramatically reduces processing time and minimises energy requirements. The research to be conducted is leading-edge technology that will attract business from international polymer, drug and biotechnology co ....Development of a Novel Process for the Formation of Polymer Vesicles. The project would provide an increased understanding of polymer structures, polymer-drug interactions and dense gas processing of polymers. The novel process developed would be beneficial on a manufacturing level since it dramatically reduces processing time and minimises energy requirements. The research to be conducted is leading-edge technology that will attract business from international polymer, drug and biotechnology companies. The development of world-class research provides Australia with recognition as a world leader in the field and strengthens and broadens the knowledge base of Australian scientists and engineers.Read moreRead less
Guided droplet deposition: Microfabrication of advanced materials. The progress of micro and nanofabrication is opening an array of new opportunities with a new degree of freedom for manufacturing. This process will complement the existing micromanufacturing facilities in Melbourne. While metal printing and deposition of polymers is presently available, the guided droplet deposition will extend current capabilities to include ceramics and high melting temperature metals. Direct application to me ....Guided droplet deposition: Microfabrication of advanced materials. The progress of micro and nanofabrication is opening an array of new opportunities with a new degree of freedom for manufacturing. This process will complement the existing micromanufacturing facilities in Melbourne. While metal printing and deposition of polymers is presently available, the guided droplet deposition will extend current capabilities to include ceramics and high melting temperature metals. Direct application to medical devices will provide a more effective surface for improved performance and allow the incorporation of smart and sensor materials for multifunctional devices. Read moreRead less
Clean technologies for the synthesis and purification of a biohybrid and biodegradable polymer. The project aims to transform an Australian industry in the forefront of the global market for manufacturing biodegradable polymers and boost export earnings derived from CO2 based biohybrid polymers. The project will develop cost-effective and clean methods for processing CO2 based polymers and demonstrate its potential for packaging and biomedical applications.
Failure of Complex Biomechanical Structures. Layer structures are replete in biological systems, both natural and artificial. Issues concerning the lifetime of such systems are paramount to the quality of life and economic well being of our aging society. Our project will analyse damage in brittle layer systems that simulate dental crown structures. We are now at a critical point in the understanding of how these structures fail, and are beginning to make substantive predictions to improve des ....Failure of Complex Biomechanical Structures. Layer structures are replete in biological systems, both natural and artificial. Issues concerning the lifetime of such systems are paramount to the quality of life and economic well being of our aging society. Our project will analyse damage in brittle layer systems that simulate dental crown structures. We are now at a critical point in the understanding of how these structures fail, and are beginning to make substantive predictions to improve designs for prolonged life. The project is connected to the dental community and international crown material manufacturers through a broader NIH project in the USA. The improved materials and crown designs resulting from this project will have impact worldwide, including Australia.Read moreRead less
Failure of Worn Tooth Structures. Layer structures are replete in biological systems, both natural and artificial. Issues concerning the lifetime of such systems are paramount to the quality of life and economic well being of our aging society. Our project will analyse damage in brittle layer systems that simulate natural teeth and dental crown structures that have been subject to wear. The project is connected to the dental community and international crown material manufacturers through a bro ....Failure of Worn Tooth Structures. Layer structures are replete in biological systems, both natural and artificial. Issues concerning the lifetime of such systems are paramount to the quality of life and economic well being of our aging society. Our project will analyse damage in brittle layer systems that simulate natural teeth and dental crown structures that have been subject to wear. The project is connected to the dental community and international crown material manufacturers through a broader National Institutes of Health project in the USA. The improved understanding of damage mechanisms in natural teeth and crown designs resulting from this project will have impact worldwide, including Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883056
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Vacuum Ultraviolet Spectrophotometer and Rapid Photoluminescence Mapping System for Development of Advanced Materials and Biosystems. Australia's energy and renewable energy, defence, biosystem and pharmaceutical industries are spearheading the advancement of technologies in the global competitive market. They are the engines of Australian economy's strength. Future progress of these industries is expected to be largely driven by advances in materials and biosystems. The installation of the p ....Vacuum Ultraviolet Spectrophotometer and Rapid Photoluminescence Mapping System for Development of Advanced Materials and Biosystems. Australia's energy and renewable energy, defence, biosystem and pharmaceutical industries are spearheading the advancement of technologies in the global competitive market. They are the engines of Australian economy's strength. Future progress of these industries is expected to be largely driven by advances in materials and biosystems. The installation of the proposed facilities will add a new dimension to high-level research performance and significantly enhance the capability for characterization of various forms of materials and biosystems in Australia. The continual development of advanced material and biosystem technology will potentially provide a sustainable means for meeting the increasing global challenge for the industries.Read moreRead less
Cellular control mechanisms of matrix mineralization in the teeth of marine molluscs. These studies are significant as a foundation for the country's current focus on advanced materials and nanotechnology. The production of new materials is critically dependant upon understanding the crystallochemical control organisms, such as chitons and limpets, have over the precipitation of simple compounds, such as the calcium and iron oxides, phosphates and silica, often formed as nanoscale deposits. This ....Cellular control mechanisms of matrix mineralization in the teeth of marine molluscs. These studies are significant as a foundation for the country's current focus on advanced materials and nanotechnology. The production of new materials is critically dependant upon understanding the crystallochemical control organisms, such as chitons and limpets, have over the precipitation of simple compounds, such as the calcium and iron oxides, phosphates and silica, often formed as nanoscale deposits. This study constitutes a systematic in situ exploration of the biomineralization processes that form these composite microstructures and as such will provide a new source of inspiration to the production of new biomaterials.Read moreRead less
Nanostructured Degradable Polymer for Drug Delivery. The success of synthesising nanostructured degradable polymers will position Australia at the world forefront in the field of nanotechnology, bioengineering and healthcare sectors in both fundamental and applied research. This multi-disciplinary research has the potential to generate patentable technologies with economic benefits to Australia. The project also involves fundamental research into surface chemistry, nanostructure, polymer science ....Nanostructured Degradable Polymer for Drug Delivery. The success of synthesising nanostructured degradable polymers will position Australia at the world forefront in the field of nanotechnology, bioengineering and healthcare sectors in both fundamental and applied research. This multi-disciplinary research has the potential to generate patentable technologies with economic benefits to Australia. The project also involves fundamental research into surface chemistry, nanostructure, polymer sciences and will be a meaningful contribution to the advancement of scientific knowledge in Australia. All these will enhance the international competitive profile of Australia in the field of nanotechnology for drug delivery.Read moreRead less