Special Research Initiatives - Grant ID: SR0354787
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 biorem ....Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 bioremediation and algal/bacterial systems for the bioremediation of contaminated soils. This will be achieved by applying research on photosynthetic light utilisation efficiency and carbon fixation, chlorophyll fluorescence, biochemistry of secondary metabolites, molecular biology and photobioreactor design and engineering, informed by an understanding of the ecology of these algae.Read moreRead less
Multipurpose separation platforms for protein purification. Over the next decades, many new therapies and products will be needed to enhance the quality of human life. Biopharmaceuticals and other protein-based products will thus be increasingly in demand. This will require significant improvements in biotechnological procedures, particularly sophisticated purification technologies. Through the development of a novel technology, this project is anticipated to significantly contribute to these so ....Multipurpose separation platforms for protein purification. Over the next decades, many new therapies and products will be needed to enhance the quality of human life. Biopharmaceuticals and other protein-based products will thus be increasingly in demand. This will require significant improvements in biotechnological procedures, particularly sophisticated purification technologies. Through the development of a novel technology, this project is anticipated to significantly contribute to these societal needs and provide a new way to purify these important molecules. National and community benefits will accrue from this scientific innovation and from its application, which is expected to provide more efficient manufacturing opportunities for key biotechnology industries.Read moreRead less
Novel Technologies for the Purification of Recombinant Proteins. Availability of enabling technologies for the large-scale purification of recombinant proteins is an essential requirement of the biotechnology industry. This project aims to integrate two concepts in molecular biorecognition. New modalities of immobilised metal ion affinity chromatography will be linked with the selection of new types of peptide affinity handles that can be inserted by genetic engineering methods into proteins pro ....Novel Technologies for the Purification of Recombinant Proteins. Availability of enabling technologies for the large-scale purification of recombinant proteins is an essential requirement of the biotechnology industry. This project aims to integrate two concepts in molecular biorecognition. New modalities of immobilised metal ion affinity chromatography will be linked with the selection of new types of peptide affinity handles that can be inserted by genetic engineering methods into proteins produced by biotechnological procedures. The approach followed then allows these handles to be removed following isolation of the target protein. This project could thus lead to a considerable advance in the manufacture of recombinant proteins intended for human therapy.Read moreRead less
Biological Leaching of Low Grade Nickel Laterite Ores. Harnessing the capability of fungi to dissolve large quantities of nickel and cobalt from laterite ores will create a step change in the technology for processing nickel laterites and other oxide minerals. Using microorganisms and their metabolic products promises to be effective, energy saving, easily controlled and environmentally safe. The mechanistic investigation proposed in this study will generate fundamental innovations and technolo ....Biological Leaching of Low Grade Nickel Laterite Ores. Harnessing the capability of fungi to dissolve large quantities of nickel and cobalt from laterite ores will create a step change in the technology for processing nickel laterites and other oxide minerals. Using microorganisms and their metabolic products promises to be effective, energy saving, easily controlled and environmentally safe. The mechanistic investigation proposed in this study will generate fundamental innovations and technological advancement in bio-leaching of laterite ores. Such technologies can secure the sustainability of nickel production and provide unique ecological reform to the mineral extraction industry.Read moreRead less
Life Extension of Equipment Suffering Environmentally-Assisted Cracking: An Innovative Approach to Mitigation by Engineering of Materials in Service. Environmentally-assisted cracking (EAC) represents a serious threat to infrastructure exposed to caustic and chloride environments in process, marine, energy and chemical industries in Australia. Despite extensive research, there is no consensus mechanism for EAC. This project will investigate a fresh approach to life extension of in-service equipm ....Life Extension of Equipment Suffering Environmentally-Assisted Cracking: An Innovative Approach to Mitigation by Engineering of Materials in Service. Environmentally-assisted cracking (EAC) represents a serious threat to infrastructure exposed to caustic and chloride environments in process, marine, energy and chemical industries in Australia. Despite extensive research, there is no consensus mechanism for EAC. This project will investigate a fresh approach to life extension of in-service equipment suffering EAC, by developing and testing a mitigation measure reasonably independent of the EAC mechanisms. The task includes development of a consolidated strategy based on: accurate determination of the fundamental parameters for crack propagation, and in-situ thermomechnical treatment for local manipulation of material at and ahead of crack-tip, in order to retard/stop crack propagation.Read moreRead less
Single walled carbon nanotubes of one stereochemistry - material for the oncoming carbon age. Carbon nanotubes are finding application in nanotechnology. However currently they are prepared as a mixture of zig-zag, chiral and armchair isomers. Their properties could be improved if they could be prepared with one stereochemistry. The approach here is to use a nanocrystallisation and thermal maturation process involving stereo controlling additives. The new carbons are expected to have outstandin ....Single walled carbon nanotubes of one stereochemistry - material for the oncoming carbon age. Carbon nanotubes are finding application in nanotechnology. However currently they are prepared as a mixture of zig-zag, chiral and armchair isomers. Their properties could be improved if they could be prepared with one stereochemistry. The approach here is to use a nanocrystallisation and thermal maturation process involving stereo controlling additives. The new carbons are expected to have outstanding flexibility and strength and novel thermal and electrical properties. The new products could give Australia a lead in new battery, hydrogen storage, flat screen technology and nanoelectronics.Read moreRead less
Nanostructured Degradable Polymer for Drug Delivery. The success of synthesising nanostructured degradable polymers will position Australia at the world forefront in the field of nanotechnology, bioengineering and healthcare sectors in both fundamental and applied research. This multi-disciplinary research has the potential to generate patentable technologies with economic benefits to Australia. The project also involves fundamental research into surface chemistry, nanostructure, polymer science ....Nanostructured Degradable Polymer for Drug Delivery. The success of synthesising nanostructured degradable polymers will position Australia at the world forefront in the field of nanotechnology, bioengineering and healthcare sectors in both fundamental and applied research. This multi-disciplinary research has the potential to generate patentable technologies with economic benefits to Australia. The project also involves fundamental research into surface chemistry, nanostructure, polymer sciences and will be a meaningful contribution to the advancement of scientific knowledge in Australia. All these will enhance the international competitive profile of Australia in the field of nanotechnology for drug delivery.Read moreRead less
Engineering models for inland atmospheric corrosion of steel infrastructure considering microbiological and environmental influences. Some 2-3% of Gross Domestic Product is estimated to be lost every year to corrosion and by measures to counteract it. Of this a significant proportion relates to steel infrastructure, which includes buildings, bridges, transmission towers, ships, offshore and coastal structures, tanks and pipelines. Better understanding and modelling of corrosion will improve our ....Engineering models for inland atmospheric corrosion of steel infrastructure considering microbiological and environmental influences. Some 2-3% of Gross Domestic Product is estimated to be lost every year to corrosion and by measures to counteract it. Of this a significant proportion relates to steel infrastructure, which includes buildings, bridges, transmission towers, ships, offshore and coastal structures, tanks and pipelines. Better understanding and modelling of corrosion will improve our capability for assessing the long-term safety and serviceability of infrastructure. It may also be useful in improving the composition of steel to resist rusting and in the formulation of protective coatings. This project will contribute to better understanding of the likely involvement of bacteria in the longer-term corrosion of steel exposed to various inland environments.Read moreRead less
Mathematical and mechanical modeling of nano particulate flow. Nano particulates are the basis for many new technologies, including coatings in the electronics industry, composite materials and medical and pharmaceutical applications. Worldwide industrial competition is increasingly determined by our capacity to handle such highly cohesive materials, and to exploit their novel physical, chemical and mechanical characteristics. Devising handling mechanisms and understanding nano particulate flows ....Mathematical and mechanical modeling of nano particulate flow. Nano particulates are the basis for many new technologies, including coatings in the electronics industry, composite materials and medical and pharmaceutical applications. Worldwide industrial competition is increasingly determined by our capacity to handle such highly cohesive materials, and to exploit their novel physical, chemical and mechanical characteristics. Devising handling mechanisms and understanding nano particulate flows depends on formulating accurate mathematical models which reflect the correct underlying physics. This APF proposal will utilise advanced continuum mechanics to develop the correct underlying conceptual ideas to resolve fundamental nanomechanical particulate flows, which will lead to the next generation of engineering tools.
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Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas.
X-ray and neutron scattering techniques, de ....Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas.
X-ray and neutron scattering techniques, developed by us, allow the interfacial structure of the surfactant to be found and the intellectual "loop" closed in the design process. Preliminary screening will be done using the surface balance and bulk emulsion synthesis.Read moreRead less