Probing microbial emulsions to break barriers to green oil production. This project aims to understand ultrasonic processing of concentrated slurries of oil-bearing yeast and algae. Humans must reduce their dependency on petroleum. While microorganisms can produce oils as replacement fuels and base chemicals, the processes for extracting these oils are inefficient. Ultrasound could improve oil recovery by replacing toxic solvents. Understanding the effects of ultrasound on microbial emulsions is ....Probing microbial emulsions to break barriers to green oil production. This project aims to understand ultrasonic processing of concentrated slurries of oil-bearing yeast and algae. Humans must reduce their dependency on petroleum. While microorganisms can produce oils as replacement fuels and base chemicals, the processes for extracting these oils are inefficient. Ultrasound could improve oil recovery by replacing toxic solvents. Understanding the effects of ultrasound on microbial emulsions is expected to develop solvent-free oil recovery processes that improve the economic and environmental benefits of microbial oil production. Such processes would greatly increase the efficiency and reduce the cost of producing microbial oils that can be used as green alternatives to petroleum fuels and chemicals.Read moreRead less
Contribution of Comammox Process to Sustainable Wastewater Treatment. This project aims to understand the versatility, activity and physiological features of comammox bacteria, the newly-discovered complete nitrifiers, in Australian wastewater treatment systems, and to model and evaluate their contributions to biological nitrogen removal process. Nitrogen transformations are crucial microbial processes in the wastewater treatment ecosystems, with nitrification largely responsible for ammonium ox ....Contribution of Comammox Process to Sustainable Wastewater Treatment. This project aims to understand the versatility, activity and physiological features of comammox bacteria, the newly-discovered complete nitrifiers, in Australian wastewater treatment systems, and to model and evaluate their contributions to biological nitrogen removal process. Nitrogen transformations are crucial microbial processes in the wastewater treatment ecosystems, with nitrification largely responsible for ammonium oxidation but comammox previously overlooked. The expected outcomes will develop new knowledge on the comammox process and provide novel insight and technological solution to refine strategies to manipulate nitrification processes for achieving improved biological nitrogen removal and sustainable wastewater management.Read moreRead less
Ultrasound-assisted fabrication of biofunctional materials. The project aims to develop a fundamental understanding of the mechanism involved in the synthetic process in order to control the physical and functional properties of core-shell biomaterials. Biofunctional core-shell materials are of scientific interest due to their potential use in a variety of applications including food manufacturing. Among existing methodologies for the synthesis of core-shell biomaterials, ultrasonic technology o ....Ultrasound-assisted fabrication of biofunctional materials. The project aims to develop a fundamental understanding of the mechanism involved in the synthetic process in order to control the physical and functional properties of core-shell biomaterials. Biofunctional core-shell materials are of scientific interest due to their potential use in a variety of applications including food manufacturing. Among existing methodologies for the synthesis of core-shell biomaterials, ultrasonic technology offers versatility and a wider choice of core and shell materials possessing specific biofunctionality. The outcomes of this project may include the establishment of a versatile technology for the fabrication of tailor-made biofunctional materials suitable for specific applications.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100667
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Removing a Key Barrier for Autotrophic Nitrogen Removal from Wastewater. This project aims to develop new technology to enable stable autotrophic nitrogen removal from domestic wastewater. The technology selectively suppresses the growth of nitrite-oxidising bacteria using a by-product of wastewater treatment – free nitrous acid. Maximising energy recovery from wastewater and providing greenhouse gas neutral water services have been the targets of water utilities in Australia and worldwide. The ....Removing a Key Barrier for Autotrophic Nitrogen Removal from Wastewater. This project aims to develop new technology to enable stable autotrophic nitrogen removal from domestic wastewater. The technology selectively suppresses the growth of nitrite-oxidising bacteria using a by-product of wastewater treatment – free nitrous acid. Maximising energy recovery from wastewater and providing greenhouse gas neutral water services have been the targets of water utilities in Australia and worldwide. The project will potentially change wastewater management and bring economic, environmental and social benefits to water utilities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100043
Funder
Australian Research Council
Funding Amount
$435,279.00
Summary
High-throughput portable and wearable device fabrication facility. This project aims to establish a fabrication and characterisation facility for high-throughput production of portable, wearable and stretchable biomedical devices to accelerate the design–fabrication–evaluation process and save ‘trial-and-error’ costs during optimisation turnaround. It will apply computer-aided design for the programmable synthesis of hybrid materials for high-throughput screening of disease biomarkers, and super ....High-throughput portable and wearable device fabrication facility. This project aims to establish a fabrication and characterisation facility for high-throughput production of portable, wearable and stretchable biomedical devices to accelerate the design–fabrication–evaluation process and save ‘trial-and-error’ costs during optimisation turnaround. It will apply computer-aided design for the programmable synthesis of hybrid materials for high-throughput screening of disease biomarkers, and super-solution imaging of single molecules in live cells. This facility will provide capability for researchers pursuing industry transformation and other initiatives in the development of advanced materials, biomolecular sciences, nanotechnology, photonics and device engineering.Read moreRead less
Bacterial detection and infection control using tethered membranes. This project will develop a rapid diagnostic tool to detect live bacteria, which will subsequently reduce risk of infection, increase efficiencies in patient care and hospital management, and produce savings in health care budgets. It also has the potential to save lives through addressing the serious and growing problem of antibiotic resistance.
In situ bioremediation solutions for Australia's organochlorine contaminated aquifers. This project will develop biological technologies to accelerate chlorinated solvent degradation in contaminated groundwater. Bacterial cultures developed in Australia will be injected into groundwater to enhance solvent degradation resulting in environmentally friendly and cost effective environmental restoration.
Surveillance of the mechanisms controlling proteome foldedness. This project aims to measure how cells keep the proteome folded. Cells have extensive quality control networks to govern synthesis, folding and transport of every protein but the buffering capacity of this system is not definable. This capacity is needed to understand how problems arise in managing proteome foldedness, a central feature of human diseases and biotechnology and synthetic biology applications that need cell-based produ ....Surveillance of the mechanisms controlling proteome foldedness. This project aims to measure how cells keep the proteome folded. Cells have extensive quality control networks to govern synthesis, folding and transport of every protein but the buffering capacity of this system is not definable. This capacity is needed to understand how problems arise in managing proteome foldedness, a central feature of human diseases and biotechnology and synthetic biology applications that need cell-based production of engineered proteins such as hormones and antibodies. The outcomes are expected to provide basic knowledge of this fundamental process and provide biosensors and screening methods for use in health and biotechnology industries.Read moreRead less
Development of class-leading bioluminescence resonance energy transfer technologies for real-time monitoring of molecular interactions. The purpose of this project is to develop improved technologies for identifying and developing pharmaceuticals with fewer side effects. The expected outcome is the development of technologies that provide a level of sensitivity and data quality that enables adoption by the biotechnology and pharmaceutical industries.
Discovery Early Career Researcher Award - Grant ID: DE220100311
Funder
Australian Research Council
Funding Amount
$383,982.00
Summary
Shining nanoparticles for single microRNA detection in microfluidics. This project aims to extensively study the interface between nanoparticles and nucleic acids. It sets out to produce a novel ultrasensitive high-performance biosensing platform that will combine luminescent nanoparticles with microfluidics in a digital assay. This portable platform will detect biological fingerprints, or microRNAs, at a single-molecule level, delivering unprecedented levels of sensitivity and specificity. The ....Shining nanoparticles for single microRNA detection in microfluidics. This project aims to extensively study the interface between nanoparticles and nucleic acids. It sets out to produce a novel ultrasensitive high-performance biosensing platform that will combine luminescent nanoparticles with microfluidics in a digital assay. This portable platform will detect biological fingerprints, or microRNAs, at a single-molecule level, delivering unprecedented levels of sensitivity and specificity. The multiplexed platform has the potential to benefit the biomedical research of microRNAs and opens up a genuine commercialisation potential for portable biosensing of nucleic acids.Read moreRead less