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Long-term memory systems and the human brain. Impairment of memory is a ubiquitous feature of human brain disease. A better understanding of memory processing in the brain is key to the development of better tests for the detection and monitoring of disease progression as well as the application of improved methods of rehabilitation for patients with acquired brain injury. This project will provide the catalyst for the development of a National Memory Disorders Research Centre that would be the ....Long-term memory systems and the human brain. Impairment of memory is a ubiquitous feature of human brain disease. A better understanding of memory processing in the brain is key to the development of better tests for the detection and monitoring of disease progression as well as the application of improved methods of rehabilitation for patients with acquired brain injury. This project will provide the catalyst for the development of a National Memory Disorders Research Centre that would be the focus for multidisciplinary cognitive neuroscience research. The ultimate aim would be the translation of basic neuroscience into effective tools that will impact the health outcome of the ageing population.Read moreRead less
Human long-term memory and social cognition: an integrated cognitive neuroscience approach. Impairment of memory is a ubiquitous feature of the dementias and a better understanding of memory processing in the brain is key to the development of better tests for the early detection and monitoring of disease progression. The study of social cognition is relevant to a range of developmental, psychiatric and neurological disorders. This project will provide the catalyst for the development of a Natio ....Human long-term memory and social cognition: an integrated cognitive neuroscience approach. Impairment of memory is a ubiquitous feature of the dementias and a better understanding of memory processing in the brain is key to the development of better tests for the early detection and monitoring of disease progression. The study of social cognition is relevant to a range of developmental, psychiatric and neurological disorders. This project will provide the catalyst for the development of a National Memory and Cognitive Disorders Centre that would be the focus for multidisciplinary cognitive neuroscience research. The ultimate aim would be the translation of basic neuroscience into effective tools that will impact the health outcomes of the ageing population.Read moreRead less
From Nanostructured Functional Materials to Sustainable Processes. Nano-structured functional materials in the areas of catalysis and reversible hydrogen storage will be developed with the view to arrive at (a) sustainable processes and (b) the adoption of hydrogen as an energy carrier. These aims are driven by a global need to change the industrial paradigm due to environmental pressures and limited resources, particularly in terms of energy. Expected outcomes are new avenues to process intens ....From Nanostructured Functional Materials to Sustainable Processes. Nano-structured functional materials in the areas of catalysis and reversible hydrogen storage will be developed with the view to arrive at (a) sustainable processes and (b) the adoption of hydrogen as an energy carrier. These aims are driven by a global need to change the industrial paradigm due to environmental pressures and limited resources, particularly in terms of energy. Expected outcomes are new avenues to process intensification, leading to novel commercial routes, and a hydrogen storage technology which has the potential to play a strong part in the global economy.Read moreRead less
Band-Gap Engineered Visible Light Photocatalysts: Enabling Technologies for Sustainable Energy and the Environment. This program will contribute significantly to knowledge advancement in colloid chemistry, nanomaterials and electrochemistry, and is firmly embedded in the National Research Priorities of Frontier Science and an Environmentally Sustainable Australia. In particular, it addresses the goals of water and low emission energy supply. The outcomes of this research will advance a new class ....Band-Gap Engineered Visible Light Photocatalysts: Enabling Technologies for Sustainable Energy and the Environment. This program will contribute significantly to knowledge advancement in colloid chemistry, nanomaterials and electrochemistry, and is firmly embedded in the National Research Priorities of Frontier Science and an Environmentally Sustainable Australia. In particular, it addresses the goals of water and low emission energy supply. The outcomes of this research will advance a new class of visible-light active photocatalysts that underpin the development of hydrogen generation, low cost solar cells and water purification using sunlight. Such technologies will transform the Australian energy and environmental industries and speed up the transition from a fossil fuel economy to a renewable energy economy.Read moreRead less
Engineered optical fibre device structures for next generation telecommunication systems. The next generation of optical telecommunication networks requires novel photonic compnents that are superior to current devices, and cannot be obtained by incremental improvement. This project will identify novel device architectures and implement these in practical devices. This will ensure that Australia remains at the cutting edge of photonics research, one of the most dynamic and exciting ereas in sc ....Engineered optical fibre device structures for next generation telecommunication systems. The next generation of optical telecommunication networks requires novel photonic compnents that are superior to current devices, and cannot be obtained by incremental improvement. This project will identify novel device architectures and implement these in practical devices. This will ensure that Australia remains at the cutting edge of photonics research, one of the most dynamic and exciting ereas in science and engineering and at the basis of a multibillion dollar industry.Read moreRead less
Language, belief formation and visual cognition: cognitive and neuropsychological investigations. I will direct a programme of research and research training in cognitive science and cognitive neuropsychology at macquarie universtiy, with international collaborative links to the USA, Canada, France, Italy, Spain, Germany & New Zealand. This programme of research and research training will initially focus on
a)how people understand and produce language, and how these capabilities can break down ....Language, belief formation and visual cognition: cognitive and neuropsychological investigations. I will direct a programme of research and research training in cognitive science and cognitive neuropsychology at macquarie universtiy, with international collaborative links to the USA, Canada, France, Italy, Spain, Germany & New Zealand. This programme of research and research training will initially focus on
a)how people understand and produce language, and how these capabilities can break down after brain damage;
b)The relationship between visual memory and reading; and
c)The nature of the delusions seen in schizophrenia and other disorders, and what causes these delusions.Read moreRead less
Creation of novel photonic and nanostructured materials by ablation of solids with ultra-fast lasers. This project will study of the production of technologically important thin film materials and nanostructured materials using our patented ultra-fast pulsed laser deposition process. Thin film materials required for future applications in photonics will be a priority. In addition ultra-fast pulsed laser deposition can be used to create nanopartilces and mechanisms affecting the growth of these ....Creation of novel photonic and nanostructured materials by ablation of solids with ultra-fast lasers. This project will study of the production of technologically important thin film materials and nanostructured materials using our patented ultra-fast pulsed laser deposition process. Thin film materials required for future applications in photonics will be a priority. In addition ultra-fast pulsed laser deposition can be used to create nanopartilces and mechanisms affecting the growth of these materials will be studied. The project therefore falls into two priority areas: photon science and nanotechnology. Outcomes in addition to new knowledge will include materials and processes with commercial potential.Read moreRead less
Probing the Interface Between Polymeric Photonic Materials and Biology. This application provides a basis for Professor A. B. Holmes to develop a collaboration between the University of Melbourne (within the Bio21 Institute initiative) and CSIRO Division of Molecular Science to prepare novel plastics for electronics applications (lap top displays, transistors and solar cells) and to make specialised macromolecules for studying the way in which biological molecules may be made to recognise other ....Probing the Interface Between Polymeric Photonic Materials and Biology. This application provides a basis for Professor A. B. Holmes to develop a collaboration between the University of Melbourne (within the Bio21 Institute initiative) and CSIRO Division of Molecular Science to prepare novel plastics for electronics applications (lap top displays, transistors and solar cells) and to make specialised macromolecules for studying the way in which biological molecules may be made to recognise other molecules and thus change their function. It is envisaged that the multidisciplinary research collaboration will lead to commercial opportunities in "plastic electronics" and in human health such as the control of cancer and infectious diseases.Read moreRead less
Advanced Molecular Nanomaterials. The design and construction of advanced nanomaterials is a key step in the push towards smarter and more efficient high-level technologies. Here we mount a major research program into the strategic assembly of molecular nanomaterials that have entirely new and highly useful properties. This innovative work will lead to important fundamental advances in nanoscience and will forge deep understandings of how materials properties relate to nanoscale structure. Th ....Advanced Molecular Nanomaterials. The design and construction of advanced nanomaterials is a key step in the push towards smarter and more efficient high-level technologies. Here we mount a major research program into the strategic assembly of molecular nanomaterials that have entirely new and highly useful properties. This innovative work will lead to important fundamental advances in nanoscience and will forge deep understandings of how materials properties relate to nanoscale structure. These advances will spur a wide range of important new technologies, with application of the materials in electronics, photonics, molecular sensing, drug synthesis and purification, clean energy and the controlled release of agrochemicals and pharmaceuticals.Read moreRead less
Molecular control of apoptosis and protein homeostasis. A million cells are produced every second by cell division. At the same time a million cells commit suicide by a process called apoptosis. When cells fail to die when they should they can develop into cancers. In heart attacks, stroke and neurodegenerative diseases, many cells appear to activate their self destruct mechanism to die unnecessarily. Drugs that can cause cancer cells to kill themselves, or drugs that prevent cells dying when th ....Molecular control of apoptosis and protein homeostasis. A million cells are produced every second by cell division. At the same time a million cells commit suicide by a process called apoptosis. When cells fail to die when they should they can develop into cancers. In heart attacks, stroke and neurodegenerative diseases, many cells appear to activate their self destruct mechanism to die unnecessarily. Drugs that can cause cancer cells to kill themselves, or drugs that prevent cells dying when they shouldn't, would make a major impact on many important diseases. Understanding the molecular mechanisms of cell death is the first step towards developing these drugs.Read moreRead less