Defining The Clinical Role Of Topiramate In The Treatment Of Alcohol Dependence In Australia
Funder
National Health and Medical Research Council
Funding Amount
$718,836.00
Summary
We urgently require new strategies for the treatment of alcohol dependence. The effectiveness of currently approved alcohol medications is limited. Emerging data suggests that topiramate has robust effectiveness and that better medicine selection is possible for patients based on their genotype. We propose to conduct a double-blind randomised controlled trial to examine the clinical and cost effectiveness of topiramate using a genetically based personalised approach.
Reducing The Burden Of Alcohol And Other Drug Use In Australia
Funder
National Health and Medical Research Council
Funding Amount
$250,805.00
Summary
Innovative research undertaken during the Fellowship program will provide new evidence of how best to respond to alcohol and other drug use. Partnerships with policymakers will ensure this evidence underpins Australian alcohol and other drug policy.
The Relationship Between Accident Culpability And Drug Presence In Blood Samples Taken From Persons Injured In Motor Vehicle Collisions.
Funder
National Health and Medical Research Council
Funding Amount
$200,721.00
Summary
This project aims to determine the incidence of drugs in blood samples taken under the Victorian Road Safety Act 1986 from drivers involved in non-fatal collisions, the relative importance of illicit drugs, legal drugs used as prescribed, and legal drugs misused by drivers in non-fatal collisions by examining driver culpability in these accidents.
Quantifying The Predictors And Risks Of Problematic Alcohol Use
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
This Fellowship will identify the health outcomes, pathways to disability and death, and risk and protective factors for these harms among people with alcohol problems. Projects will include a longitudinal study of people with existing alcohol problems, a longitudinal study of adolescent emerging alcohol consumers, and a field study of alcohol problems in night-time entertainment areas. Findings will inform standardised alcohol screening and intervention and expansion of alcohol treatment.
A Randomised Controlled Trial Of N-acetylcysteine For The Treatment Of Alcohol Use Disorder
Funder
National Health and Medical Research Council
Funding Amount
$1,294,923.00
Summary
We urgently require new treatment strategies. Alcohol misuse is a leading cause of preventable death yet treatment options are limited. We will undertake the first human trial of N-acetylcysteine (NAC) for the management of alcohol use disorder (NAC-AUD). The NAC-AUD project will evaluate the efficacy and cost-efficacy of NAC to reduce alcohol consumption. The results will generate high level clinical evidence for a safe new treatment for a common life threatening disease.
Parental Supply Of Alcohol To Children: Associations With Early Adult Health – “binge” Drinking, Alcohol-related Harms, Aggression, And Alcohol Use Disorders
Funder
National Health and Medical Research Council
Funding Amount
$1,143,477.00
Summary
We will investigate of the impacts of parental supply of alcohol between 13-18 years, on early adult alcohol use (19-23 years). We will follow an existing cohort of ~1,810 parent-child dyads, and assess the development of alcohol use, disorders, harms and aggression. We will investigate the impacts of: parental supply of sips vs drinks; supervised vs unsupervised supply; and modifying effects of contexts of supply and mediators (such as peer, child factors, etc.) controlling for confounders.
Reducing The Burden Of Disease Due To Hazardous Alcohol Consumption
Funder
National Health and Medical Research Council
Funding Amount
$652,765.00
Summary
I am a behavioural scientist interested in the causes and prevention of hazardous alcohol consumption. I propose a program of research examining methods in behavioural science, risk factors for hazardous drinking, the development and evaluation of interventions to reduce hazardous drinking, and the evaluation of policies affecting the supply and promotion of alcohol. I lead a research team with strong collaborations with leading scientists in Australia and other countries.
Resilience In Individuals And Families Coping With The Impacts Of Alcohol Related Injuries In Remote Indigenous Communities: A Program Of Mixed Method Research
Funder
National Health and Medical Research Council
Funding Amount
$316,449.00
Summary
Alcohol Management Plans (AMPs) implemented by the Queensland Government a decade ago (2002-03), primarily to control alcohol availability in Indigenous communities, are currently under review. AMPs seemed to have a number of positive effects on injury rates related to alcohol use, however a paucity of rigorous data related to injuries is currently available. An in-depth study of alcohol related injury and resilience linked to alcohol injuries in four Indigenous communities will be conducted.