Special Research Initiatives - Grant ID: SR0354576
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. ....Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. Recognising these advances, this initiative focuses on harnessing Australia's capacity and potential in the use of spatially based methods and theories and brings researchers together in collaboration across a number of fields. Read moreRead less
ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial ....ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial concepts into statistical analysis and modelling, powerful visualisation of information, and the building spatial decision support systems, to provide an improved evidence base and better informed decision-making to address the significant challenges facing Australia's people and its places.Read moreRead less
Encoding Interactions and Printability into Hairy Colloidal Biomaterials. Printing mixtures of live cells and biomaterials (or 'BioInks') to make bespoke engineered tissues has the potential to enable personalised platforms for therapeutic discovery and organ replacement. Using a novel high throughput approach to materials synthesis, BioInk design and process optimisation, this project aims to discover new biomaterials and printing nozzles to help realise this potential. It will produce new insi ....Encoding Interactions and Printability into Hairy Colloidal Biomaterials. Printing mixtures of live cells and biomaterials (or 'BioInks') to make bespoke engineered tissues has the potential to enable personalised platforms for therapeutic discovery and organ replacement. Using a novel high throughput approach to materials synthesis, BioInk design and process optimisation, this project aims to discover new biomaterials and printing nozzles to help realise this potential. It will produce new insights in colloid science, cell-laden biomaterials design, and BioInk processing. Structure-property-function guides for colloid-based BioInks and quality-assured bioprinting as outcomes represent significant benefits for researchers and industries alike engaged in biofabrication, cell therapy and biotherapeutics.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100119
Funder
Australian Research Council
Funding Amount
$424,607.00
Summary
Manipulation of non-wetting droplets for cell culture. We have recently discovered an innovative and interdisciplinary approach for manipulating non-wetting droplets called “liquid marbles” as a platform for three-dimensional cell culture. This project aims to elucidate the fundamental physics underpinning the electrostatic handling concept of this platform technology. The project is expected to deliver an inexpensive but sophisticated cell culture platform that is well-suited for high-throughpu ....Manipulation of non-wetting droplets for cell culture. We have recently discovered an innovative and interdisciplinary approach for manipulating non-wetting droplets called “liquid marbles” as a platform for three-dimensional cell culture. This project aims to elucidate the fundamental physics underpinning the electrostatic handling concept of this platform technology. The project is expected to deliver an inexpensive but sophisticated cell culture platform that is well-suited for high-throughput drug screening and preparing cells for implantation therapy. Significant benefits for end users in pharmaceutical industry, life sciences research and hospitals are expected from the project and the application of the developed technology.Read moreRead less
Establishing Design Principles Of Polymers For Intracellular Delivery . Engineered polymers have played a central role in the field of bionanotechnology by enabling targeted nanoscale cell interactions. Progress in the field of intracellular delivery is currently affected by a major bottleneck due to the absence of effective polymers that is applicable across the range of bimolecular cargoes. In essence depending on the type of cargo: DNA, RNA or protien, the polymer needs programmability. The l ....Establishing Design Principles Of Polymers For Intracellular Delivery . Engineered polymers have played a central role in the field of bionanotechnology by enabling targeted nanoscale cell interactions. Progress in the field of intracellular delivery is currently affected by a major bottleneck due to the absence of effective polymers that is applicable across the range of bimolecular cargoes. In essence depending on the type of cargo: DNA, RNA or protien, the polymer needs programmability. The limited tunability of traditional polymers agents makes them unsuitable for this particular application. The multidisciplinary project addresses this significant problem by engineering novel sequences of defined polymer based nanoscale agents to achieve efficient delivery in cells.Read moreRead less
Special Research Initiatives - Grant ID: SR120300015
Funder
Australian Research Council
Funding Amount
$16,000,000.00
Summary
The Science of Learning Research Centre. In this innovative new Centre, researchers in education, neuroscience and cognitive psychology will work together with teachers to understand the learning process. This collaboration will establish new criteria to assess the impact of different types of learning and strategies to inform teaching practices of benefit to all Australians.
Unpacking the immune system with applied mathematics. This project aims to model immune interactions across cells and structures spanning scales of nanometres to millimetres. It expects to develop innovative mathematical insights, improve our understanding of immunology, and consolidate collaborations with top American and European laboratories and groups. Expected outcomes include cutting-edge techniques for multiscale biological modelling and improved prediction and analysis of immune dynami ....Unpacking the immune system with applied mathematics. This project aims to model immune interactions across cells and structures spanning scales of nanometres to millimetres. It expects to develop innovative mathematical insights, improve our understanding of immunology, and consolidate collaborations with top American and European laboratories and groups. Expected outcomes include cutting-edge techniques for multiscale biological modelling and improved prediction and analysis of immune dynamics. The project should provide benefits to industries where highly organised behaviours are important, for example those interested in robot swarming, optimal transportation, and epidemic management. It should also benefit Australian students and researchers with novel overseas training opportunities.Read moreRead less
Understanding the properties of layered nanostructures using in-situ TEM. This project aims to support the practical applications of layered nanostructure-based devices and systems. The development of layered chalcogenide nanostructures is a global research focus due to their potential applications in the energy sector. However, their structure–property link is unclear due to the lack of direct correlation between their structure and properties. This project aims to establish the intrinsic struc ....Understanding the properties of layered nanostructures using in-situ TEM. This project aims to support the practical applications of layered nanostructure-based devices and systems. The development of layered chalcogenide nanostructures is a global research focus due to their potential applications in the energy sector. However, their structure–property link is unclear due to the lack of direct correlation between their structure and properties. This project aims to establish the intrinsic structure–property link by closely correlating the structure (and structural variations) and properties (and varied properties) simultaneously determined from individual nanostructures inside a transmission electron microscope. Expected project outcomes may advance the knowledge base, and provide guidelines for the development of nanostructure-based devices for their high-performance applications, especially in the energy sector.Read moreRead less
Strengthening urban slum upgrading and urban governance in cities in Southeast Asia. 1. Improve the approach to evaluating the impact of slum upgrading in building institutional capacity, and thereby, on the longer-term continuity of poverty reduction for poor communities. These lessons can be applied in impoverished settlements in developed and developing countries;
2. Enhance best practice in planning upgrading projects and design of governance frameworks. These lessons can be applied throu ....Strengthening urban slum upgrading and urban governance in cities in Southeast Asia. 1. Improve the approach to evaluating the impact of slum upgrading in building institutional capacity, and thereby, on the longer-term continuity of poverty reduction for poor communities. These lessons can be applied in impoverished settlements in developed and developing countries;
2. Enhance best practice in planning upgrading projects and design of governance frameworks. These lessons can be applied throughout Asia - a region to which Australia is closely linked;
3. Make a substantial contribution to scholarly literature on urban upgrading and governance;
4. Strengthen international linkages between Australian researchers and key scholars in the USA, Canada, Philippines, Vietnam and Indonesia.
Read moreRead less
Promoting new reaction pathways with nonequilibrium flow. This project aims to develop a fundamental molecular level understanding of flow-induced physical and chemical reactions in liquids. Nonequilibrium molecular dynamics simulations will be used to gain insight into the mechanisms that promote reactions under shear, and how these are related to molecular structure and fluid composition. New relationships for determination of rate constants of reactions in nonequilibrium systems will also be ....Promoting new reaction pathways with nonequilibrium flow. This project aims to develop a fundamental molecular level understanding of flow-induced physical and chemical reactions in liquids. Nonequilibrium molecular dynamics simulations will be used to gain insight into the mechanisms that promote reactions under shear, and how these are related to molecular structure and fluid composition. New relationships for determination of rate constants of reactions in nonequilibrium systems will also be developed and tested. It is expected that this knowledge will enhance the capacity to control and promote reactions. This is significant for advancement of many technologies, from development of new synthetic pathways and products, to design of lubricants that can withstand extreme strain rates.Read moreRead less