CD4+CD8β+ Double-positive T-cell Regulation Of CD8 T-cell Responses
Funder
National Health and Medical Research Council
Funding Amount
$430,983.00
Summary
T-cells are a type of white blood cell that play an essential role in the immune system. CD4+CD8+ Double-Positive (DP) T-cells are a rare and poorly defined T-cell subset associated with skin disease - however their function and subsequently their contribution to disease is not known. Our preliminary data suggest that these DP cells may regulate the function of other immune populations in the skin. This project aims to deliver key insights into DP cells and their role in skin disease.