Development of an ultrasensitive assay for human prion proteins. The aim of this work is to enable the detection of prion proteins in human blood and other tissues. The assay system to be developed will detect much lower levels of these disease-causing proteins than is possible at present; it will be more rapid and will measure prion protein levels more accurately than existing assays. The outcome of the work is expected to facilitate the production and certification of prion-free blood and bl ....Development of an ultrasensitive assay for human prion proteins. The aim of this work is to enable the detection of prion proteins in human blood and other tissues. The assay system to be developed will detect much lower levels of these disease-causing proteins than is possible at present; it will be more rapid and will measure prion protein levels more accurately than existing assays. The outcome of the work is expected to facilitate the production and certification of prion-free blood and blood products. Prions cause Bovine Spongiform Encaphalopathy and Creutzfeld Jacob Disease and attempts to control of these diseases would be greatly abetted by an optimal test for the disease-causing agent.Read moreRead less
A high speed, high fidelity 3D printer for fabricating microfluidic devices. This project aims to develop a novel 3D printer offering the highest resolution available and fastest printing speed for the single-step manufacturing of complex microfluidic devices. New resins developed to exploit the inert liquid interface layer printing approach will provide unprecedented capability to create micron sized channels interconnected in 3D space and fabricate Lab-on-a-Chip systems that cannot be generate ....A high speed, high fidelity 3D printer for fabricating microfluidic devices. This project aims to develop a novel 3D printer offering the highest resolution available and fastest printing speed for the single-step manufacturing of complex microfluidic devices. New resins developed to exploit the inert liquid interface layer printing approach will provide unprecedented capability to create micron sized channels interconnected in 3D space and fabricate Lab-on-a-Chip systems that cannot be generated by any current fabrication approach. This novel high speed, high fidelity 3D printer and the new resins to be developed are expected to lead to more effective manufacturing approaches for portable chemical devices and to promote complex chemical analysis into the knowledge immediacy culture of today.Read moreRead less
New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses ....New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses with data libraries to generate precise molecular identification. The outcome is expected to help monitor adulteration of oils and maintain the high quality standards of Australian produce.Read moreRead less
The measurement and prediction of police interviewing performance and the dissemination of good practice through a distributive workplace learning system. This research aims to develop the first ever standardised measures of police interviewers' performance, focusing on interviews about sexual offences. Standardised measures are essential for quality control evaluation, identifying training needs, assigning workload, predicting case outcome and benchmarking organisation capabilities. By improvin ....The measurement and prediction of police interviewing performance and the dissemination of good practice through a distributive workplace learning system. This research aims to develop the first ever standardised measures of police interviewers' performance, focusing on interviews about sexual offences. Standardised measures are essential for quality control evaluation, identifying training needs, assigning workload, predicting case outcome and benchmarking organisation capabilities. By improving the quality of police interviews about sexual offences, this research will improve the reporting, prosecution and conviction rates of sexual offences, which will have a deterrent effect on potential offenders. Further, this research will reduce the stress of witnesses and suspects involved in the legal process and reduce burnout of police interviewers by increasing competency and job satisfaction.Read moreRead less
A longitudinal study of language learning to assess early intervention outcomes in pre-school children with impaired hearing. Overseas research suggests that young children with impaired hearing and normal non-verbal cognition can develop normal language if hearing aid fitting and intervention occur before 6 months of age. Australian studies show considerable language delays in most hearing-impaired children of primary-school age. We will study the spoken language learning of hearing-impaired ....A longitudinal study of language learning to assess early intervention outcomes in pre-school children with impaired hearing. Overseas research suggests that young children with impaired hearing and normal non-verbal cognition can develop normal language if hearing aid fitting and intervention occur before 6 months of age. Australian studies show considerable language delays in most hearing-impaired children of primary-school age. We will study the spoken language learning of hearing-impaired children up to age 6 years in Victoria. The project will investigate crucial factors in achieving normal language learning in hard-of-hearing children and the role of early intervention. Normal language outcomes would enhance the educational and career prospects of hearing-impaired children and result in community cost savings.
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Improving the competency of police officers in conducting investigative interviews of children. The current research program aims to identify factors that promote and sustain competent police interviewing of children. Although 'best-practice' guidelines in investigative interviewing have been developed, these guidelines are under-utilised by police officers in practice. Research is therefore needed to identify barriers to the implementation of these 'best-practice' guidelines and to test interve ....Improving the competency of police officers in conducting investigative interviews of children. The current research program aims to identify factors that promote and sustain competent police interviewing of children. Although 'best-practice' guidelines in investigative interviewing have been developed, these guidelines are under-utilised by police officers in practice. Research is therefore needed to identify barriers to the implementation of these 'best-practice' guidelines and to test interventions designed to improve their uptake. The expected outcome of this project is the development of interventions that will improve the quality of police training in investigative interviewing. This will increase the quality of evidence obtained from children, especially those who are victims of child abuse.Read moreRead less
Conceiving Connections: Increasing industry viability through analysis of audience responses to dance performance. The development of audiences is identified by the Australian dance industry as vital to the future of the sector. The current project will investigate how audiences respond to highly evolved dance-works. It will explore the kinds of meaning communicated by such works, and the value assigned to them by tutored and untutored audiences. Methods for enhancing audience engagement will be ....Conceiving Connections: Increasing industry viability through analysis of audience responses to dance performance. The development of audiences is identified by the Australian dance industry as vital to the future of the sector. The current project will investigate how audiences respond to highly evolved dance-works. It will explore the kinds of meaning communicated by such works, and the value assigned to them by tutored and untutored audiences. Methods for enhancing audience engagement will be tested through studies in both metropolitan and regional centres. Dance-scholars, artists and cognitive psychologists collaborate with three industry partners to identify and address significant concerns for artists, presenters, advocates and funding bodies, and to train postgraduate reserachers in inter-disciplinary modes.Read moreRead less
Assessment and treatment software for developmental disabilities based on neuroscientific theories for information processing. Performance on tasks relating to fluency of reading, language and sensory motor integration is impaired to some degree in children with dyslexia, ADHD, autism, and intellectual disability (ID). Thus our aim is to develop and test, to the point of commercial release, software for assessment of visual and auditory performance relating to social, language and literacy diff ....Assessment and treatment software for developmental disabilities based on neuroscientific theories for information processing. Performance on tasks relating to fluency of reading, language and sensory motor integration is impaired to some degree in children with dyslexia, ADHD, autism, and intellectual disability (ID). Thus our aim is to develop and test, to the point of commercial release, software for assessment of visual and auditory performance relating to social, language and literacy difficulties for young children. Furthermore software which aims to train attention and improve speed of visual object recognition will be developed and if effective as a treatment to improve reading and social interactions in ID, will be released by Fildes Foundation as an easily accessible multi-media based home/school therapy.Read moreRead less
Attention and hazard perception while driving: how experts see the scene. All drivers have 'drifted-off' or failed to see something that was clearly in view, yet trained expert drivers appear to rarely experience this. This project aims to understand in both 'normal' drivers and expert drivers, attentional mechanisms that control distraction and the perception of hazards, which is critical to road safety and young driver training.