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Research Topic : Immunity
Scheme : Research Fellowships
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Cellular Immunology (9)
Immunology not elsewhere classified (5)
Structural Biology (incl. Macromolecular Modelling) (4)
Innate Immunity (2)
Medical Parasitology (2)
Autoimmunity (1)
Clinical chemistry (incl. diagnostics) (1)
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  • Funded Activities (31)
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  • Funded Activity

    Research Fellowship To Study HIV Vaccines

    Funder
    National Health and Medical Research Council
    Funding Amount
    $826,854.00
    Summary
    I am an infectious diseases physician and virologist/immunologist focused on developing and testing vaccines against the AIDS virus. I intend to achieve this by advancing novel vaccine concepts that stimulate broad and potent immunity and evaluating these vaccines in rigorous laboratory models and then moving them towards clinical trials.
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    Funded Activity

    Understanding Universal Immunity To Influenza Viruses

    Funder
    National Health and Medical Research Council
    Funding Amount
    $687,975.00
    Summary
    A/Prof Kedzierska’s work combines cutting-edge basic research with unique clinical studies to define how to generate protective immunity against the pandemic and newly emerged influenza viruses. This research will identify key factors that drive the severe and fatal influenza disease in high-risk groups, including the young, elderly, pregnant women and Indigenous Austraians. Findings on the optimal human immunity to influenza viruses will be applicable to other infectious diseases and cancers.
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    Funded Activity

    Mapping The Molecular Blueprint For Immune Cell Differentitation

    Funder
    National Health and Medical Research Council
    Funding Amount
    $753,300.00
    Summary
    Killer T cells are white blood cells that are key for helping control virus infections and in the recognition and elimination of cells that have become cancerous. This proposal aims to identify novel molecular mechanisms that control the ability of killer T cells to mediate their antiviral and anti-cancer functions. This will provide molecular targets for possible clinical interventions designed to either promote immunity (vaccination) or limit damage caused by T cell responses that target self
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    Funded Activity

    Delineating Immune Circuits For Innate And Adaptive Immune Protection

    Funder
    National Health and Medical Research Council
    Funding Amount
    $876,005.00
    Summary
    The immune system provides the essential frame-work to protect us against infection, disease and to heal tissues after trauma. This is achieved by a complex but elegant network of different types of white blood cells. Understanding the molecular wiring of these cells will provides fundamental insights to how the body fights pathogen infections and cancer and lays the foundation to therapeutic approaches to vaccination and disease treatments.
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    Funded Activity

    Structural Biology Of Infection And Immunity

    Funder
    National Health and Medical Research Council
    Funding Amount
    $664,584.00
    Summary
    I am a biochemist focussed on understanding how the structures of proteins determine their functions. I intend to apply this understanding to medically relevant questions by working collaboratively and using a range of complementary structural, computational and cell biology techniques. In particular, I will focus on proteins involved in infection and immunity, to understand how they work, and contribute to the development of drugs and vaccines.
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    Funded Activity

    Defining The Cellular Interactions For Initiation And Maintenance Of Immunity To Intracellular Pathogens

    Funder
    National Health and Medical Research Council
    Funding Amount
    $863,413.00
    Summary
    This immune system provides our body’s defense against invading organisms like viruses, preventing disease and maintaining health. Immunity involves the interaction of several different cell types that together form arsenals tailored to combat each different infection. Professor Heath will investigate how cells of the immune system orchestrate effective immune responses to viral infections and malaria. He will use this understanding to design novel approaches to vaccination.
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    Funded Activity

    Immunoregulation, Innate And Adaptive Immunity, Viral Immunology, Ocular Immunology, Immunotherapy

    Funder
    National Health and Medical Research Council
    Funding Amount
    $880,454.00
    Summary
    The focus on our research is to understand how the immune system responds to viral challenges and how viruses attempt to counteract immune responses. We focus on systemic disease, as well as disease that involve the eye. Understanding how immune responses are regulated will allows us to develop improved therapies
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    Funded Activity

    Research Fellowship

    Funder
    National Health and Medical Research Council
    Funding Amount
    $814,893.00
    Summary
    This an integrated program of basic research on antigen discovery and immune mechanisms, and preclinical research on novel vaccine platforms, formulations or delivery systems for the rational design and clinical testing of a next generation vaccine against malaria. This interdisciplinary research fosters strong national and international links and offers the potential for significant economic benefit to Australia.
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    Funded Activity

    Inflammasome Function In Protection Against Infectious Disease And Autoimmunity

    Funder
    National Health and Medical Research Council
    Funding Amount
    $631,010.00
    Summary
    Inflammation, characterised by swelling, heat, pain and redness, is a normal response to injury and infection. Many human diseases such as gout, athersclerosis, diabetes and Alzheimer’s disease involve some inflammation, mediated through a common pathway termed the inflammasome. This project will investigate the proteins involved in this pathway and how they interact in their normal role of combatting infections, as well as a possible defect in this pathway in autoimmune patients.
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    Funded Activity

    Research Fellowship - Grant ID:637315

    Funder
    National Health and Medical Research Council
    Funding Amount
    $170,688.00
    Summary
    I am a public health physician and medical parasitologist determining the mechanism of clinical immunity to malaria, and working on the development of vaccines and therapies against malaria.
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    Showing 1-10 of 31 Funded Activites

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