New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput anal ....New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput analytical cultivation, molecular networking, and chemical and biological analyses, expected outcomes include an enhanced ability to explore and exploit valuable chemistry hidden within microbial genomes, leading to the discovery of new classes of natural antiparasitic to safeguard livestock.
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The big flood: will it happen again? If we could better predict the frequency of extreme flood events, would we be better prepared to safeguard human lives and settlements? This project provides a time-line of flood activity in the south east Queensland region extending back thousands of years using state-of-the-art dating techniques and seeks to identifiy those settlements most at risk.
Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laborator ....Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laboratory techniques and DNA identification methods to provide a template for determining ground water diversity and food web dynamics throughout Australia. This project will lead to a better understanding of how to manage ground water in a sustainable manner.Read moreRead less
Growing a sustainable new molecular resource. This project will provide access to a unique and unexplored Australian molecular resource pre-programmed by evolution for therapeutic potential. These discoveries will enable important biomedical research and advance the development of new improved drugs that treat a diverse array of human diseases and illness.
Optimising seed sourcing for effective ecological restoration. This project aims to address the sourcing of native seed for ecological restoration under global change. The great demand for native seed to deliver ecological restoration provides a clear need and responsibility to use this seed as efficiently as possible. This project expects to develop detailed new knowledge that links plant and environmental genomics, plant physiology, seed and soil biology in embedded experiments at post-mining ....Optimising seed sourcing for effective ecological restoration. This project aims to address the sourcing of native seed for ecological restoration under global change. The great demand for native seed to deliver ecological restoration provides a clear need and responsibility to use this seed as efficiently as possible. This project expects to develop detailed new knowledge that links plant and environmental genomics, plant physiology, seed and soil biology in embedded experiments at post-mining rehabilitation sites. Expected outcomes include clear industry guidelines that refine seed sourcing strategies for ecological restoration for current and future climates. This should provide significant benefits for improved ecological restoration outcomes when using native seed today and into the future.Read moreRead less
Mechanism of synergy of ingredients in natural products and functional foods. Synergism is the interaction of two substances to produce an effect larger than the sum of the separate effects. This project aims to determine the basic biological mechanisms or molecular targets by which the synergy is occurring and to identify the bioactive compounds involved. Understanding how synergism works should help us to identify other synergistic compounds, allowing optimization of products for better effica ....Mechanism of synergy of ingredients in natural products and functional foods. Synergism is the interaction of two substances to produce an effect larger than the sum of the separate effects. This project aims to determine the basic biological mechanisms or molecular targets by which the synergy is occurring and to identify the bioactive compounds involved. Understanding how synergism works should help us to identify other synergistic compounds, allowing optimization of products for better efficacy and quality, and leading to new products that have a significant market advantage over currently available products. This project will help to develop improved natural products that could push this industry advantage further.Read moreRead less
Collaborative science for monitoring of Northern Territory marine megafauna. The project’s aim is to map population connectivity and critical habitat for coastal marine megafauna in remote northern Australian waters, providing a more informed scientific base for biodiversity monitoring and management. The project will employ cutting edge methods in genetics and movement ecology and unite Indigenous rangers with marine national park managers and scientists. Expected outcomes include enhanced capa ....Collaborative science for monitoring of Northern Territory marine megafauna. The project’s aim is to map population connectivity and critical habitat for coastal marine megafauna in remote northern Australian waters, providing a more informed scientific base for biodiversity monitoring and management. The project will employ cutting edge methods in genetics and movement ecology and unite Indigenous rangers with marine national park managers and scientists. Expected outcomes include enhanced capacity for monitoring and conservation planning and new partnerships that will improve research capacity in remote environments. Benefits include environmental management led by Indigenous Traditional Owners, sea rangers and marine park managers, and conservation benefits to coastal dolphin and sea turtle species.Read moreRead less
Managing the existing and emerging threats from coastal flow slides. This project aims to develop the first management strategies for coastal flow slides. This project expects to generate new knowledge on how flow slides are triggered, propagate inland and undermine structures. Expected outcomes include globally applicable novel models and management approaches developed by an interdisciplinary team of coastal and geotechnical engineers and coastal geomorphologist using innovative data. This is ....Managing the existing and emerging threats from coastal flow slides. This project aims to develop the first management strategies for coastal flow slides. This project expects to generate new knowledge on how flow slides are triggered, propagate inland and undermine structures. Expected outcomes include globally applicable novel models and management approaches developed by an interdisciplinary team of coastal and geotechnical engineers and coastal geomorphologist using innovative data. This is likely to provide significant benefits for planning and managing structures along coasts and bays against destructive flow slides. The project will enable the design and implementation of coastal works to protect existing structures against flow slides risks emerging with rising sea level.Read moreRead less
Advances in real-time satellite monitoring of flow in rivers and estuaries. This project plans to improve the monitoring of our waterways by developing a novel moving drifter system that takes flow and water quality measurements along the pathlines of the drifters. One of the key challenges for Australian water management lies in monitoring and managing rivers and estuaries effectively over large geographical areas. Traditionally, instrumentation at stationary points has been used for such monit ....Advances in real-time satellite monitoring of flow in rivers and estuaries. This project plans to improve the monitoring of our waterways by developing a novel moving drifter system that takes flow and water quality measurements along the pathlines of the drifters. One of the key challenges for Australian water management lies in monitoring and managing rivers and estuaries effectively over large geographical areas. Traditionally, instrumentation at stationary points has been used for such monitoring, under the simplifying assumption that a single point adequately represents a very large region of water. By contrast, the Real-Time Flow Logging of Water (RT-FLOW) system expects to provide information from large regions of our waterways, providing stakeholders with more information to enable them to better manage issues including storm surge and erosion. The project also aims to provide improved validation of hydrodynamic models.Read moreRead less
Coral resilience and the optimal management of biodiversity. This project aims to examine the resilience of coral biodiversity to disturbances and build on recently developed genomic resources to explore the genotypic traits that confer thermal tolerance. The project will research how coral biodiversity responds to climatic disturbances; the potential for acclimation and adaptation; and the best ways to monitor, manage and restore biodiversity. The project is expected to generate tangible outcom ....Coral resilience and the optimal management of biodiversity. This project aims to examine the resilience of coral biodiversity to disturbances and build on recently developed genomic resources to explore the genotypic traits that confer thermal tolerance. The project will research how coral biodiversity responds to climatic disturbances; the potential for acclimation and adaptation; and the best ways to monitor, manage and restore biodiversity. The project is expected to generate tangible outcomes and strategies to optimise the management of Australia’s coral biodiversity while engaging the public through museum-based outreach, in collaboration with government, regulatory sectors and an industry group. Read moreRead less