Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100001
Funder
Australian Research Council
Funding Amount
$875,000.00
Summary
A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected out ....A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected outcomes to include the generation of new knowledge of major biological systems, including the immune system and the nervous system. This will provide significant benefits to fundamental interdisciplinary research into immunology, infectious disease, neuroscience, mechanobiology and engineering.Read moreRead less
Modelling human brain development with stem cells and biomaterials. With limited resources to directly study and advance our understanding of human neural development, this
proposal will establish models of 4 key stages. Employing innovative, interdisciplinary approaches, biomaterials will be fabricated to provide structural and chemical support for human stem cells during: (i) neural induction, (ii) specification into neuronal progenitor subpopulations, (iii) neuronal maturation and integration ....Modelling human brain development with stem cells and biomaterials. With limited resources to directly study and advance our understanding of human neural development, this
proposal will establish models of 4 key stages. Employing innovative, interdisciplinary approaches, biomaterials will be fabricated to provide structural and chemical support for human stem cells during: (i) neural induction, (ii) specification into neuronal progenitor subpopulations, (iii) neuronal maturation and integration into complex neural networks as well as, (iv) the organisation of neurons into larger 3-dimensional brain structures, namely folding of the human cortex. Further, biomaterials developed here have commercialisation potential, targeted at standardizing the culturing of human stem cells to defined neural populations.
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Engineering a technology platform for organoids. Protein delivery technologies hold great potential to improve organoids (miniature organs used as in vitro models), allowing a deep understanding of development. However, current limitations must be overcome - particularly cost, precision, and efficacy. This project will engineer delivery materials to improve the efficacy of organoids, allowing control over the location and timing of protein delivery. Outcomes will include a technology platform o ....Engineering a technology platform for organoids. Protein delivery technologies hold great potential to improve organoids (miniature organs used as in vitro models), allowing a deep understanding of development. However, current limitations must be overcome - particularly cost, precision, and efficacy. This project will engineer delivery materials to improve the efficacy of organoids, allowing control over the location and timing of protein delivery. Outcomes will include a technology platform of immediate use in the agriculture sector and for animal model alternatives. The benefit will be widespread, ensuring the growth and sustainability of our health and agriculture sector. The project will increase public understanding of protein delivery technologies, aiding in technology adoption.Read moreRead less
Control of developmental switches by importin 5. Aims: This project will study a key molecular switch called IPO5, a protein that is required for cells and organs to form and function normally, and it will reveal how it works.
Significance: These experiments will provide the first complete description of how this molecular switch controls the behaviour of a cell across its lifespan. IPO5 is highly conserved, so these studies will be relevant to a wide range of animals.
Expected Outcomes: This k ....Control of developmental switches by importin 5. Aims: This project will study a key molecular switch called IPO5, a protein that is required for cells and organs to form and function normally, and it will reveal how it works.
Significance: These experiments will provide the first complete description of how this molecular switch controls the behaviour of a cell across its lifespan. IPO5 is highly conserved, so these studies will be relevant to a wide range of animals.
Expected Outcomes: This knowledge will reveal how IPO5 controls formation of sperm by revealing what other proteins it binds to and how this affects cell signaling and responses to the environment.
Benefits: This will provide information about potential interventions to control fertility or to repair abnormal cells.
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Coding of olfactory information in the piriform cortex. This project aims to understand how electrical activity in the primary olfactory (piriform) cortex enables mice to recognise and remember odours. By using optical recording techniques together with genetic tools, the project expects to generate new knowledge about how the mammalian brain builds internal representations of the external world. Specific outcomes of the project include new insights into the functional architecture of the pirifo ....Coding of olfactory information in the piriform cortex. This project aims to understand how electrical activity in the primary olfactory (piriform) cortex enables mice to recognise and remember odours. By using optical recording techniques together with genetic tools, the project expects to generate new knowledge about how the mammalian brain builds internal representations of the external world. Specific outcomes of the project include new insights into the functional architecture of the piriform cortex and fresh understanding of how olfactory information is encoded and stored in neural circuits. More broadly, the project aims to advance our understanding of how the brain works, with benefits for future improvements in artificial intelligence and brain-machine interfaces.Read moreRead less
Developing A Smart Farming Oriented Secure Data Infrastructure. Smart farming is the future of agriculture. However, recently the Federal Bureau of Investigation has issued a
warning that the lack of data privacy and cyber security mechanisms in the field runs a high risk of disaster. This
project aims to establish an innovative secure data infrastructure for smart farming including secure and automated smart farming supply-chain management. The deliverables of this project will include the cutt ....Developing A Smart Farming Oriented Secure Data Infrastructure. Smart farming is the future of agriculture. However, recently the Federal Bureau of Investigation has issued a
warning that the lack of data privacy and cyber security mechanisms in the field runs a high risk of disaster. This
project aims to establish an innovative secure data infrastructure for smart farming including secure and automated smart farming supply-chain management. The deliverables of this project will include the cutting-edge Blockchain based secure IoT data management and privacy-preserving smart contracts for smart farming supply-chain management. This data infrastructure will be the first of its kind which will lay a solid foundation for smart farming technology.Read moreRead less
MemberGuard: Protecting Machine Learning Privacy from Membership Inference. Machine Learning has become a core part of many real-world applications. However, machine learning models are vulnerable to membership inference attacks. In these attacks, an adversary can infer if a given data record has been part of the model's training data. In this project, the team aims to develop new techniques that can be used to counter these attacks, such as 1) new analytical models for membership leakage, 2) ne ....MemberGuard: Protecting Machine Learning Privacy from Membership Inference. Machine Learning has become a core part of many real-world applications. However, machine learning models are vulnerable to membership inference attacks. In these attacks, an adversary can infer if a given data record has been part of the model's training data. In this project, the team aims to develop new techniques that can be used to counter these attacks, such as 1) new analytical models for membership leakage, 2) new methods for susceptibility diagnosis, 3) new defences that leverage privacy and utility. Data-oriented services are estimated to be valuable assets in the future. These techniques can help Australia gain cutting edge advantage in machine learning security and privacy and protect its intellectual property on these services.Read moreRead less
DeepHoney: Automatic Honey Data Generation for Active Cyber Defence . This project aims to enhance the security of networks and information systems by empowering them with intelligent deception techniques to achieve proactive attack detection and defence. In recent times, the fictitious environment – honeypot designed by human experience becomes popular to attract attackers and capture their interactions. However, rules-based construction of honeypots fails in preserving the privacy, boosting th ....DeepHoney: Automatic Honey Data Generation for Active Cyber Defence . This project aims to enhance the security of networks and information systems by empowering them with intelligent deception techniques to achieve proactive attack detection and defence. In recent times, the fictitious environment – honeypot designed by human experience becomes popular to attract attackers and capture their interactions. However, rules-based construction of honeypots fails in preserving the privacy, boosting the attractiveness and evolving the system. The project expects to advance deep learning and yield novel DeepHoney technologies with associated publications and open-source software. This should benefit science, society, and the economy by building the next generation of active cyber defence systems. Read moreRead less
Privacy-preserving Biometrics based Authentication and Security. Password based authentication systems cannot verify genuine users. Biometric authentication can address this issue. However, the booming IoT applications and cloud computing require that the biometric authentication must be conducted in the privacy-protected setting in order to comply with privacy protection legal regulations. Latest reports show that current biometric authentication systems, under protected setting, exhibit poor ....Privacy-preserving Biometrics based Authentication and Security. Password based authentication systems cannot verify genuine users. Biometric authentication can address this issue. However, the booming IoT applications and cloud computing require that the biometric authentication must be conducted in the privacy-protected setting in order to comply with privacy protection legal regulations. Latest reports show that current biometric authentication systems, under protected setting, exhibit poor authentication performance, which is not commercially applicable. This project aims to investigate innovative solutions to this issue. The intended deliverables will include deep learning based biometric feature extractor, cancellable biometrics and cloud oriented biometrics security protocols. Read moreRead less
Attracting The Next Generation - Primary Industries Education Foundation Australia Membership 2022-2023
Funder
Fisheries Research and Development Corporation
Funding Amount
$52,550.00
Summary
Engaging with and educating the next generation is challenging and competitive, given the range of opportunities available to teachers and students in terms of topics, development opportunities and careers locally, nationally and globally.
Providing awareness, access and support to educators and students is critical to attracting and retaining people across fishing and aquaculture. Through curriculum aligned resources and aligned interventions, activities and experiences, FRDC can spar ....Engaging with and educating the next generation is challenging and competitive, given the range of opportunities available to teachers and students in terms of topics, development opportunities and careers locally, nationally and globally.
Providing awareness, access and support to educators and students is critical to attracting and retaining people across fishing and aquaculture. Through curriculum aligned resources and aligned interventions, activities and experiences, FRDC can spark the curiosity and also provide access to a range of people in fishing and aquaculture through partnering with PIEFA.
This project builds on the strong relationship with PIEFA to conduct research to understand the current level of engagement, barriers and opportunities to position fishing and aquaculture with students and educators. This research will position FRDC for success through utilisation of established, trusted channels and networks. Providing opportunities to showcase the wide variety careers through interactive activities and self directed learning provides the fishing and aquaculture community a direct connection with the next generation.
PIEFA provides a mechanism to showcase fishing and aquaculture, and food and fibre more broadly in Australian schools.
This includes accessing multiple platforms, newsletters, exclusive invitations to members meetings and PIEFA AGM. Invitation to 2023 PIEFA Conference and events. Objectives: 1. Understand and improve teacher awareness, confidence and knowledge to effectively implement food and fibre education in Australian schools 2. Utilise and leverage trusted, valued PIEFA networks and channels 3. Food and fibre education resources are accessible and are accessed by a growing number of Australian schools 4. Inform and engage with a national strategic framework that supports schools awareness and delivery of food and fibre education and careers 5. Food and fibre education initiatives and messages in the wider media and industry spheres are identified and shared between PIEFA and FRDC Read moreRead less