Multi-modal virtual microscopy for quantitative diagnostic pathology. This project will contribute to the next generation of virtual microscopy systems that provide innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of diagnostic pathology. These tools will especially contribute to the screening and diagnosis of cervical, lung and bladder cancer.
Enabling Automatic Graph Learning Pipelines with Limited Human Knowledge. This project aims to develop an automatic graph learning system for complex graph data analysis. Machine learning for graph data commonly requires significant human knowledge from both domain professionals as well as algorithm experts, rendering existing systems ineffective and unexplainable. This project expects to design novel graph learning techniques which automatically infer graph relations, learn graph models, adapts ....Enabling Automatic Graph Learning Pipelines with Limited Human Knowledge. This project aims to develop an automatic graph learning system for complex graph data analysis. Machine learning for graph data commonly requires significant human knowledge from both domain professionals as well as algorithm experts, rendering existing systems ineffective and unexplainable. This project expects to design novel graph learning techniques which automatically infer graph relations, learn graph models, adapts existing knowledge to new domains, and provide explanations to the graph learning system. The research results should provide benefit to governments and businesses in many critical applications, such as bioassay activity prediction, credit assessment, and drug discovery and vaccine development in response to the pandemic.Read moreRead less
Model checking Multi-Agent System and its applications. This research project directly addresses two of the Australian Government's four National Research Priorities: National Research Priorities 3 and 4. It will develop an enabling technology that is applicable to the development of safety-intensive and highly dependable software systems like medical equipment and airport controlling systems. The security protocol analysis technologies developed by this project can be useful for providing impro ....Model checking Multi-Agent System and its applications. This research project directly addresses two of the Australian Government's four National Research Priorities: National Research Priorities 3 and 4. It will develop an enabling technology that is applicable to the development of safety-intensive and highly dependable software systems like medical equipment and airport controlling systems. The security protocol analysis technologies developed by this project can be useful for providing improved ways of military operation flows, and for making Australian security communication systems more dependable.Read moreRead less
Imaging the foundation of the nervous system. This Project aims to understand the formation of the neural tube; a fundamental tissue structure that generates the brain and the spinal cord. Using interdisciplinary approaches and exploiting recent advances in transgenic and imaging technologies, the Project expects to reveal the complex interplay of molecular, cellular and mechanical processes that direct neural tissue formation and cell fate specification. Outcomes from the Project include knowle ....Imaging the foundation of the nervous system. This Project aims to understand the formation of the neural tube; a fundamental tissue structure that generates the brain and the spinal cord. Using interdisciplinary approaches and exploiting recent advances in transgenic and imaging technologies, the Project expects to reveal the complex interplay of molecular, cellular and mechanical processes that direct neural tissue formation and cell fate specification. Outcomes from the Project include knowledge of previously intractable developmental processes, training of future scientists and development of international collaborations. This should provide enhanced imaging capacity, a higher quality scientific workforce and position Australia at the forefront of developmental biology.
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The role of strong duality in computer vision. This project aims to undertake research in the fields of computer vision and optimization that will have a significant impact on the design of numerical algorithms for solving a wide range of problems in Computer Vision, Virtual Reality and Robotic Navigation. This project will advance understanding of a broad class of problems related to how computers interpret images. An expected outcome is the generation of novel mathematical theory and numerical ....The role of strong duality in computer vision. This project aims to undertake research in the fields of computer vision and optimization that will have a significant impact on the design of numerical algorithms for solving a wide range of problems in Computer Vision, Virtual Reality and Robotic Navigation. This project will advance understanding of a broad class of problems related to how computers interpret images. An expected outcome is the generation of novel mathematical theory and numerical algorithms capable of fundamentally changing the way problems relevant to a wide range of vision-related applications are solved. This should offer Australia a strong competitive advantage as a leader in scientific innovation in the areas of Computer Vision, Virtual Reality and Robotics and Autonomous Systems.Read moreRead less
A pictorial communication framework for inclusion. A picture can tell a thousand words; many people with an intellectual disability can only communicate with pictures and are otherwise isolated. This project will research how computers can understand and facilitate a rich pictorial communication between people and person to machine, thereby supporting inclusion. This will be achieved by inclusively co-designing with people with ID and members of the community: a) an audio-visual accessible searc ....A pictorial communication framework for inclusion. A picture can tell a thousand words; many people with an intellectual disability can only communicate with pictures and are otherwise isolated. This project will research how computers can understand and facilitate a rich pictorial communication between people and person to machine, thereby supporting inclusion. This will be achieved by inclusively co-designing with people with ID and members of the community: a) an audio-visual accessible search tool, b) a pictorial communication device, and c) a visual inclusive social network. These applications will inform future innovations for everyone, and allow citizens with ID to access online information, participate in community activities and be included in the workplace.Read moreRead less
Regulation of 3D Cell Migration by Microtubule-Dependent Processes. The overarching aim of this research is to elucidate the molecular mechanisms that cells use to move in 3D environments: a basic biological function essential to development and homeostasis. During these processes, cells interact with their surroundings where they translate biophysical forces into biochemical signals to adapt their shape to move. This requires distinct signalling, controlled in space and time, to regulate the cr ....Regulation of 3D Cell Migration by Microtubule-Dependent Processes. The overarching aim of this research is to elucidate the molecular mechanisms that cells use to move in 3D environments: a basic biological function essential to development and homeostasis. During these processes, cells interact with their surroundings where they translate biophysical forces into biochemical signals to adapt their shape to move. This requires distinct signalling, controlled in space and time, to regulate the crosstalk between organelles and the cytoskeleton. To date, the role of microtubules remains elusive. Using interdisciplinary approaches combining advanced imaging technology with novel cell biology methods, the project aims to uncover fundamental knowledge about how cells interact with their environment.Read moreRead less
Superhuman place recognition with a unified model of human visual processing and rodent spatial memory. Current robotic and personal navigation systems leave much to be desired; GPS only works in open outdoor areas, lasers are expensive and cameras are highly sensitive to changing environmental conditions. In contrast, nature has evolved superb navigation systems. This project aims to solve the challenging problem of place recognition, a key component of navigation, by modelling the visual recog ....Superhuman place recognition with a unified model of human visual processing and rodent spatial memory. Current robotic and personal navigation systems leave much to be desired; GPS only works in open outdoor areas, lasers are expensive and cameras are highly sensitive to changing environmental conditions. In contrast, nature has evolved superb navigation systems. This project aims to solve the challenging problem of place recognition, a key component of navigation, by modelling the visual recognition skills of humans and the rodent spatial memory system. This project looks to combine the best understood and most capable components of place recognition in nature to create a whole more capable than its parts, produce advances in robotic and personal navigation technology and lead to breakthroughs in understandings of the brain.Read moreRead less
Real-time Event Detection, Prediction, and Visualization for Emergency Response. This project proposes novel end-to-end methods for real-time recognition and prediction of real-world events, leading to timely response to emergencies such as disease outbreaks and natural disasters, as well as prevention of crime, security breaches and the like. It will develop new techniques to quickly detect and predict events by incorporating adaptive learning and probabilistic models, and address fusion and sc ....Real-time Event Detection, Prediction, and Visualization for Emergency Response. This project proposes novel end-to-end methods for real-time recognition and prediction of real-world events, leading to timely response to emergencies such as disease outbreaks and natural disasters, as well as prevention of crime, security breaches and the like. It will develop new techniques to quickly detect and predict events by incorporating adaptive learning and probabilistic models, and address fusion and scalability factors to handle vast collections of heterogeneous data. An event surveillance system prototype will be developed to incorporate the findings of the research with tools to visualise and describe events.Read moreRead less
Improved decoding of human brain activity using advanced functional magnetic resonance imaging at ultra-high field strength. Using advanced MRI methods at ultra-high field, this project aims to enable the decoding and reconstruction of visual stimuli, as well as imagined ones from small functional units (layers and columns) in the human brain in vivo. This will be made possible by the use of a new functional MRI method, concurrent high temporal and spatial resolution and whole brain coverage as ....Improved decoding of human brain activity using advanced functional magnetic resonance imaging at ultra-high field strength. Using advanced MRI methods at ultra-high field, this project aims to enable the decoding and reconstruction of visual stimuli, as well as imagined ones from small functional units (layers and columns) in the human brain in vivo. This will be made possible by the use of a new functional MRI method, concurrent high temporal and spatial resolution and whole brain coverage as well as high sensitivity and specificity. Additionally, it will advance the development of functional connectomics and the aid the parcellation of the human cortex.Read moreRead less