Achieving Better Mental Health For Maltreated Children: Translating Population Data Into Policy
Funder
National Health and Medical Research Council
Funding Amount
$522,706.00
Summary
This project uses linked population data to determine (a) the earliest indicators of risk of harm, and (b) mental health outcomes and health-care costs associated with children receiving child protection services, in partnership with the NSW department of Family and Community Services. The findings will ensure timely and effective responses to the most vulnerable children to mitigate adverse mental health and other outcomes associated with early life adversity.
Developmental Schizotypy In The General Population: Early Risk Factors And Predictive Utility.
Funder
National Health and Medical Research Council
Funding Amount
$830,952.00
Summary
This study will determine early childhood risk factors for psychosis-proneness in children aged 11 years, and emerging signs and symptoms of mental health disorders of these children, using population data from the NSW Child Development Study. Determining risk for psychosis as early as possible in the life course will enable the provision of preventative interventions to children at critical points in development.
Literary Self-Awareness and Parental Love: Challenging Alterity in Contemporary Medieval Studies. Did medieval women write about themselves as gendered individuals? Did medieval parents love their children? Despite both popular and academic opinion to the contrary, this project aims to demonstrate that these propositions are true. By studying the self-aware writings of Latin-literate medieval women and medieval parent-child advice-texts, this project aims to challenge the alterity, or otherness, ....Literary Self-Awareness and Parental Love: Challenging Alterity in Contemporary Medieval Studies. Did medieval women write about themselves as gendered individuals? Did medieval parents love their children? Despite both popular and academic opinion to the contrary, this project aims to demonstrate that these propositions are true. By studying the self-aware writings of Latin-literate medieval women and medieval parent-child advice-texts, this project aims to challenge the alterity, or otherness, of the Middle Ages, a concept which suggests that medieval people are fundamentally unlike us. In doing so, it questions the significance of alterity in the construction and practices of contemporary Medieval Studies and offers insights into possible new methodologies for the discipline.Read moreRead less
A Population-based Record Linkage Study Of The Impact Of Chlamydia Infection On Reproductive Health In Women
Funder
National Health and Medical Research Council
Funding Amount
$405,114.00
Summary
Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Au ....Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Australia.Read moreRead less
Textual Ontogeny and the Understanding of Modernist Texts: A Case Study of Samuel Beckett's Novel, Watt. This research develops smart technology use: by creating a new method of literary editing that is best able to extend the capabilities of electronic text, this project enhances the understanding of modernist literature and the ability to use technology in innovative ways in the humanities. New ways to organise and edit complex networks of data and documentation (in this case extensive archiva ....Textual Ontogeny and the Understanding of Modernist Texts: A Case Study of Samuel Beckett's Novel, Watt. This research develops smart technology use: by creating a new method of literary editing that is best able to extend the capabilities of electronic text, this project enhances the understanding of modernist literature and the ability to use technology in innovative ways in the humanities. New ways to organise and edit complex networks of data and documentation (in this case extensive archival and published material) will be transferable to a wide variety of non-literary applications.Read moreRead less
The child writer: an edition and critical study of Literary Juvenilia. The project will add significantly to the theorization and documentation of children's literary and cultural history. It will contribute to the establishment of Literary Juvenilia in the academy, making it a viable and recognized area of literary research. It will enlarge and alter the critical reception of childhood writings, in particular those of literary professionals. Such a study will also benefit approaches to liter ....The child writer: an edition and critical study of Literary Juvenilia. The project will add significantly to the theorization and documentation of children's literary and cultural history. It will contribute to the establishment of Literary Juvenilia in the academy, making it a viable and recognized area of literary research. It will enlarge and alter the critical reception of childhood writings, in particular those of literary professionals. Such a study will also benefit approaches to literature in schools (the study of juvenilia can be inspiring for young writers); will show-case Australian authors; and, in ranging across national boundaries,will make an innovative contribution to international relations.Read moreRead less
The Young Writer in History. The project will add significantly to the theorization and documentation of children's literary and cultural history. It will contribute to the establishment of Literary Juvenilia in the academy, making it a viable and recognized area of literary research. It will enlarge and alter the critical reception of childhood writings, particularly in the nineteenth-century. It has the potential to radically alter the boundaries of Children's Literature. Such a study will a ....The Young Writer in History. The project will add significantly to the theorization and documentation of children's literary and cultural history. It will contribute to the establishment of Literary Juvenilia in the academy, making it a viable and recognized area of literary research. It will enlarge and alter the critical reception of childhood writings, particularly in the nineteenth-century. It has the potential to radically alter the boundaries of Children's Literature. Such a study will also benefit approaches to literature in schools (the study of Juvenilia can be inspiring for young writers); and will showcase Australian scholarship that is taking the lead in innovative research in international literary studies.Read moreRead less
Patrick White in the twenty-first century. Patrick White (1912-1990) is the only Australian to be awarded the Nobel Prize for Literature, the citation commending him for having 'introduced a new continent into literature'. How did White represent Australia? Analysis of newly-available manuscripts and related material in the National Library will establish fresh perspectives on White's view of his native land, illuminating his writing in relation to national and international literary traditions. ....Patrick White in the twenty-first century. Patrick White (1912-1990) is the only Australian to be awarded the Nobel Prize for Literature, the citation commending him for having 'introduced a new continent into literature'. How did White represent Australia? Analysis of newly-available manuscripts and related material in the National Library will establish fresh perspectives on White's view of his native land, illuminating his writing in relation to national and international literary traditions. His social and political critique of twentieth-century Australia still confronts readers in the twenty-first century, stimulating debates over such topical issues as national identity, indigeneity, and understanding our national heritage. Read moreRead less
Mechanism Of Action Of Sec1p-like Proteins In Membrane Trafficking
Funder
National Health and Medical Research Council
Funding Amount
$234,936.00
Summary
One of the most important evolutionary changes that has occurred is the development of intracellular compartments. All eukaryotic cells possess numerous membrane-encased structures which provide the basis for intracellular specialisation. For example, in order to degrade unwanted components cells have developed degradative enzymes. It is vital for the cell that these enzymes are sequestered away from other cellular components to avoid destruction of valuable molecules. In addition, the cell has ....One of the most important evolutionary changes that has occurred is the development of intracellular compartments. All eukaryotic cells possess numerous membrane-encased structures which provide the basis for intracellular specialisation. For example, in order to degrade unwanted components cells have developed degradative enzymes. It is vital for the cell that these enzymes are sequestered away from other cellular components to avoid destruction of valuable molecules. In addition, the cell has developed a complex assembly line of modifications that are added to proteins in a specific order as they travel to their final destination within the cell. This necessitates the accurate passage of molecules between compartments, a process known as vesicle transport. To orchestrate the complex network of vesicular transport steps between all of the various intracellular compartments it is necessary to employ complex machinery to guide and check that these steps occur with high fidelity. The goal of our research proposal is to define the function of one of the molecules involved in this control process, the so-called Sec1p proteins. The strength of our proposal lies in the diversity of our approach. We intend to explore the molecular advantages of a relatively simple eukaryotic organism, a yeast cell, and apply the findings obtained from this cell to a more complex but highly related vesicular transport process; that of the insulin-regulated movement of a glucose transporter in mammalian fat and muscle cells. While we intend to apply our findings to the treatment of patients with diabetes, it is our ultimate goal to be able to learn more about this fundamental cell biological process so that we can apply our knowledge to understanding many different disease states.Read moreRead less
Frank Hurley: The Making of a Modern Cultural Icon. I propose to write a book about Frank Hurley (1885-1962) dealing comprehensively for the first time with his photography, cinematography and writing from the perspective of the new humanities disciplines, and to make an original argument about the significance of his career for modern Australian culture in its international contexts. The book will exemplify a new theory and practice of interdisciplinary research. A second objective is to publis ....Frank Hurley: The Making of a Modern Cultural Icon. I propose to write a book about Frank Hurley (1885-1962) dealing comprehensively for the first time with his photography, cinematography and writing from the perspective of the new humanities disciplines, and to make an original argument about the significance of his career for modern Australian culture in its international contexts. The book will exemplify a new theory and practice of interdisciplinary research. A second objective is to publish an edition of Hurley's diaries. Melbourne University Press have formally expressed interest in both books. The text of the diaries will also be made available on the internet by the Mitchell Library and National Library of Australia. Read moreRead less