Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant ....Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant contributions to the new and evolving priority research area of Bioinformation Science (including bioinformatics). Outcomes will include novel techniques for analysis and mining of post-genome data, with applications to developments in Bio-medicine and Bio-agricultureRead moreRead less
New mathematical and statistical methods that inform the control of infectious disease outbreaks. Emerging infectious diseases are an ever-present threat to our community, as highlighted by the recent SARS epidemic and current fears concerning avian influenza. The research proposed by this project will help policy makers implement effective border control and outbreak control against a variety of emerging and re-emerging infectious diseases, including SARS, influenza and the deliberate release o ....New mathematical and statistical methods that inform the control of infectious disease outbreaks. Emerging infectious diseases are an ever-present threat to our community, as highlighted by the recent SARS epidemic and current fears concerning avian influenza. The research proposed by this project will help policy makers implement effective border control and outbreak control against a variety of emerging and re-emerging infectious diseases, including SARS, influenza and the deliberate release of an infectious disease such as smallpox. The project will enhance preparedness through a better understanding of the relative merits of different control strategies, and provide new methodology that can dynamically guide border and outbreak control in the midst of an outbreak by making effective use of data. Read moreRead less