Rapid point-of-care detection of genomic variations for personalised medicine. Selecting treatment based on a person’s genetic profile can improve drug safety and efficacy, but the application is hampered by the inconvenience, slow result turnaround and high cost of current lab-based tests. Full implementation of personalised medicine in clinical practice requires a point-of-care testing system. This project aims to overcome the challenges involved in developing such a system by validating novel ....Rapid point-of-care detection of genomic variations for personalised medicine. Selecting treatment based on a person’s genetic profile can improve drug safety and efficacy, but the application is hampered by the inconvenience, slow result turnaround and high cost of current lab-based tests. Full implementation of personalised medicine in clinical practice requires a point-of-care testing system. This project aims to overcome the challenges involved in developing such a system by validating novel rapid genotyping methods and developing ultrasensitive real-time DNA detection that will be integrated on a single chip platform to facilitate a small, low cost and reliable test device. The technology will be readily adaptable to areas where prompt access to genomic information is valuable, such as disease diagnosis and risk prediction.Read moreRead less
A novel platform-technology for long-term subcutaneous neurophysiology. This project aims to develop a novel miniature device for subcutaneous and tetherless brain sensing. It addresses the lack of a device solution for brain-sensing that combines ultra-long-term reliable sensing capability and small dimensions for minimally-invasive procedures. We achieve this through our novel electrode architecture that significantly enhances the quality and reliability of recorded brain signals. We introduce ....A novel platform-technology for long-term subcutaneous neurophysiology. This project aims to develop a novel miniature device for subcutaneous and tetherless brain sensing. It addresses the lack of a device solution for brain-sensing that combines ultra-long-term reliable sensing capability and small dimensions for minimally-invasive procedures. We achieve this through our novel electrode architecture that significantly enhances the quality and reliability of recorded brain signals. We introduce a platform technology designed for subscalp anatomy with future use in various brain-machine interfacing applications relying on reliable, long-term and easy-to-implant systems. This project's device manufacturing, training, and intellectual property are expected to strengthen Australia's position in bioelectronics.Read moreRead less
Diamond glass: An all-carbon technology for neural networks and biosensing. This project aims to use plasma deposition to synthesise diamond glass with the highest purity and the most diamond-like character so that it meets the strict requirements for emerging device applications. The extreme properties of diamond glass arise from the diamond-like bonding of the majority of its atoms. This amorphous, wide bandgap semiconductor is also the hardest known glass. The maximum diamond-like content pos ....Diamond glass: An all-carbon technology for neural networks and biosensing. This project aims to use plasma deposition to synthesise diamond glass with the highest purity and the most diamond-like character so that it meets the strict requirements for emerging device applications. The extreme properties of diamond glass arise from the diamond-like bonding of the majority of its atoms. This amorphous, wide bandgap semiconductor is also the hardest known glass. The maximum diamond-like content possible in diamond glass coatings is unknown, so determining its ultimate performance is difficult. Expected applications include medical diagnostics, non-volatile memories and programmable chips.Read moreRead less
Higher Order Effects in Miniaturized Piezoelectric Devices. The national benefits of this project are: (a) We will provide opportunities to two postdoctoral researchers to pursue cutting edge research on electromagnetic radiation/scattering and self-heating phenomena in microelectronic devices involving ultrathin lossy electrodes. (b) We will provide industry-oriented research on coating and shielding problems in microelectronic devices to two postgraduate students. (c) We will team up with worl ....Higher Order Effects in Miniaturized Piezoelectric Devices. The national benefits of this project are: (a) We will provide opportunities to two postdoctoral researchers to pursue cutting edge research on electromagnetic radiation/scattering and self-heating phenomena in microelectronic devices involving ultrathin lossy electrodes. (b) We will provide industry-oriented research on coating and shielding problems in microelectronic devices to two postgraduate students. (c) We will team up with world leading industrial partners and transfer high-tech know-how to Australia. (d) The outcomes of our research will position Australia as the prime focal point for the design, modelling and simulation of microacoustic devices.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH170100013
Funder
Australian Research Council
Funding Amount
$2,962,655.00
Summary
ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed device ....ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed devices, analytics and integration platforms. New jobs and improved care will see cost reductions, better use of resources and enhanced mental, physical and social well-being.Read moreRead less
The development and testing of a device to enhance the application of repetitive transcranial magnetic stimulation. This project aims to develop and evaluate a new device designed to substantially enhance the use of transcranial magnetic stimulation, a technology, which is increasingly being applied in the treatment of disorders such as depression, as well as in the study of normal and abnormal brain function.
Acoustics of the Didjeridu. We shall undertake a comprehensive experimental and theoretical study of the acoustics of the didjeridu-lips-vocal tract system. There is very little published technical literature on the dynamic acoustics of this important and uniquely Australian instrument, whose operation is surprisingly complex. A combination of stroboscopic measurements of lip motion, acoustic and vocal tract impedance measurements, MRI imaging of the vocal tract and computer modeling will be use ....Acoustics of the Didjeridu. We shall undertake a comprehensive experimental and theoretical study of the acoustics of the didjeridu-lips-vocal tract system. There is very little published technical literature on the dynamic acoustics of this important and uniquely Australian instrument, whose operation is surprisingly complex. A combination of stroboscopic measurements of lip motion, acoustic and vocal tract impedance measurements, MRI imaging of the vocal tract and computer modeling will be used to synthesize all components of the acoustic system into one quantitative model. The expected outcome will be an understanding of this instrument of unparalleled detail.Read moreRead less
DNA Directed Nanofabrication - A novel, universal, highly parallel bottom-up assembly approach. This proposal aims to provide a nanofabrication method that has the potential to strongly impact every aspect of science - from fundamental research to commercial applications by providing a universal, simple low-cost tool to build nanostructures to order. The basic properties of these structures will be studied prior to their integration into new applications. We will be providing a solution to a b ....DNA Directed Nanofabrication - A novel, universal, highly parallel bottom-up assembly approach. This proposal aims to provide a nanofabrication method that has the potential to strongly impact every aspect of science - from fundamental research to commercial applications by providing a universal, simple low-cost tool to build nanostructures to order. The basic properties of these structures will be studied prior to their integration into new applications. We will be providing a solution to a bottleneck that currently limits the scientific advancement and commercial exploitation of nanotechnology. Our proposal describes a 'Nanoassembly' technique, considered by the ARC as Frontier Technologies for Building and Transforming Australian Industries (ARC priority area 3). Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989615
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Melbourne Platform for Surface Characterisation of Structured Materials. The Australian economy is gradually expanding its manufacturing base through the development of the nanotechnology and biotechnology sectors. This will lead to production of a more diverse range of elaborately transformed goods. A key contributor to these export opportunities will be the nanotechnology sector since at the present time no country has a real nanotechnology based economy and there are many niche markets availa ....Melbourne Platform for Surface Characterisation of Structured Materials. The Australian economy is gradually expanding its manufacturing base through the development of the nanotechnology and biotechnology sectors. This will lead to production of a more diverse range of elaborately transformed goods. A key contributor to these export opportunities will be the nanotechnology sector since at the present time no country has a real nanotechnology based economy and there are many niche markets available for smaller countries such as Australia. This proposal helps to build quality control and characterisation infrastructure that will facilitate prototyping and design of nanoscale devices and sensors for next generation manufacturing.Read moreRead less
Unravelling structure-function relationships in high mobility donor-acceptor co-polymers. This project seeks to understand the high-performance of a new generation of semiconducting plastics. This research will enable the development of low-cost printed electronics such as flexible displays and sensors.