Characterisation Of The Pathways Leading To DNA Demethylation In The Embryo.
Funder
National Health and Medical Research Council
Funding Amount
$634,573.00
Summary
Complex living creatures like humans have specialised cells that co-operate to form important organs like brains and reproductive organs. Specialised cells have specific genes locked on or off. When a sperm fertilises an egg, all the switches of the genes that are locked on or off get reset to neutral so that the fertilised egg can divide and grow into all cell types in the body. We do not know how this resetting happens in the egg. This project seeks to discover the mechanism involved.