Identification of novel biomarkers in tears for prostate cancer diagnosis and prognosis. The purpose of this study is to identify novel biomarkers in the tears of patients with CaP. The use of the several techniques will increase the chance of success and enable us to find more diagnostic markers. If successful, the identified proteins may be used to diagnose and determine the stage of cancer. This will help guide clinicians in choosing the best treatment methods for an individual patient. The m ....Identification of novel biomarkers in tears for prostate cancer diagnosis and prognosis. The purpose of this study is to identify novel biomarkers in the tears of patients with CaP. The use of the several techniques will increase the chance of success and enable us to find more diagnostic markers. If successful, the identified proteins may be used to diagnose and determine the stage of cancer. This will help guide clinicians in choosing the best treatment methods for an individual patient. The markers may also be used to monitor the disease progress and the effects of treatment. The results from this study may improve the prognosis of CaP patients.Read moreRead less
Special Research Initiatives - Grant ID: SR0354892
Funder
Australian Research Council
Funding Amount
$40,000.00
Summary
The Australian Protease Network. Proteases are pivotal enzymes during birth, life, ageing and death of all organisms. Proteases regulate most physiological processes by controlling protein activation, synthesis and turnover and are essential for replication and spread of viruses, bacteria and parasites that cause infectious diseases. Blockbuster drugs and diagnostics already target a few proteases. Australians have made innovative contributions individually to understanding and regulating these ....The Australian Protease Network. Proteases are pivotal enzymes during birth, life, ageing and death of all organisms. Proteases regulate most physiological processes by controlling protein activation, synthesis and turnover and are essential for replication and spread of viruses, bacteria and parasites that cause infectious diseases. Blockbuster drugs and diagnostics already target a few proteases. Australians have made innovative contributions individually to understanding and regulating these enzymes. However this initiative aims to network their efforts by value-adding to the current protease research through promoting national and international collaborations to improve our understanding of biology, and encourage exploitation of proteases/inhibitors/receptors for pharmaceutical and industrial applications.Read moreRead less
Protein And Peptide Alpha Turns. All life is controlled by the structures and functions of proteins. Major components of proteins are alpha helices that are combinations of alpha turns. Different types of alpha turns exist in proteins but have not been well studied. This project will discover and classify alpha turns in proteins, create the first small molecules that contain alpha turns outside of complex protein environments, and provide a better understanding of their chemical, structural and ....Protein And Peptide Alpha Turns. All life is controlled by the structures and functions of proteins. Major components of proteins are alpha helices that are combinations of alpha turns. Different types of alpha turns exist in proteins but have not been well studied. This project will discover and classify alpha turns in proteins, create the first small molecules that contain alpha turns outside of complex protein environments, and provide a better understanding of their chemical, structural and biological properties. Results will teach scientists important details about protein structure and function, train scientists at a frontier of chemistry-biology research, and may contribute to national priorities by triggering new approaches to medicines and novel materials.Read moreRead less