Improved Hygiene Measures For Australian Child Care Centres: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$440,573.00
Summary
Roughly fifty percent of young Australian children receive care outside their home. As greater numbers of women choose to continue working after childbirth, the proportion of children exposed to group care in the first few years of life will continue to increase. In developed countries child care attendance has been shown to be the most important modifiable risk factor for respiratory tract infections and otitis media. A previous study in nine Darwin child care centres demonstrated high rates of ....Roughly fifty percent of young Australian children receive care outside their home. As greater numbers of women choose to continue working after childbirth, the proportion of children exposed to group care in the first few years of life will continue to increase. In developed countries child care attendance has been shown to be the most important modifiable risk factor for respiratory tract infections and otitis media. A previous study in nine Darwin child care centres demonstrated high rates of respiratory tract infections, otitis media, antibiotic use and colonisation with both penicillin-sensitive and penicillin-resistant pneumococci. This study will assess the impact of simple hygiene measures on rates of pneumococcal colonisation, respiratory infection, otitis media, and pneumococcal antibiotic resistance. Twenty child care centres will be randomised to receive additional training and education in the prevention of spread of respiratory infection or routine care. Outcomes measures will include the number of new infection with Streptococcus pneumoniae and Haemophilus influenzae, reported illnesses, and rates of otitis media and nasal discharge documented by fortnightly examination with video recording and tympanometry. Efficacy of the intervention will be estimated at the end of the school year (9 months after the intervention) to avoid bias associated with changes in the child care environment that occur over the school holidays. The centres randomised to routine care will receive the full intervention at the completion of the study and all centres will be re-assessed 6 months .Read moreRead less
Caries Initiation Across Childhood To Adulthood By Exposure To Water Fluoridation
Funder
National Health and Medical Research Council
Funding Amount
$198,297.00
Summary
This research program is expected to contribute to filling significant gaps in the understanding of factors determining the oral health of Australian children and young adults. The purpose of the project is to develop a better understanding of the outcome of long-term exposure to fluoridated water among young adults.
The Receptor-associated Protein (RAP) As A Molecular Chaperone For The Amyloid Protein (Abeta) Of Alzheimers Disease
Funder
National Health and Medical Research Council
Funding Amount
$402,403.00
Summary
Our research will examine the role of a protein known as the receptor-associated protein (RAP) in Alzheimer's disease. We will determine whether the protein contributes to the progression of Alzheimer's disease and we will examine the possiblity that that RAP may be used as a drug to treat the disease. The project could potentially have direct benefit for patients by leading to an effective treatment for dementia associated with Alzheimer's disease.
The South Australian Dental Longitudinal Study has been the first comprehensive dental longitudinal study of older adults to be conducted in Australia. Participants were aged 60+ years at the 1991 baseline data collection, and were a random sample of community-dwelling older adults in urban Adelaide and rural Mount Gambier. The 11-year follow-up data collection will build upon the previous study findings to provide important and new information about the onset and progression of oral diseases in ....The South Australian Dental Longitudinal Study has been the first comprehensive dental longitudinal study of older adults to be conducted in Australia. Participants were aged 60+ years at the 1991 baseline data collection, and were a random sample of community-dwelling older adults in urban Adelaide and rural Mount Gambier. The 11-year follow-up data collection will build upon the previous study findings to provide important and new information about the onset and progression of oral diseases in older Australians. It will also assist with the identification of general health and other characteristics (socio-demographic, medical, functional, cognitive, nutritional, swallowing, dental history, oral hygiene care, financial, social support and oral disorder social impact characteristics) that are associated with oral diseases in various groups of older adults. Groups of older adults within the study include those who are healthy and living in the community, those who are frail and use support services, and those who have moved into residential care. This information will assist both private and public health sectors, dental professionals and other health professionals with the identification of those older adults who are at high risk for developing oral diseases, such as those with dementia, those with physical disabilities, and those living in residential care. This 11-year data collection will be one of only 4 similar international studies currently being conducted, and will provide important comparison data for future studies of older Australians.Read moreRead less
Evaluating The Effectiveness Of Future Tobacco Control Strategies
Funder
National Health and Medical Research Council
Funding Amount
$368,112.00
Summary
This research will evaluate promising new strategies to reduce the harm caused by tobacco, the leading preventable cause of premature death in Australia. This includes evaluation of general population-based strategies, such as public smoking bans, and interventions to help smokers quit smoking, such as new cessation aids and long-term maintenance on pharmaceutical nicotine or low-nitrosamine smokeless tobacco.