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The drowned: cultural and political geographies. This project aims to reveal and critically analyse the geographies of drowning and the drowned. Drowning is the third most common cause of death worldwide, and a subject of universal interest that is relatively limited in specifically cultural and political geographical research, policy, and debate. The project will be significant by rectifying that gap and investigating shared concerns about drowning’s abiding, widespread, profound effects. The e ....The drowned: cultural and political geographies. This project aims to reveal and critically analyse the geographies of drowning and the drowned. Drowning is the third most common cause of death worldwide, and a subject of universal interest that is relatively limited in specifically cultural and political geographical research, policy, and debate. The project will be significant by rectifying that gap and investigating shared concerns about drowning’s abiding, widespread, profound effects. The expected outcomes will include public debate about drowning and its cultural and political reach and management generated from a book, articles, and blog. Benefits will include new fundamental knowledge and practical insights about how to rethink risks and disasters in rapidly changing environments.Read moreRead less
Geographies of house and contents under-insurance. This project aims to analyse house and contents insurance to advance strategic disaster management. When natural disasters strike, house and contents insurance provides a safety net, but many households are under-insured or not insured at all. Governments and communities tend to bear the costs, but the geographies of inadequate insurance, including any crucial post-disaster effects, are unknown. This research is expected to strategically improve ....Geographies of house and contents under-insurance. This project aims to analyse house and contents insurance to advance strategic disaster management. When natural disasters strike, house and contents insurance provides a safety net, but many households are under-insured or not insured at all. Governments and communities tend to bear the costs, but the geographies of inadequate insurance, including any crucial post-disaster effects, are unknown. This research is expected to strategically improve disaster policy and practice, and reduce the financial and social costs of disasters to governments, communities and householders.Read moreRead less
Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge mic ....Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge microscopy techniques to visualise whether the endogenous astrocyte protein metallothionein can promote regeneration in the injured nervous system of living zebrafish. The successful outcomes of this project will provide significant insight into understanding how the brain responds to injury.Read moreRead less
Caring for thoroughbreds: addressing social, economic and welfare issues in international horse racing. Horse racing is an economically valuable industry but visible welfare issues are challenging its future. This study addresses perceptions and the economic worth of these issues internationally. Research findings about values, and alternatives to jump racing and whipping horses, will help change the conduct of horse racing around the world.
A Game Changer? Alcohol and Women's Sport in Australia. This project aims to investigate emerging relationships between women and alcohol in Australian sport. We will examine the meanings that drinking may have for sportswomen and female fans, and identify new theoretical frameworks for rethinking drinking, gender and sport. In the context of public and policy debates about the risks and social impacts of alcohol consumption, we expect to generate significant new knowledge outcomes. These includ ....A Game Changer? Alcohol and Women's Sport in Australia. This project aims to investigate emerging relationships between women and alcohol in Australian sport. We will examine the meanings that drinking may have for sportswomen and female fans, and identify new theoretical frameworks for rethinking drinking, gender and sport. In the context of public and policy debates about the risks and social impacts of alcohol consumption, we expect to generate significant new knowledge outcomes. These include a world first research corpus of direct relevance for sports administrators and policy-makers, who are currently grappling with the costs and consequences of alcohol use in licensing and legislation, as well as in marketing, sponsorship and promotion of sport to women.Read moreRead less
Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-th ....Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-thalassaemia, understanding the specific aHb-binding factor, AHSP is a goal of national significance. In the long term, manipulation of AHSP function through gene therapy may have a direct role in the treatment of thalassaemia.Read moreRead less
Vulnerability, autonomy and justice. Vulnerable people require assistance and care. But what are our responsibilities in relation to the vulnerable? And how can we provide assistance and care while avoiding stereotyping or paternalism? This research will advance ethical theory and be useful in solving practical problems in health research and policy.
Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These a ....Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These are significant community issues in both economical and social terms. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest cellular processes associated with aging or disease of the brain, and will provide clues to promoting healthy aging.Read moreRead less
Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to th ....Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or neurodegenerative disease. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest biochemical and cellular processes associated with aging or disease of the brain.Read moreRead less
The Inception of Criminal Deportation in Colonial Australia . This project aims to undertake the first comprehensive study of criminal deportation in colonial Australia. Expected outcomes include new knowledge on freely arrived colonists who were tried, sentenced to transportation, and criminally deported within the Australian colonies. The project spans the disciplines of history and criminology, developing a new methodological framework that aims to facilitate important insights on the societa ....The Inception of Criminal Deportation in Colonial Australia . This project aims to undertake the first comprehensive study of criminal deportation in colonial Australia. Expected outcomes include new knowledge on freely arrived colonists who were tried, sentenced to transportation, and criminally deported within the Australian colonies. The project spans the disciplines of history and criminology, developing a new methodological framework that aims to facilitate important insights on the societal attitudes, systems, and circumstances that led to criminal deportation. This should provide significant benefits by articulating the unexplored deep history of Australian criminal deportation practices. The project also aims to preserve fragile colonial documents foundational to the nation’s history.Read moreRead less