Reducing wear on rotary coal pulverisers. The aim of this project is to develop an understanding of the small-scale flows and particle breakage required to permit optimised redesign of the attrition stage of the 36 coal pulverisers at Gladstone Power Station, which, because of erosive wear, currently have a maintenance budget of $4M per year. CFD-DEM simulation of the air and particle flows will be used to determine particle flow patterns, particle-particle and particle-wall impact energies. Thi ....Reducing wear on rotary coal pulverisers. The aim of this project is to develop an understanding of the small-scale flows and particle breakage required to permit optimised redesign of the attrition stage of the 36 coal pulverisers at Gladstone Power Station, which, because of erosive wear, currently have a maintenance budget of $4M per year. CFD-DEM simulation of the air and particle flows will be used to determine particle flow patterns, particle-particle and particle-wall impact energies. This information will be input to comminution and wear models to predict pulveriser performance and wear patterns. Simulation results will be validated using measurements from scale visualisation and working models.Read moreRead less
Environmentally Sustainable Solvents for Natural Pharmaceutical Extraction Processes. Australia supplies 25 per cent of the world's pain relieving medicinal opiates which contributes to a $200 million export industry for Australia. The active pharmaceutical ingredients are extracted and purified at GlaxoSmithKline’s (GSK) Port Fairy processing plant using a solvent extraction based process. Together with GSK the project team aim to examine the use of environmentally sustainable bio-derived natur ....Environmentally Sustainable Solvents for Natural Pharmaceutical Extraction Processes. Australia supplies 25 per cent of the world's pain relieving medicinal opiates which contributes to a $200 million export industry for Australia. The active pharmaceutical ingredients are extracted and purified at GlaxoSmithKline’s (GSK) Port Fairy processing plant using a solvent extraction based process. Together with GSK the project team aim to examine the use of environmentally sustainable bio-derived natural solvents to replace the volatile organic compound (VOC) fossil fuels based solvents used in the current process. Due to environmental and health concerns associated with VOCs the development of alternative solvents will be of great benefit to not only GSK but a range of other processing industries that also use VOC based solvent extraction processes.Read moreRead less
Immune-imprinting nanoparticles (iNPs). This research promises new classes of immune-imprinting, biodegradable nanoparticles (iNPs) with anti-inflammatory properties. The engineering of such particles requires fundamental understanding of their properties that enable specific cellular interactions to regulate immunity with new anti-inflammatory pathways. For pulmonary delivery, spray-dried amino acid microspheres with tailored surfaces as carriers can be generated using the innovative microfluid ....Immune-imprinting nanoparticles (iNPs). This research promises new classes of immune-imprinting, biodegradable nanoparticles (iNPs) with anti-inflammatory properties. The engineering of such particles requires fundamental understanding of their properties that enable specific cellular interactions to regulate immunity with new anti-inflammatory pathways. For pulmonary delivery, spray-dried amino acid microspheres with tailored surfaces as carriers can be generated using the innovative microfluidic drying approach. The potential applications of iNPs are wide-ranging and are not restricted to pulmonary targeting. The potential commercial implications for Australia's emerging biopharmaceutical industry are substantial.Read moreRead less
Advanced environmental technologies for increasing coal seam permeability. This project aims to understand the physical/chemical mechanisms occurring when benign chemicals interact and dissolve minerals and coal surfaces in the natural fractures during the extraction of coal seam gas. Technologies for increasing the permeability of coal have become necessary for commercially viable coal seam gas (CSG) extraction in Australia. Currently available methods from the conventional gas industry, are pr ....Advanced environmental technologies for increasing coal seam permeability. This project aims to understand the physical/chemical mechanisms occurring when benign chemicals interact and dissolve minerals and coal surfaces in the natural fractures during the extraction of coal seam gas. Technologies for increasing the permeability of coal have become necessary for commercially viable coal seam gas (CSG) extraction in Australia. Currently available methods from the conventional gas industry, are problematic for coal, and fail to capitalise on coal’s existing fracture network. The intended project outcome is a range of new coal-specific technologies for enhancing permeability that avoid unwanted and irreversible damage to seams and protect the environment. Combined with reduced costs, these methods would benefit sustainable growth of Australia’s CSG industry.Read moreRead less
The Development of New Carrier Technologies for Spray-Dried Fruit Extracts. This project aims to develop new carrier techniques for spray drying fruit extracts based on the use of natural fibres, with the aim of overcoming a key problem in the operation of spray dryers for producing powders, the deposition of particles on walls. Carriers are non-sticky materials that effectively dilute the stickiness of any materials. The significance is that it will use waste products from fruit processing (th ....The Development of New Carrier Technologies for Spray-Dried Fruit Extracts. This project aims to develop new carrier techniques for spray drying fruit extracts based on the use of natural fibres, with the aim of overcoming a key problem in the operation of spray dryers for producing powders, the deposition of particles on walls. Carriers are non-sticky materials that effectively dilute the stickiness of any materials. The significance is that it will use waste products from fruit processing (the fibres from skins) to overcome this problem, and it will also be possible to dry sticky materials using material from the fruit itself, rather than additives such as maltodextrin.Read moreRead less
A skin-on-a-chip device for investigating wound healing. This project aims to research the mechanism of skin wound healing. It will design a skin-on-a-chip microfluidic device that mimics human skin in vitro. This device will reduce the need for animal studies and assess how active compounds heal wounds. This project will design smart polymers with superior properties for controlled delivery of multiple active compounds in this device and choose the most effective combination of compounds to boo ....A skin-on-a-chip device for investigating wound healing. This project aims to research the mechanism of skin wound healing. It will design a skin-on-a-chip microfluidic device that mimics human skin in vitro. This device will reduce the need for animal studies and assess how active compounds heal wounds. This project will design smart polymers with superior properties for controlled delivery of multiple active compounds in this device and choose the most effective combination of compounds to boost skin healing rate. This knowledge may ultimately be used to develop wound dressings that maximise healing rate for various skin defects such as chronic wounds and decrease health care costs.Read moreRead less
Powder blending for dry powder inhalers: a new approach for direct control of powder structure. Over 80 per cent of pharmaceutical products involve the processing of powders. This project will generate new knowledge of how to assemble fine and cohesive particles into the structure required for dry powder inhaler products, leading to the development of new low-cost medicines in Australia and the Asia Pacific region.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989675
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Interface-specific facility for quantifying adsorption and structures at particulate interfaces. The facility will be used by the collaborating universities to investigate adsorption and interface properties with great precision, and to develop new and improved technologies for coal and mineral processing, saline water utilisation, water desalination, energy production and environment protection. In particular, the project will investigate innovative ways of using ion-interface interactions in ....Interface-specific facility for quantifying adsorption and structures at particulate interfaces. The facility will be used by the collaborating universities to investigate adsorption and interface properties with great precision, and to develop new and improved technologies for coal and mineral processing, saline water utilisation, water desalination, energy production and environment protection. In particular, the project will investigate innovative ways of using ion-interface interactions in saline water for cleaning coal and recovering value minerals by flotation, and for improving dissolved air flotation used in water treatment and desalination to produce drinking water. The project will further investigate novel ways of capturing CO2, storing natural gases and hydrogen, and tailoring nutrient nano-crystals for foliar delivery.Read moreRead less
Combating the spread of antibiotic resistance in urban water systems. This projects aims to investigate the occurrence, diversity, and transformation of antibiotic resistant genes in the entire urban water cycle. Using the latest metagenomic and analytical tools, this project will enhance our knowledge on fate and transfer mechanisms of antibiotic resistance genes in the urban water cycle. Based on this understanding, an expected outcome of the project is the development of innovative technologi ....Combating the spread of antibiotic resistance in urban water systems. This projects aims to investigate the occurrence, diversity, and transformation of antibiotic resistant genes in the entire urban water cycle. Using the latest metagenomic and analytical tools, this project will enhance our knowledge on fate and transfer mechanisms of antibiotic resistance genes in the urban water cycle. Based on this understanding, an expected outcome of the project is the development of innovative technologies for efficient reduction of antibiotic resistance genes to have future applications for environmental, human health and economic benefits for Australia.Read moreRead less
Model studies of Australian lump ore applied to blast furnace ironmaking. Ore lump use in ironmaking blast furnaces (BFs) requires no preprocessing and has a lower carbon footprint. However, it suffers various technical problems. This project aims to understand and optimize the conditions for such operations. This will be achieved by means of a combined theoretical and experimental program, involving the use of state-of-the-art multiscale computer modelling and simulation techniques. The researc ....Model studies of Australian lump ore applied to blast furnace ironmaking. Ore lump use in ironmaking blast furnaces (BFs) requires no preprocessing and has a lower carbon footprint. However, it suffers various technical problems. This project aims to understand and optimize the conditions for such operations. This will be achieved by means of a combined theoretical and experimental program, involving the use of state-of-the-art multiscale computer modelling and simulation techniques. The research outcomes will be tested in the design and control of lump charging operations in practice through collaboration with the industrial partner. This will ultimately increase Australian ore lump usage in BFs, leading to significant financial and environmental benefits to Australia and the entire steel industry worldwide.Read moreRead less