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Human Neural Development In The Absence Of Species-expected Stimuli: The Effect Of Maternal Or Social Deprivation On Maturation Of Emotion Circuitry During Critical Periods Of Development.
Funder
National Health and Medical Research Council
Funding Amount
$465,103.00
Summary
As children mature into adolescents, social influences on emotional responding transition from parents to peers. Understanding how social stimuli shape neural circuits that ultimately regulate emotional behaviour will yield critical information for treatment and prevention of emotional disorders across the lifespan. The current project addresses this important issue through the use of functional imaging of emotion circuits in the brain and classical conditioning approaches to emotion responding.
Identification Of Genes Responsible For Disorders Of Sexual Development Using Genome-wide Copy Number Analysis
Funder
National Health and Medical Research Council
Funding Amount
$305,774.00
Summary
Congenital conditions in which development of the gonads or anatomical sex is abnormal are surprisingly common. The underlying cause of these problems is most often the failure of genes responsible for the proper development of testes or ovaries. Only a small proportion of patients can be explained by mutations in known gonad determining genes. We will analyse DNA from these patients on very high density microarrays to identify new genes that cause abnormalities in testis or ovary development.
Investigating A Theoretical Model Of Cognitive Control In Children With Attention Deficit Hyperactivity Disorder (ADHD): Informing Our Approach To Cognitive Training.
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
ADHD is the most common childhood developmental disorder, characterised by inattentive and/or hyperactive behaviours. Cognitive control has been highlighted as a potential mediator of ADHD symptoms. This program will i) delineate the relationship between cognitive control and ADHD symptoms, ii) develop a cognitive training intervention to target the underlying mechanisms identified as mediators of ADHD symptoms and iii) evaluate the program in a gold-standard clinical trial.