Innovative Health Programs To Reduce Inequality In Heart Disease
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
As part of his Senior NHMRC Fellowship, Prof Simon Stewart, a world-renowned health services researcher, will lead an internationally linked team of researchers from a broad range of health disciplines to undertake a program of research designed to improve the lives of those most vulnerable to heart disease and poor health outcomes. His program of research will focus on Indigenous Australians, patients with complex forms of heart disease and urban African communities in economic transition.
Evaluating The Genetic Contribution To Rheumatic Heart Disease Pathogenesis In Australian Aboriginal And Torres Strait Islander Communities
Funder
National Health and Medical Research Council
Funding Amount
$1,782,074.00
Summary
Rheumatic heart disease is highly prevalent in Aboriginal people in Australia and leads to early cardiac disease. Despite decades of research, the underlying genetic mechanisms for why it occurs are not well understood. We are conducting a genetic study to better understand why some people are susceptible to RHD and others are not. The study will involve substantial Aboriginal leadership and consultation and will be a model for the conduct of genetic studies in Aboriginal populations.
Can Skin Infection With Group A Streptococcus Cause Acute Rheumatic Fever?
Funder
National Health and Medical Research Council
Funding Amount
$459,450.00
Summary
It is traditionally taught that the cause of acute rheumatic fever (ARF) is always infection of the throat with the bacterium group A streptococcus (GAS). However, in Aboriginal communities of the Top End of the Northern Territory the incidence of ARF is the highest reported in the world, yet GAS is uncommonly isolated from the throat. There is further information to suggest that GAS skin sores may underlie many cases of ARF. If this were proven, it would completely alter the traditional view of ....It is traditionally taught that the cause of acute rheumatic fever (ARF) is always infection of the throat with the bacterium group A streptococcus (GAS). However, in Aboriginal communities of the Top End of the Northern Territory the incidence of ARF is the highest reported in the world, yet GAS is uncommonly isolated from the throat. There is further information to suggest that GAS skin sores may underlie many cases of ARF. If this were proven, it would completely alter the traditional view of the cause of ARF, and have important implications for prevention of ARF around the world. Presently, these approaches focus on diagnosing and treating sore throat, but no country has proven that such a program can be successful in substantially reducing new cases of ARF. If it was known that skin infection could lead to ARF, then countries (including Australia) could emphasise the importance of skin health programs. A further benefit of this knowledge would be to influence GAS vaccine development, which presently is largely focused on the prevention of sore throat. A different possibility has recently been raised - that the cause of ARF may not always be GAS, but instead that the related bacteria GCS and GGS may have the potential to cause this disease. Proof of this hypothesis would even more dramatically alter our understanding of disease causation, prevention, and vaccine development. We propose to determine the cause of ARF in Aboriginal communities by regularly swabbing families of people with a history of ARF, and using genetic fingerprinting of the bacteria from the skin and throat swabs. When cases of ARF occur, we will be able to determine the site and type of infection that precipitated the attack. We will conduct a related study in more communities, in which we will swab family members of people with ARF and of control families (without ARF) to determine the bacteria most commonly isolated from ARF families.Read moreRead less
CENTRE OF RESEARCH EXCELLENCE TO REDUCE INEQUALITY IN HEART DISEASE
Funder
National Health and Medical Research Council
Funding Amount
$2,607,253.00
Summary
There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health ....There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health care services.Read moreRead less
A National Population-based Study Of Rheumatic Heart Disease In Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$877,826.00
Summary
Whilst overall a rare disease, Indigenous peoples have disproportionately high rates of rheumatic heart disease (RHD). This study explores the prevalence and distribution of RHD in pregnancy in Australia and New Zealand. It details current management, diagnostic and referral process and risk factors. Key attributes of culturally safe models of care for RHD in pregnancy are explored, particularly as they relate to Indigenous women. Findings will inform policy, guidelines and education resources.
The invisible parents project - exploring the barriers to effective parental and community involvement in three Northern Territory Schools. Education outcomes in the Northern Territory, particularly for Indigenous students, lag far behind those of other Australians, to the point that the situation can be considered a national emergency. This research program will explore ways to improve parental involvement. This will inform the Smith Family's efforts to undertake early intervention for children ....The invisible parents project - exploring the barriers to effective parental and community involvement in three Northern Territory Schools. Education outcomes in the Northern Territory, particularly for Indigenous students, lag far behind those of other Australians, to the point that the situation can be considered a national emergency. This research program will explore ways to improve parental involvement. This will inform the Smith Family's efforts to undertake early intervention for children who are at risk of education failure. It will provide benefits to the rural and regional communities who feed schools in Darwin and Katherine and provide national benefits through making a significant contribution of anthropologically-informed knowledge on the determinants of successful school outcomes.Read moreRead less
Playing for Life: A Case Study in Childhood, Culture and Transition. This study will advance Australian research on identity formation in postcolonial societies; develop child-focused research in academic anthropology; align Australian Aboriginal Studies with recent international progress in the field of children's social imagination; innovate the analysis of transforming Indigenous worldviews; create a perspective for in-depth psychological research with Aboriginal Australians; build a rich res ....Playing for Life: A Case Study in Childhood, Culture and Transition. This study will advance Australian research on identity formation in postcolonial societies; develop child-focused research in academic anthropology; align Australian Aboriginal Studies with recent international progress in the field of children's social imagination; innovate the analysis of transforming Indigenous worldviews; create a perspective for in-depth psychological research with Aboriginal Australians; build a rich resource for comparative research and for teaching. It also offers distinct social benefits: fostering the understanding of Aboriginal children's social and mental needs in processes of cultural transformation; enhancing equality by identifying the positive potentials in children and Aboriginal society.
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Determining implementation drivers in resilience education. Determining implementation drivers in resilience education. This project aims to develop implementation frameworks to help the education sector universally provide resilience education programmes. More young people have mental health problems. Although evidence-based resilience education reduces these problems, education sectors do not know how to address barriers to school provision. The solution is implementation research. This projec ....Determining implementation drivers in resilience education. Determining implementation drivers in resilience education. This project aims to develop implementation frameworks to help the education sector universally provide resilience education programmes. More young people have mental health problems. Although evidence-based resilience education reduces these problems, education sectors do not know how to address barriers to school provision. The solution is implementation research. This project will study system and school-level factors influencing primary and high school uptake of social and emotional learning curricula that enhance resilience; and implementation drivers at both system and school levels, and influences on uptake and student and staff resilience. The outcome is universal provision of resilience education programs that benefit young people.Read moreRead less
Incentivising On Country Aboriginal Employment: Anangu Futures. . This project aims to investigate the changing face of cultural tourism in central Australia and examine pathways towards sustainable aboriginal employment in and around Uluru-Kata Tjuta National Park. The project is significant because it brings together Aboriginal community members, industry and government stakeholders to identify micro-business opportunities, youth training initiatives, better relations across cultural divides, ....Incentivising On Country Aboriginal Employment: Anangu Futures. . This project aims to investigate the changing face of cultural tourism in central Australia and examine pathways towards sustainable aboriginal employment in and around Uluru-Kata Tjuta National Park. The project is significant because it brings together Aboriginal community members, industry and government stakeholders to identify micro-business opportunities, youth training initiatives, better relations across cultural divides, and the economic value of Aboriginal knowledge. Outcomes include a model for sustainable Aboriginal employment in remote and very remote contexts, and the development of culturally relevant and sustainable governing guidelines for regional investment. Benefits include more sustainable jobs for Aboriginal people.Read moreRead less
Securing the essential: assisting Indigenous communities and their service providers to sustainably manage water and energy supply. The provision of water and energy supplies to remote Aboriginal and Torres Strait Islander (ATSI) communities is a critical challenge for service providers. This project uses a novel unobtrusive smart metering system, aligned with culturally appropriate consultation with ATSI communities, to reveal patterns of household water and water related-energy consumption. Si ....Securing the essential: assisting Indigenous communities and their service providers to sustainably manage water and energy supply. The provision of water and energy supplies to remote Aboriginal and Torres Strait Islander (ATSI) communities is a critical challenge for service providers. This project uses a novel unobtrusive smart metering system, aligned with culturally appropriate consultation with ATSI communities, to reveal patterns of household water and water related-energy consumption. Significantly, the research aims to identify effective behavioural and technological water and energy efficiency strategies in three remote ATSI communities in Queensland, Northern Territory and Western Australia. A key outcome is to provide an adaptive evidence-based and community-driven handbook to facilitate the secure long-term supply and efficient use of energy and water resources in remote ATSI communities.Read moreRead less