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Suction pipette measurements of mammalian rod photoreceptor recovery following intense bleaching exposures. The aim of this project is to discover the events and processes that prevent retinal photoreceptors from recovering instantaneously following the cessation of exposure to extremely bright illumination. Recordings will be made from single rod photoreceptors cells isolated from the mammalian retina. The work will uncover the relative roles of the 'photoproducts' created when rhodopsin abso ....Suction pipette measurements of mammalian rod photoreceptor recovery following intense bleaching exposures. The aim of this project is to discover the events and processes that prevent retinal photoreceptors from recovering instantaneously following the cessation of exposure to extremely bright illumination. Recordings will be made from single rod photoreceptors cells isolated from the mammalian retina. The work will uncover the relative roles of the 'photoproducts' created when rhodopsin absorbs light: e.g. intermediates such as metarhodopsin and opsin. The molecular knowledge obtained will help us to understand why it is that the visual system recovers so slowly after the eye has experienced very intense light.Read moreRead less
The first stage of vision: transduction and adaptation in retinal photoreceptors. The project aims to provide a detailed understanding of the molecular steps involved in the first stage of vision - the conversion of light into a neural signal in the rod and cone photoreceptors of the retina. The significance of this is that it will explain the initial events that enable us to see, and will help explain the deficits that occur when the process fails. The outcome will be a comprehensive understand ....The first stage of vision: transduction and adaptation in retinal photoreceptors. The project aims to provide a detailed understanding of the molecular steps involved in the first stage of vision - the conversion of light into a neural signal in the rod and cone photoreceptors of the retina. The significance of this is that it will explain the initial events that enable us to see, and will help explain the deficits that occur when the process fails. The outcome will be a comprehensive understanding of how our photoreceptors respond with extreme sensitivity, yet great rapidity, and over an enormous range of light intensities, thus endowing us with our remarkable sense of vision.Read moreRead less
Complex Motion Processing in Primate Visual Cortex. As we move through the world, a dynamic visual image is projected onto our retinas. The pattern of movement in the retinal image contains information about three-dimensional structure in the environment and the time of impending collisions. Our visual systems are expert at exploiting this information, enabling us to navigate through complex visual environments at a level far beyond the most sophisticated artificial systems. We plan to investiga ....Complex Motion Processing in Primate Visual Cortex. As we move through the world, a dynamic visual image is projected onto our retinas. The pattern of movement in the retinal image contains information about three-dimensional structure in the environment and the time of impending collisions. Our visual systems are expert at exploiting this information, enabling us to navigate through complex visual environments at a level far beyond the most sophisticated artificial systems. We plan to investigate complex motion processing in the primate brain by recording the responses of neurons in identified regions of the visual cortex of macaque monkeys to a range of behaviourally relevant motion stimuli.Read moreRead less
ARC Research Network for Enabling Human Communication. The Human Communication Network promotes interdisciplinary research in speech, language, and sound by and between humans and machines. The network connects leading and emerging researchers across disciplines, exploits previously unrecognised intersections, supports interdisciplinary graduate training and exchanges, provides database storage infrastructure, and consults with industry and government to set, not follow, research agendas. By ge ....ARC Research Network for Enabling Human Communication. The Human Communication Network promotes interdisciplinary research in speech, language, and sound by and between humans and machines. The network connects leading and emerging researchers across disciplines, exploits previously unrecognised intersections, supports interdisciplinary graduate training and exchanges, provides database storage infrastructure, and consults with industry and government to set, not follow, research agendas. By generating an explosion of new approaches and knowledge, the network will build Australia's reputation as a leader in communication science and technology via advances in automatic speech recognition, distress call monitoring, hearing prostheses, web interfaces, and data retrieval and data mining systems.Read moreRead less
ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision system ....ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision systems with applications in industry and national security. Other knowledge will develop novel diagnostic technologies, for application in health delivery.Read moreRead less
Two-way Auslan: Automatic Machine Translation of Australian Sign Language. This project aims to develop an automatic two-way machine-translation system between Auslan (Australian Sign Language) and English by researching and leveraging advanced computer vision and machine learning technology. The project expects to advance research in AI technology on topics including visual recognition, language processing and deep learning. This will boost Australia's national research capacity and global com ....Two-way Auslan: Automatic Machine Translation of Australian Sign Language. This project aims to develop an automatic two-way machine-translation system between Auslan (Australian Sign Language) and English by researching and leveraging advanced computer vision and machine learning technology. The project expects to advance research in AI technology on topics including visual recognition, language processing and deep learning. This will boost Australia's national research capacity and global competitiveness. Expected outcomes of this project will help to break the communication barriers between the Deaf and hearing population. This should provide significant benefits to Deaf communities through enhanced communication and improved quality-of-life, leading to a fair, more inclusive and resilient Australian society.Read moreRead less
Using Health Outcome Data From Pooled Longitudinal Studies Of Ageing To Develop Statistical And Microsimulation Models T
Funder
National Health and Medical Research Council
Funding Amount
$2,162,630.00
Summary
This project draws together data from nine Australian Longitudinal Studies of Ageing (LSAs), including 53484 participants, that will be used to identify factors capable of preventing disease, reducing ill-health, and promoting engaged and successful ageing for Australians. The focus is upon conditions that significantly contribute to the burden of disease including cognitive decline and dementia, sensory impairment, impairment in mobility and common mental disorders such as depression. Although ....This project draws together data from nine Australian Longitudinal Studies of Ageing (LSAs), including 53484 participants, that will be used to identify factors capable of preventing disease, reducing ill-health, and promoting engaged and successful ageing for Australians. The focus is upon conditions that significantly contribute to the burden of disease including cognitive decline and dementia, sensory impairment, impairment in mobility and common mental disorders such as depression. Although individual studies contain rich data on particular topics, there is only a small number of individuals in each study with specific medical conditions, or combinations of different conditions, especially at the older ages. Pooling data from nine studies will overcome this problem. This innovative and interdisciplinary study also involves development of the first Australian dynamic micro-simulation model of the health and social outcomes of the baby boomer and older cohorts. The simulation will allow for evaluation of the impact of modifying risk factors, and costs associated with different trajectories of health and ageing. Our program takes an interdisciplinary life course approach, incorporating interdependencies among demographic, behavioural, social, economic and health factors. Our multidisciplinary team and collaborative pooling of existing studies adds value and builds upon experience, as recommended in the Prime Minister's Science, Engineering and Innovation Council 2003 report. The outcomes will direct health and social policy to promote health behaviour, and social and medical interventions to compress morbidity and optimize healthy ageing in Australian society over the next 40 years.Read moreRead less
Innovations in Clinical Education for Physiotherapy Students. Australia has workforce shortages and an ageing population. Physiotherapists are key players in promoting and maintaining good health through their leadership in physical activity and rehabilitation to retain Australians in the workforce and to ensure quality of life for our ageing population. There is a national shortage of physiotherapists. Increasing numbers of physiotherapists are being trained, requiring new models of clinical tr ....Innovations in Clinical Education for Physiotherapy Students. Australia has workforce shortages and an ageing population. Physiotherapists are key players in promoting and maintaining good health through their leadership in physical activity and rehabilitation to retain Australians in the workforce and to ensure quality of life for our ageing population. There is a national shortage of physiotherapists. Increasing numbers of physiotherapists are being trained, requiring new models of clinical training as there is no capacity in conventional training to cope with student numbers. This research will develop and evaluate new models of training incorporating standardised patients (actors) and simulators (mannequins) which increase education capacity. Models are transferable to other health professions.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100211
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and developmen ....The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and development using Australian English and facilitate the development of Australian speech technology applications from automatic speech recognition and text-to-speech synthesis used in taxi and other ordering services, to hearing prostheses and talking head aids for learning-impaired children, and a range of security and forensic applications.Read moreRead less