Advancing Health Economic Evaluation Measurement And Design To Support Priority Setting For Vulnerable Children
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
I bring well developed and unique research skills in child health economics, which is concerned with making sure the health system runs fairly and without waste. This research will make significant advancements in economic evaluation methods to ensure we can fairly evaluate health interventions for children. It will assess equity in how health care is funded for children and provide new information to support a fairer health system for children.
Addressing Evidence Gaps And Developing A Novel Treatment To Reduce The Burden Of Post-traumatic Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Arthritis caused by knee injury has a devastating personal and economic impact. Research is needed to develop strategies to prevent arthritis and improve outcomes for people living with arthritis. This research will improve treatment of knee injury to reduce arthritis risk, understand why some people are more likely to get knee arthritis, and develop a new treatment to improve outcomes for people living with knee arthritis. A clinical trial will determine if this treatment achieves this aim.
A Network Approach To Mapping And Modifying Brain Changes In Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$2,163,245.00
Summary
Psychosis fundamentally alters a person’s relationship with reality. Brain scans can map which parts of the brain are affected by psychosis, but they cannot reveal the actual disease processes that cause these changes. I will address this gap by integrating brain imaging with genetics and mathematical modelling to identify the brain circuits and molecules that impact risk for psychosis, and to develop targeted therapies that modify risk-related brain dysfunction.
Generating Evidence For A Strong Foundation: Using Population Health Data For Translational Child Health, Healthcare And Policy
Funder
National Health and Medical Research Council
Funding Amount
$1,500,000.00
Summary
Professor Natasha Nassar’s research program uses advanced research methods to address new challenges in child population health. She will investigate the role and impact of early life factors, paediatric healthcare practices and long-term morbidity and survivorship on child health and development. Identification of at-risk children and involvement of clinicians and policy-makers in research will ensure improved child population health and development and healthy start to life for all children.
Improving Cardiovascular Outcomes Through Better Trials
Funder
National Health and Medical Research Council
Funding Amount
$1,714,215.00
Summary
Randomised trials are the cornerstone of high quality medical practice. There is an urgent need to do more trials but there are major challenges - timely recruitment of participants, inclusion of representative patients and control of costs are issues we face every day. I will commence a series of new trials evaluating interventions for cardiovascular disease. In parallel I will develop and test innovative solutions to the practicalities of doing large-scale studies.
Improved Early Respiratory Support Of Infants And Children
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Worldwide respiratory disease in children has the highest health care burden on society. Children aged <5 years in particular, are increasing in hospital admissions and to intensive care where the cost is elevated. New ways of oxygen therapy have been studied and shown that we can reduce ICU admission if a therapy known as Nasal High Flow (NHF) therapy is applied earlier in the progression of the disease. Further research is needed in NHF therapy and to improve upon our patient outcomes.
Quantifying And Reducing The Burden Of New And Emerging Psychoactive Substances In Australia
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
The public health threat posed by emerging drugs of concern (e.g., new psychoactive substances (NPS) and crystalline methamphetamine) requires timely and effective public health interventions. This research program will strengthen estimates of the global NPS health burden, enhance the surveillance of unwitting drug consumption, and develop and evaluate novel harm reduction responses. Findings will inform policy and health service delivery, both globally and within Australia.
Optimising Engagement In Cardiac Secondary Prevention: A Health Literacy Approach
Funder
National Health and Medical Research Council
Funding Amount
$1,562,250.00
Summary
Many people struggle to maintain a healthy lifestyle after a heart attack. Health literacy is the ability to understand and use health information for better health, but little is known about its role in long-term behaviour change. This research will follow 408 people over 2 years to identify whether health literacy impacts upon lifestyle change after a heart attack. The study will also co-design interventions with consumers and clinicians that aim to improve people’s health literacy.
Improving Reproductive Health Through Infectious Diseases Research
Funder
National Health and Medical Research Council
Funding Amount
$1,957,108.00
Summary
Infectious diseases that impact upon reproductive health remain a major problem worldwide. This proposal will examine human papillomavirus infection, the role of the human microbiota in a number of conditions (necrotising enterocolitis, bacterial vaginosis, and human papillomavirus infection), and antibiotic resistance in sexually transmitted infections. The knowledge generated will be used to improve diagnostics.
Tackling Antimicrobial Resistance In Neonatal Sepsis: Australia And Beyond
Funder
National Health and Medical Research Council
Funding Amount
$566,164.00
Summary
This project aims to establish clear data regarding the burden of antibiotic resistance in neonates in Australia & in our local South East Asian region. This will be achieved by establishing systematic data collection for infections with multi-resistant bacteria in Australian neonatal intensive care units, reviewing published literature regarding the cause of infections in South East Asian neonates, and continuing collaborative work to establish a new treatment regimen for neonatal sepsis.