The Healthy Brain Project: A Prospective Cohort Study To Examine How Later-life University Education May Affect The Trajectory Of Ageing-related Cognitive Decline
Funder
National Health and Medical Research Council
Funding Amount
$1,085,742.00
Summary
Previous research has indicated that higher levels of education in early adulthood are associated with lower risk for dementia in older adults. This world-first project will examine if older adults who undertake university education have reduced rates of age-related cognitive decline than older adults who do not undertake further education. This would support the notion that boosting cognitive reserve in later life is protective against age- and disease-related neurodegenerative change.
Improved electrophoretic analyser for water quality monitoring. This proposal will advance the Australian made Eco Detection portable electrophoretic analyser for autonomous monitoring of water chemistry - the Eco Sensor. We will re-design and miniaturise the fluidic manifold to reduce capital- and per-sample cost, increase the sensitivity of nutrients - nitrate and phospate - by 100-times in both fresh- and sea-waters, and develop new ultra-sensitive reagents for heavy metal detection at enviro ....Improved electrophoretic analyser for water quality monitoring. This proposal will advance the Australian made Eco Detection portable electrophoretic analyser for autonomous monitoring of water chemistry - the Eco Sensor. We will re-design and miniaturise the fluidic manifold to reduce capital- and per-sample cost, increase the sensitivity of nutrients - nitrate and phospate - by 100-times in both fresh- and sea-waters, and develop new ultra-sensitive reagents for heavy metal detection at environmentally regulated levels. This will provide a single platform for at-site near-real-time monitoring of water chemistry for agricultural, mining, water corporations and other industries that use and/or discharge water to the environment. Read moreRead less
Effects of maternal foraging success and oceanographic variation on offspring behaviour and survival in the southern elephant seal. Juvenile survival is the key determinant of mammalian population performance, but the proximate determinants of this have rarely been established in large, long-lived predators. Southern elephant seals, with their concentrated lactation effort and marked separation of energy acquisition (at-sea foraging) and expenditure (on-land lactation) provide an ideal model for ....Effects of maternal foraging success and oceanographic variation on offspring behaviour and survival in the southern elephant seal. Juvenile survival is the key determinant of mammalian population performance, but the proximate determinants of this have rarely been established in large, long-lived predators. Southern elephant seals, with their concentrated lactation effort and marked separation of energy acquisition (at-sea foraging) and expenditure (on-land lactation) provide an ideal model for investigating these factors. In this study, we investigate the partitioning of pre-partum performance (fat acquired in mothers) relative to spatial-temporal variation in ocean productivity and the effect of this expenditure on offspring condition and survival. Here, the final missing link of energy transfer and its effects on offspring will be a major outcome of this project.Read moreRead less
Ecological-epidemiological models of feral swamp buffalo control in northern Australia. This research is locally, nationally and internationally significant because it 1) improves the capacity of the Northern Territory and its traditional aboriginal owners to manage together this prevalent species in an effort to minimise disturbance to native flora and fauna and to understand the long-term implications of continued proliferation, 2) provides a nationally relevant system to monitor and project t ....Ecological-epidemiological models of feral swamp buffalo control in northern Australia. This research is locally, nationally and internationally significant because it 1) improves the capacity of the Northern Territory and its traditional aboriginal owners to manage together this prevalent species in an effort to minimise disturbance to native flora and fauna and to understand the long-term implications of continued proliferation, 2) provides a nationally relevant system to monitor and project the spread of disease through feral animal populations in Australia, and 3) combines quantitative data and robust analytical tools that can be used as a template for solving many broad-scale feral animal problems around the world.Read moreRead less
Community Engagement for Productive Ageing: Models to support rural healthy ageing through the maintenance of community involvement and contribution. Governments at all levels are concerned about the looming social and economic challenges flowing from an ageing population. At present, ageing services are largely focussed on caring for the frail dependent aged. Yet, ultimately, the key to meeting the ageing challenge will lie in how successful we are in supporting our healthy independent aged to ....Community Engagement for Productive Ageing: Models to support rural healthy ageing through the maintenance of community involvement and contribution. Governments at all levels are concerned about the looming social and economic challenges flowing from an ageing population. At present, ageing services are largely focussed on caring for the frail dependent aged. Yet, ultimately, the key to meeting the ageing challenge will lie in how successful we are in supporting our healthy independent aged to stay contributing and productive members of their community. By developing evidence-based interventions that focus on preventing social disengagement before it occurs, the project provides a cost effective approach to ensuring that Australia's rapidly growing aged cohort remain social assets and do not become social burdens.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100017
Funder
Australian Research Council
Funding Amount
$1,231,000.00
Summary
Networked knowledge for repatriation communities. This project aims to build a digital facility that supports the repatriation of Indigenous human remains. Repatriation contributes to reconciliation and Indigenous healing and wellbeing, and has been the most important agent of change in the relationship between Indigenous peoples, museums and the academy over the past 40 years. Successful repatriation requires and produces research materials diverse in type, geography and accessibility. Within a ....Networked knowledge for repatriation communities. This project aims to build a digital facility that supports the repatriation of Indigenous human remains. Repatriation contributes to reconciliation and Indigenous healing and wellbeing, and has been the most important agent of change in the relationship between Indigenous peoples, museums and the academy over the past 40 years. Successful repatriation requires and produces research materials diverse in type, geography and accessibility. Within an Indigenous data-governance framework, this project will gather, preserve and make accessible a critical and extensive record of repatriation information worldwide. The project is expected to support repatriation practice and scholarship and improve the opportunities of repatriation for social good.Read moreRead less
Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of th ....Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of this complex inverse estuary system and its surrounding catchment. The new understanding of the sources, fluxes and fate of nutrients within the bay and the surrounding catchment, arising from this project, is expected to benefit management decision-making and establish a new standard in estuarine water quality investigation.Read moreRead less
Understanding the health effects of landscape burning and biomass smoke in Australian towns and cities. Bushfires are increasingly affecting Australian towns and cities directly and indirectly from episodes of severe air pollution. An approach to manage bushfires is to reduce fuel loads by setting planned fires under stable weather conditions, yet this strategy is controversial because of community concerns about ecological sustainability and negative health impacts from smoke. The relative im ....Understanding the health effects of landscape burning and biomass smoke in Australian towns and cities. Bushfires are increasingly affecting Australian towns and cities directly and indirectly from episodes of severe air pollution. An approach to manage bushfires is to reduce fuel loads by setting planned fires under stable weather conditions, yet this strategy is controversial because of community concerns about ecological sustainability and negative health impacts from smoke. The relative importance of air pollution from planned and unplanned bushfires vs. wood heaters, agricultural burning and other sources of air pollution will be determined. Our study will enable evidence-based bushfire smoke management, help formulate national air quality standards and shape policies regarding biomass smoke and bushfire management.Read moreRead less
Translational research in osteoarthritis: from epidemiological studies to clinical interventions. Currently the only treatment for osteoarthritis is to relieve pain. However, there are some factors that may affect the progression of this disease. This project will examine these factors including inflammation, metabolism, and physical inactivity, and find potential modifying therapies such as vitamin D supplementation for osteoarthritis.
Bushfire smoke and the relationship between human and landscape health. A team of landscape ecologists, environmental chemists and public health specialists will determine the ecological causes and adverse health effects of different levels of bushfire smoke in Darwin. Darwin is an ideal setting for this research because the only source of air pollution is the high incidence of controlled and uncontrolled bushfires during the dry season causing variable air quality: a preliminary study found a ....Bushfire smoke and the relationship between human and landscape health. A team of landscape ecologists, environmental chemists and public health specialists will determine the ecological causes and adverse health effects of different levels of bushfire smoke in Darwin. Darwin is an ideal setting for this research because the only source of air pollution is the high incidence of controlled and uncontrolled bushfires during the dry season causing variable air quality: a preliminary study found a link between smoke pollution levels and asthma. The findings of the proposed research will contribute to improved fire management practices to reduce injurious smoke pollution events and contribute to setting appropriate national air quality standards.Read moreRead less