The Victorian Centre For Applied Biostatistics (VCAB): Building Core Methodological Capacity For Population Health
Funder
National Health and Medical Research Council
Funding Amount
$2,497,184.00
Summary
Biostatistics is the scientific discipline that focusses on the methods used to design and analyse research studies on human health. Doctors and other researchers conduct increasingly complex studies to identify best approaches for the prevention and treatment of disease, and these studies must be underpinned by sound biostatistical methods. This Centre will develop a critical mass of expertise in this under-resourced area around a program of methodological research, translation and training.
Design And Analysis Of Interrupted Time Series Studies In Health Care Research: Resolution Of Methodological Issues
Funder
National Health and Medical Research Council
Funding Amount
$307,125.00
Summary
An interrupted time series (ITS) study involves a population observed on multiple occasions before and after the implementation of an intervention program. However, methods for statistical analysis and designing such studies have not been well developed and many statistical analyses of such studies are flawed. This proposal will investigate appropriate methods for design and analysis, and develop guidelines and software for its implementation by health researchers.
Generating Credible Evidence For Health Care Decision Making: Advancing Methods For Evidence Synthesis And Meta-analysis
Funder
National Health and Medical Research Council
Funding Amount
$360,476.00
Summary
Systematic reviews often underpin recommendations in guidelines and are therefore critical to the translation of research evidence into practice. However, weaknesses in the conduct of reviews can yield biased results, which may lead to patients receiving ineffective or harmful treatments. During my fellowship I will develop and evaluate novel methods to assess and adjust for bias in reviews, to improve the credibility of evidence needed to make well-informed choices about health care.
Does Place Of Birth Influence A Healthy Start To Life?
Funder
National Health and Medical Research Council
Funding Amount
$343,050.00
Summary
There are over 255,000 births in Australia each year and a major challenge in terms of planning and provision is to ensure that these babies are born in hospitals with the appropriate facilities to care for them. International studies suggest that transferring the mother before birth results in better infant outcomes than transferring the baby after birth. In Australia births occur in a range of hospitals, from small rural hospitals to tertiary obstetric and neonatal centres. However, few Austra ....There are over 255,000 births in Australia each year and a major challenge in terms of planning and provision is to ensure that these babies are born in hospitals with the appropriate facilities to care for them. International studies suggest that transferring the mother before birth results in better infant outcomes than transferring the baby after birth. In Australia births occur in a range of hospitals, from small rural hospitals to tertiary obstetric and neonatal centres. However, few Australian studies have looked at infant outcomes based on place of birth. This study will use existing population health data sets to evaluate the provision of care prior to and at birth and the impact it has on infant outcomes up to one year of age. It will also describe for the first time the hospital care utilisation associated with birth and infant health. Information will be obtained from routinely-collected birth, death and birth defect registers, and hospital, midwives and perinatal death review data. Variations in health outcomes for babies may be due to factors that occur before or during pregnancy, or may be due to differences in the care provided at birth. We need to take account of maternal factors to comprehensively assess the role of level of care at birth. We will use statistical techniques to 'predict' infant health outcomes and see if differences between places of birth are real or not. If variations are explained by different levels of care then there is enormous potential for improvement in the provision of pregnancy and newborn services. We will also compare the benefits and consequences of maternal versus neonatal transfer, and assess hospital costs. The results of this study could be applied to direct health services policy and organisational changes to improve pregnancy care and optimise infant outcomes for a healthy start to life.Read moreRead less
Exploring The Contributions Of Individual-, Area- And Service- Level Factors To Indigenous Health Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$486,919.00
Summary
We will use linked hospital and death data, and multilevel models, to estimate the contributions of individual-, area- and service-level factors to inequalities in the outcomes of hospital care between Indigenous and non-Indigenous people. Factors investigated will include socioeconomic status, remoteness, access to primary care services, and hospital characteristics. Conditions explored will include heart disease, stroke, diabetes, chronic obstructive pulmonary disease and asthma.
Discovery Early Career Researcher Award - Grant ID: DE190101382
Funder
Australian Research Council
Funding Amount
$325,000.00
Summary
Optimising digital mental health care: how technology is used in practice. This project aims to develop the first national consensus statement on the use of technology in mental health care in Australia. The project will examine how Australian health practitioners currently use digital therapy programs, and synthesise this data with international evidence and input from Australian government, health service, and digital health experts. This project expects to improve the implementation of digita ....Optimising digital mental health care: how technology is used in practice. This project aims to develop the first national consensus statement on the use of technology in mental health care in Australia. The project will examine how Australian health practitioners currently use digital therapy programs, and synthesise this data with international evidence and input from Australian government, health service, and digital health experts. This project expects to improve the implementation of digital therapy tools using an innovative, theory-driven approach. Expected outcomes of this project include increased and optimal implementation of digital therapy tools among mental health care providers and enhanced capacity within the Australian health system to meet the high demand for services in the community.Read moreRead less
Identifying Risk For Second And Subsequent Pregnancies: A Longitudinal Record Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$586,129.00
Summary
Interventions (eg. induction of labour) or conditions (eg bleeding) in one pregnancy may affect outcomes in the next pregnancy (eg. risk of complications). These relationships are under-investigated. Using population data on over 194,000 women we can look at repeat pregnancies experienced by individual women. We will use this data to investigate whether interventions in one pregnancy affect subsequent birth outcomes (for mother or baby) and whether particular conditions are likely to recur.
Goodness-of-fit Testing Of Log-link Models For Categorical Outcome Data
Funder
National Health and Medical Research Council
Funding Amount
$260,863.00
Summary
Information about the health consequences of exposure to causal factors is obtained from mathematical models of observed data. Incorrect inferences are possible if the model does not adequately represent the data. Relative risk models are recommended for observations over time on a cohort of subjects, but it is not known how best to assess the adequacy of such models. This project will assess the performance of summary measures of goodness-of-fit when applied to relative risk models.
On The Scene: The Epidemiology Of HIV Among Men Who Have Sex With Men (MSM) In Victoria
Funder
National Health and Medical Research Council
Funding Amount
$73,397.00
Summary
This PhD will focus specifically on HIV among men who have sex with men in Victoria in effort to identify factors that may explain recent increases in rates of new HIV diagnoses and explore characteristics associated with HIV risk. It will incorporate surveillance and epidemiological data, examinations of local health promotion and HIV prevention initiatives and incorporate modelling methods for HIV to support HIV prevention programs and inform health and service planning in Australia.