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Interpreting intrusions: Illuminating the cognitive mechanisms that fuel obsessional thought. This project aims to evaluate a theoretical model regarding the causal and maintaining role that cognitive biases play in obsessional thought. Obsessions are common in the general population and negatively impact health and daily functioning. Individuals struggle with their obsessions but are unable to disengage from them. A pressing question is: what makes an obsession so “sticky”? To answer this quest ....Interpreting intrusions: Illuminating the cognitive mechanisms that fuel obsessional thought. This project aims to evaluate a theoretical model regarding the causal and maintaining role that cognitive biases play in obsessional thought. Obsessions are common in the general population and negatively impact health and daily functioning. Individuals struggle with their obsessions but are unable to disengage from them. A pressing question is: what makes an obsession so “sticky”? To answer this question, this project aims to employ a novel, computerised experimental methodology to directly manipulate cognitive processes proposed to underpin obsessions. This methodology will be used to alter key biases proposed to drive obsessional thinking, thus shedding light on core psychological mechanisms.Read moreRead less
Cognitive neuroscience of spatial asymmetry: behaviour, genes and brain imaging. When humans distribute their attention in space, biases or asymmetries of spatial attention exist. Healthy individuals exhibit a processing advantage favouring left space but this advantage is lost in disorders such as unilateral spatial neglect, ADHD and dyslexia. This project will develop novel electrophysiological methods to dissociate the sensory, attentional, decision-making and motoric contributions to spatial ....Cognitive neuroscience of spatial asymmetry: behaviour, genes and brain imaging. When humans distribute their attention in space, biases or asymmetries of spatial attention exist. Healthy individuals exhibit a processing advantage favouring left space but this advantage is lost in disorders such as unilateral spatial neglect, ADHD and dyslexia. This project will develop novel electrophysiological methods to dissociate the sensory, attentional, decision-making and motoric contributions to spatial asymmetries. By interfacing electrophysiology with genetic, neurochemical and brain imaging methods, this project will comprehensively map the biology of spatial asymmetry. This knowledge is vital to developing effective treatments for disorders where atypical patterns of spatial asymmetry index neurological vulnerability.Read moreRead less
Changing the lives of young Australians with emotional disorders using a simple three-step treatment based on cognitive-neuroscience insights. Anxiety and depression are emotional disorders that affect many Australian children and place them at risk of lifelong impairment. The latest evidence from cognitive science and neuroscience shows that these children have maladaptive thinking strategies that lead to avoidance and withdrawal. Capitalising on these basic science insights, this project exami ....Changing the lives of young Australians with emotional disorders using a simple three-step treatment based on cognitive-neuroscience insights. Anxiety and depression are emotional disorders that affect many Australian children and place them at risk of lifelong impairment. The latest evidence from cognitive science and neuroscience shows that these children have maladaptive thinking strategies that lead to avoidance and withdrawal. Capitalising on these basic science insights, this project examines a new treatment, referred to as the 'Emotional Flexibility Program', that targets childhood distress in three simple steps over just four weeks of treatment. This treatment could change the way childhood emotional disorders are treated and prevented, improve the quality of life for thousands of young Australians, and offset the associated economic burden of disease.Read moreRead less
Understanding genetic and environmental risks of emotional disorders in childhood and adolescence. To reduce the burden of mental health disorders in Australia, this project will advance knowledge on genetic and environmental causes of anxiety and related disorders in children and adolescents. The results will allow better identification of children at risk for emotional problems and will identify new ways of tailoring prevention and treatment.
Testing theoretical models of age and disease related changes to inform prevention. Pathological brain changes associated with future cognitive decline become detectable in the 40s or earlier. Yet little is known about what constitutes normal brain ageing in mid-life. Using a number of neuroimaging and epidemiological techniques this project will scrutinise brain and cognitive ageing in middle-age and their significance.
Social relations and social engagement in older adulthood: implications for health, well being and cognition. This project will examine the nature of changes in peoples social networks that occur with age and the effects of these changes on health and well being in later life. The project will use information collected as part of several ongoing Australian studies of ageing and will have implications for social policy.
The development of the social brain in early childhood. This project aims to understand how the human brain develops social and emotional understanding. The brain has remarkable abilities for understanding our social environment, such as inferring other people’s thoughts and feelings. This project will use neuroscience techniques to investigate how brain networks combine to produce social understanding, how this changes throughout child development, and how it relates to complex social behaviour ....The development of the social brain in early childhood. This project aims to understand how the human brain develops social and emotional understanding. The brain has remarkable abilities for understanding our social environment, such as inferring other people’s thoughts and feelings. This project will use neuroscience techniques to investigate how brain networks combine to produce social understanding, how this changes throughout child development, and how it relates to complex social behaviours. This project’s findings could be used to develop educational programmes that enhance empathy and co-operation, strengthen family relationships, promote social inclusion and reduce maladaptive behaviours. It could also guide intervention in brain disorders that affect social understanding.Read moreRead less
Mapping, understanding and manipulating the human brain connectome with MRI. The human brain is an extraordinarily complex network, comprising millions of nerve cells connected by trillions of fibres. Understanding this intricate web of connectivity – the so-called human connectome – has become a central goal of neuroscience and is comparable in scale to the human genome project. This project will develop new brain imaging methods for accurately mapping the connectome. It will investigate how in ....Mapping, understanding and manipulating the human brain connectome with MRI. The human brain is an extraordinarily complex network, comprising millions of nerve cells connected by trillions of fibres. Understanding this intricate web of connectivity – the so-called human connectome – has become a central goal of neuroscience and is comparable in scale to the human genome project. This project will develop new brain imaging methods for accurately mapping the connectome. It will investigate how information is communicated between its different regions and how individual differences in brain network function relate to our genetic make-up. It will also determine whether we can manipulate the function of specific circuits of the connectome in a targeted way, in the hope of developing new treatments for brain disorders.Read moreRead less
A longitudinal study into the development of personal vulnerabilities and well-being in adolescence. This longitudinal study examines the temperament and environmental factors that promote character strengths in adolescents. Character strengths such as empathy and emotion-management skills are potentially teachable and help prevent an adolescent from experiencing difficulties in social, emotional and academic adjustment.
Placing prediction into the fear circuit. How do we predict danger in our world? This project will identify the psychological mechanisms and brain pathways that allow us to learn to fear and to also overcome fear when it becomes pathological.