Discovery Early Career Researcher Award - Grant ID: DE120100729
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Brain connectivity during movement planning and execution in young and older adults. Ageing is associated with a reduced ability to undertake everyday movement tasks, resulting in loss of independence and frequent injuries due to falls. This research will improve our understanding of the brain mechanisms underlying movement control, with the aim of maintaining older people's quality of life and reducing health costs to the nation.
Motor coordination in infancy and its relationship to motor and psychosocial development in childhood. Few studies have examined the impact of early motor development on later development, even though there is evidence to show that these early movements influence later motor ability. Motor development can also impact on cognitive, emotional and social development. The current study has data on early motor ability in over 90 infants which includes children at risk of developmental disorders. We ....Motor coordination in infancy and its relationship to motor and psychosocial development in childhood. Few studies have examined the impact of early motor development on later development, even though there is evidence to show that these early movements influence later motor ability. Motor development can also impact on cognitive, emotional and social development. The current study has data on early motor ability in over 90 infants which includes children at risk of developmental disorders. We will carry out a longitudinal investigation of the relationship between early motor development in infancy on motor and psychosocial development in childhood. The results will provide information on early markers for developmental disorders and appropriate intervention techniques than can be initiated in infancy. Read moreRead less
The influence of resistance training upon movement control in the elderly. The primary aim of this applied research project is to investigate the impact of resistance training in the elderly. We will assess the responses to training that occur in the elderly, and determine the time course and persistence of adaptation. It is anticipated that the knowledge derived will be applied by clinicians and health practitioners in the design of resistance training programmes for the elderly, and thereby en ....The influence of resistance training upon movement control in the elderly. The primary aim of this applied research project is to investigate the impact of resistance training in the elderly. We will assess the responses to training that occur in the elderly, and determine the time course and persistence of adaptation. It is anticipated that the knowledge derived will be applied by clinicians and health practitioners in the design of resistance training programmes for the elderly, and thereby enhance the performance of tasks encountered in daily living.Read moreRead less
Determining the neural mechanisms of visual stimuli and motor responses. This project aims to determine how we select actions to visual cues rapidly, unconsciously and automatically. Learning associations between visual stimuli and motor responses is part of normal development and continues throughout life. Rapid deployment of these actions is often critical for safety yet we have limited knowledge of how the human brain does this. This project will use neuroimaging tools to characterise the spa ....Determining the neural mechanisms of visual stimuli and motor responses. This project aims to determine how we select actions to visual cues rapidly, unconsciously and automatically. Learning associations between visual stimuli and motor responses is part of normal development and continues throughout life. Rapid deployment of these actions is often critical for safety yet we have limited knowledge of how the human brain does this. This project will use neuroimaging tools to characterise the spatial and temporal neural architecture underlying these processes and determine how the dorsal and ventral streams of visual processing, specialised for motor control and recognition respectively, interact in vision-based actions as these actions become learned.Outcomes will provide new frameworks for driving improvement in any domain in which goal-directed actions depend on the rapid processing of visual information, including human-machine interfaces for defence, economic development, education, health, science and technology.Read moreRead less
Facilitatory and inhibitory mechanisms during interlimb coordination in young and older adults. The project seeks to understand how people coordinate their limbs and the factors which limit and enhance this capacity. This is of critical importance because coordination is a dominant deficit in aging and in patients suffering brain insult and neurodegenerative diseases. Disruption of this capacity compromises individual work productivity, mobility and independence. Proficient motor functioning is ....Facilitatory and inhibitory mechanisms during interlimb coordination in young and older adults. The project seeks to understand how people coordinate their limbs and the factors which limit and enhance this capacity. This is of critical importance because coordination is a dominant deficit in aging and in patients suffering brain insult and neurodegenerative diseases. Disruption of this capacity compromises individual work productivity, mobility and independence. Proficient motor functioning is an important lifestyle factor as humans age and deficits in coordinated muscle activity will increase the risk of falls which are the leading cause of injury in elderly adults. Identification of changes in brain processes involved in interlimb coordination will allow for the development of strategies to improve motor functions in the aged.Read moreRead less
Motor control of the upper airway muscle genioglossus. This project aims to evaluate a recent proposal about the motor control of the upper airway muscle Genioglossus. The upper airway muscles, the most complex in the human body, are critical for breathing and speaking, but are not well understood. Genioglossus draws the base of the tongue forward to maintain airway patency. This project will study genioglossus during wakefulness and sleep in normal healthy individuals. It is anticipated that th ....Motor control of the upper airway muscle genioglossus. This project aims to evaluate a recent proposal about the motor control of the upper airway muscle Genioglossus. The upper airway muscles, the most complex in the human body, are critical for breathing and speaking, but are not well understood. Genioglossus draws the base of the tongue forward to maintain airway patency. This project will study genioglossus during wakefulness and sleep in normal healthy individuals. It is anticipated that the project will suggest improved avenues for treatment of sleep related respiratory disorders.Read moreRead less
Understanding the physiological changes accompanying arousal from sleep. This project aims to investigate neural memory in upper airway dilator muscles. Following brief awakening from sleep (arousal), upper airway dilator muscle activity is elevated for 20–30 seconds despite inhibitory stimuli being present. The cause for the elevated activity is unknown. This project aims to investigate whether a form of neural memory contributes to the elevated activity. It expects to demonstrate that arousal ....Understanding the physiological changes accompanying arousal from sleep. This project aims to investigate neural memory in upper airway dilator muscles. Following brief awakening from sleep (arousal), upper airway dilator muscle activity is elevated for 20–30 seconds despite inhibitory stimuli being present. The cause for the elevated activity is unknown. This project aims to investigate whether a form of neural memory contributes to the elevated activity. It expects to demonstrate that arousal can induce a neural memory that is not inhibited by usual stimuli. The findings are expected to increase our understanding of normal human functioning but may also have implications for conditions where upper airway muscles are important such as dysphagia, sleep apnea and numerous other sleep disorders.Read moreRead less
Brain mechanisms of learning in visually-guided movement. Each year 40,000 Australian suffer from stoke with many left with problems of limb function. In understanding and enhancing the conditions that promote motor adaptation, this research will make a significant contribution to the design of programs for rehabilitation of the upper limbs to enhance quality of life and reduced health care costs.