Chronic Kidney Disease In Indigenous Australians: Using Existing Data To Improve Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$303,014.00
Summary
Indigenous Australians not only suffer from a high burden of kidney disease, but also have poorer disease outcomes compared to non-Indigenous Australians. My research program is focused on improving outcomes for Indigenous Australians with kidney disease by using existing health care data to work out where and why their outcomes are poor within the health care system. It will enable us to identify ways to improve health care systems for Indigenous Australians.
Improving Delivery Of Secondary Prophylaxis For Rheumatic Heart Disease: A Stepped-wedge, Community-randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,913,074.00
Summary
Rheumatic heart disease (RHD) is a major health problem in Indigenous communities. Continued progress in controlling RHD requires an understanding of how to improve delivery of regular injections of penicillin - secondary prophylaxis (SP). We will evaluate a systems-based approach to improving delivery of SP, using a stepped-wedge trial in 12 communities in NT and Qld. If successful, this model will provide a practical and transferable model.
Australian Partnership (for) Preparedness Research On InfectiouS (disease) Emergencies (APPRISE)
Funder
National Health and Medical Research Council
Funding Amount
$4,996,416.00
Summary
We have assembled national experts in clinical, laboratory and public health research to ensure Australia is equipped for a coordinated, effective and evidence based response to infectious diseases. This multidisciplinary team will create and share new knowledge to detect, prevent and manage emerging infection threats. We will train a robust cross-sectoral work force and develop sustainable research capacity integrated within the health system to ensure national and regional health security.
1+1- A Healthy Start To Life:Targeting The Year Before And The Year After Birth In Aboriginal Children In Remote Areas
Funder
National Health and Medical Research Council
Funding Amount
$587,272.00
Summary
Indigenous Australians in remote communities are less healthy and more socially disadvantaged than other Australians. This influences the quality of the intrauterine environment. Babies often suffer malnutrition and recurring infections during infancy which are exacerbated by their less than optimal birth status and contribute to chronic conditions (diabetes, cardiovascular disease, renal failure) in adulthood. Existing health services are costly to Government and do not achieve their potential ....Indigenous Australians in remote communities are less healthy and more socially disadvantaged than other Australians. This influences the quality of the intrauterine environment. Babies often suffer malnutrition and recurring infections during infancy which are exacerbated by their less than optimal birth status and contribute to chronic conditions (diabetes, cardiovascular disease, renal failure) in adulthood. Existing health services are costly to Government and do not achieve their potential for promoting health and providing quality care. Evidence suggests redesigned models based on continuity of care, focused, proactive family support and workload reform will improve maternal and infant outcomes. New models need to be developed, costed, implemented and evaluated providing governments with the evidence base to initiate service improvement. Such models will have applicability elsewhere in Australia. Professor Lesley Barclay and her team of researchers from Charles Darwin University will conduct research into developing such a model. The project aims to improve the quality of care for remote dwelling Aboriginal women and infants in the year before, during and the year after birth by providing evidence for, and facilitating changes to, service delivery. This will enhance the potential for the development of resilience and well-being of their children. It will also test if service improvements can improve the health of women and reduce childhood disease and therefore reduce the impact of health conditions occurring in adulthood which have their origins in the early stages of life.Read moreRead less
Improving Health Outcomes For Aboriginal Australians With Chronic Disease Thru Strategies To Reduce Systems Barriers To
Funder
National Health and Medical Research Council
Funding Amount
$2,997,256.00
Summary
The research aims to improve outcomes for Aboriginal people with chronic disease, through strategies of care that address health system barriers. The project aims to understand barriers and then to develop, implement and evaluate appropriate models of care that incorporate policy development and engagement. The project is to incorporate research partnerships and Indigenous sector capacity development.
CENTRE OF RESEARCH EXCELLENCE TO REDUCE INEQUALITY IN HEART DISEASE
Funder
National Health and Medical Research Council
Funding Amount
$2,607,253.00
Summary
There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health ....There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health care services.Read moreRead less
About time; a new biology for the mineralocorticoid receptor . Temporal control of cell function aligns biological pathways with environmental cues and is critical for optimal heath in mammals. This project will shed light on how a hormone receptor, the MR, modulates time keeping of biological clock time in cells. We will bring together cutting edge genetic modals and bioinformatic approaches with a unique set of research models to define the interaction between the MR and the circadian clock a ....About time; a new biology for the mineralocorticoid receptor . Temporal control of cell function aligns biological pathways with environmental cues and is critical for optimal heath in mammals. This project will shed light on how a hormone receptor, the MR, modulates time keeping of biological clock time in cells. We will bring together cutting edge genetic modals and bioinformatic approaches with a unique set of research models to define the interaction between the MR and the circadian clock and its role in the normal biology of the heart. New data will significantly enhance our understanding of the biology of MR and cortisol for the circadian time keeping function in peripheral tissues, and gain a clearer understand how our heart cells adapt to environmental circadian disruptors such as shift work. Read moreRead less
The effect of genomic variants on Indigenous health. The effect of genomic variants on Indigenous health. This project aims to examine the genetic variants introduced by Europeans (and other groups) into the genomes of the Aboriginal Australian population. The rate of metabolic diseases such as diabetes and hypertension is very high in Australia’s Indigenous populations. While an energy-rich Western diet has been suggested as the major cause, the contribution of genomic variants (mutations) rema ....The effect of genomic variants on Indigenous health. The effect of genomic variants on Indigenous health. This project aims to examine the genetic variants introduced by Europeans (and other groups) into the genomes of the Aboriginal Australian population. The rate of metabolic diseases such as diabetes and hypertension is very high in Australia’s Indigenous populations. While an energy-rich Western diet has been suggested as the major cause, the contribution of genomic variants (mutations) remains unclear. Anticipated outcomes are better understandings of both the benign and deleterious variants introduced into Aboriginal Australian populations and how these contribute to disease susceptibility.Read moreRead less
Building An Indigenist Health Humanities Collective. This proposal aims to develop Indigenist Health Humanities as a new and innovative field of inquiry, building an intellectual collective capable of bridging the knowledge gap that hinders current efforts to close the gap in Indigenous health inequality. Bringing together health and the humanities through the particularity of Indigenous scholarship, a deeper understanding of the human experience of health will be developed alongside a greater u ....Building An Indigenist Health Humanities Collective. This proposal aims to develop Indigenist Health Humanities as a new and innovative field of inquiry, building an intellectual collective capable of bridging the knowledge gap that hinders current efforts to close the gap in Indigenous health inequality. Bringing together health and the humanities through the particularity of Indigenous scholarship, a deeper understanding of the human experience of health will be developed alongside a greater understanding of the enablers to building a transdisciplinary collective of Indigenous health researchers. The potential benefits include a more sustainable, relational and ethical approach to advancing new knowledge, advancing research careers and advancing health outcomes for Indigenous people. Read moreRead less
Special Research Initiatives - Grant ID: SR0354696
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
ARC Research Network in Enterprise Information Infrastructure (EII). This research network targets investigation of Enterprise Computing and its infrastructure, with an emphasis on emerging advanced technologies and practices, for large-scale enterprises, government agencies and community groups. EII will bring together the best IT researchers, leading edge users and key IT technology providers to support consolidated, technically sound, integrated and strategically positioned research towards s ....ARC Research Network in Enterprise Information Infrastructure (EII). This research network targets investigation of Enterprise Computing and its infrastructure, with an emphasis on emerging advanced technologies and practices, for large-scale enterprises, government agencies and community groups. EII will bring together the best IT researchers, leading edge users and key IT technology providers to support consolidated, technically sound, integrated and strategically positioned research towards solutions for next generation Enterprise Computing. Web services, the Semantic Web and Service Oriented Computing are fast emerging new disciplines with far reaching impacts. EII will contribute to their growth and to their practical deployment in Australia and beyond. The establishment of EII network will dramatically add value to already supported but often fragmented research projects.Read moreRead less