Quantifying the impact of ambulance diversion for better stroke patient outcomes. It has been established that specialised care of stroke patients can significantly improve their outcomes. However, diverting ambulances to specialised stroke centres may affect the response time for future emergencies. This research aims to model the many complex response time factors and provide a quantitative measure of the impact of diversion.
Determining features that separate groups of protein sequences. This project aims to develop mathematical approaches for determining features that distinguish one group of proteins from another, based on their amino acid sequences. The groups of sequences will reflect different outcomes, so that identifying the fundamental features can result in targeted interventions against the poorer outcome. A simple comparison at each position or of known features can fail to determine robust differentiator ....Determining features that separate groups of protein sequences. This project aims to develop mathematical approaches for determining features that distinguish one group of proteins from another, based on their amino acid sequences. The groups of sequences will reflect different outcomes, so that identifying the fundamental features can result in targeted interventions against the poorer outcome. A simple comparison at each position or of known features can fail to determine robust differentiators and so more complex methods are required. The project will, for example, help identify HIV vaccine targets by comparing early HIV transmission sequences from those in chronic infection. The methods will be applicable to viral proteins where high mutation rates make this task even more complex.Read moreRead less
Evaluating the long-term costs and benefits of community-based initiatives. The ultimate benefit from the research is a more efficient allocation of public funds to provide public services, i.e. an increase in the gain derived from the government budget. The relative advantages of alternative methods of delivering government services are subject to significant uncertainty, which means that policy decisions are often poorly informed. Improvements in the accuracy of predicting the costs and benefi ....Evaluating the long-term costs and benefits of community-based initiatives. The ultimate benefit from the research is a more efficient allocation of public funds to provide public services, i.e. an increase in the gain derived from the government budget. The relative advantages of alternative methods of delivering government services are subject to significant uncertainty, which means that policy decisions are often poorly informed. Improvements in the accuracy of predicting the costs and benefits of complex community-based initiatives will help policymakers identify the set of initiatives that provide the best outcomes for the community they serve, as well as informing the optimal specification of the individual initiatives.Read moreRead less
New theory and methods for robust global optimisation: modern decision-making under uncertain conditions. The project will produce enhanced optimisation methodologies for solving a wide range of industrial and scientific problems that are affected by data uncertainty and are currently too complex to be solved. The work has the potential to improve the quality and the performance of various Australian industries and many areas of scientific research.
Pathways to agri-food supply chains that co-benefit people and nature. This project aims to improve biodiversity outcomes of agricultural food production and consumption, and expects to generate new knowledge about impacts of interventions and shocks on the environment, human health and livelihoods in agri-food systems. This will be achieved using an interdisciplinary approach that accounts for uncertainties in links between farmers, suppliers, consumers and supply-chain outcomes. The expected o ....Pathways to agri-food supply chains that co-benefit people and nature. This project aims to improve biodiversity outcomes of agricultural food production and consumption, and expects to generate new knowledge about impacts of interventions and shocks on the environment, human health and livelihoods in agri-food systems. This will be achieved using an interdisciplinary approach that accounts for uncertainties in links between farmers, suppliers, consumers and supply-chain outcomes. The expected outcome is a value of information framework for identifying nature-friendly policies and actions with co-benefits for human well-being. Benefits include sustainability pathways with win-win outcomes for people and nature, and improved ways of meeting international commitments such as Sustainable Development Goals.Read moreRead less
New Theory and Algorithms for Nonsmooth Optimisation with Application to Integer Programming. Mathematical optimisation plays a key role in a wide variety of applications in business, industry, engineering and science. For example, airlines cannot fly and radiation treatment for cancer cannot be delivered without solving (a series of) optimisation problems. Some classes of optimisation problem are very well solved, with clear mathematical foundations, efficient algorithms, and reliable software ....New Theory and Algorithms for Nonsmooth Optimisation with Application to Integer Programming. Mathematical optimisation plays a key role in a wide variety of applications in business, industry, engineering and science. For example, airlines cannot fly and radiation treatment for cancer cannot be delivered without solving (a series of) optimisation problems. Some classes of optimisation problem are very well solved, with clear mathematical foundations, efficient algorithms, and reliable software implementations. Both nonsmooth and integer optimisation problems have a good mathematical basis, but there are "gaps"; existing methods cannot always solve real industrial problems. This project will deliver better methods, built on better theory, and so will yield better solutions for important applications.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100234
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Exact and hybrid algorithms for the Aircraft Landing Problem. This project aims to develop algorithms with superior guaranteed performance. Aircraft Landing Problems (ALP) are an important class of decision problems. Optimal solution of an ALP is applicable in transportation and health care delivery, benefitting systems experiencing long delays. This project aims to address several of the Australian Government's Science and Research Priorities, focusing on food supply chains, effective operation ....Exact and hybrid algorithms for the Aircraft Landing Problem. This project aims to develop algorithms with superior guaranteed performance. Aircraft Landing Problems (ALP) are an important class of decision problems. Optimal solution of an ALP is applicable in transportation and health care delivery, benefitting systems experiencing long delays. This project aims to address several of the Australian Government's Science and Research Priorities, focusing on food supply chains, effective operation and resource allocation in transport, and better models of health care delivery and services.Read moreRead less
Improving train flows with connected driver advice systems. The project aims to develop new train control theory to determine the efficient movement of multiple trains, and to demonstrate a practical system for coordinating trains, on busy intercity rail corridors. Railways around the world are now deploying driver advice systems developed by the research team and the partner organisation, TTG Transportation Technology. The project is designed to enable these systems to coordinate the movements ....Improving train flows with connected driver advice systems. The project aims to develop new train control theory to determine the efficient movement of multiple trains, and to demonstrate a practical system for coordinating trains, on busy intercity rail corridors. Railways around the world are now deploying driver advice systems developed by the research team and the partner organisation, TTG Transportation Technology. The project is designed to enable these systems to coordinate the movements of many trains on a congested rail network to improve timekeeping, smooth the flow of traffic, increase capacity and reduce energy use.Read moreRead less
Data-Driven Multistage Robust Optimization—the New Frontier in Optimization. Robust optimisation is a powerful technology for decision-making in uncertain environments. Yet, developing numerically certifiable optimisation principles and data-driven methods that can be readily implemented by common computer algorithms remains an elusive goal for multistage robust optimisation. But it is crucial for the practical use of multistage optimisation. This project aims to develop this novel mathematical ....Data-Driven Multistage Robust Optimization—the New Frontier in Optimization. Robust optimisation is a powerful technology for decision-making in uncertain environments. Yet, developing numerically certifiable optimisation principles and data-driven methods that can be readily implemented by common computer algorithms remains an elusive goal for multistage robust optimisation. But it is crucial for the practical use of multistage optimisation. This project aims to develop this novel mathematical theory and methods by extending the investigators' recent award winning advances, including the von Neumann-prizewinning Lasserre-hierarchy approach. Results will provide a foundation and technologies for making superior decisions in the pervasive presence of big data uncertainty, enhancing data-driven innovation in AustraliaRead moreRead less
Real-time scheduling of trains to control peak electricity demand. This project aims to develop new scheduling and control methods that will enable railways to reduce their demand for electricity during peak demand periods, without undue disruption to the timetable.
These new methods and systems will integrate with—and expand the capabilities of—an Australian train control system that is used by railways around the world. This will enable better management of electricity within a region and be ....Real-time scheduling of trains to control peak electricity demand. This project aims to develop new scheduling and control methods that will enable railways to reduce their demand for electricity during peak demand periods, without undue disruption to the timetable.
These new methods and systems will integrate with—and expand the capabilities of—an Australian train control system that is used by railways around the world. This will enable better management of electricity within a region and better use of renewable energy sources, with significant cost savings for railways and the wider community.Read moreRead less