Does Inpatient Weight Restoration Prior To Outpatient Family Therapy Improve Outcomes In Adolescent Anorexia Nervosa?
Funder
National Health and Medical Research Council
Funding Amount
$552,283.00
Summary
This study examines the effect of length of hospital admission for refeeding, prior to manualised outpatient family therapy on outcomes for patients with anorexia nervosa. Subjects will include sixty children and adolescents aged 10 to 18 years admitted to the Children's Hospital at Westmead for medical management of anorexia nervosa. This study aims to randomly allocate and compare outcomes between adolescents with anorexia nervosa admitted for medical stabilisation followed by outpatient famil ....This study examines the effect of length of hospital admission for refeeding, prior to manualised outpatient family therapy on outcomes for patients with anorexia nervosa. Subjects will include sixty children and adolescents aged 10 to 18 years admitted to the Children's Hospital at Westmead for medical management of anorexia nervosa. This study aims to randomly allocate and compare outcomes between adolescents with anorexia nervosa admitted for medical stabilisation followed by outpatient family therapy versus adolescents admitted for full weight restoration followed by outpatient family therapy. Physical and psychological outcomes will be measured at admission to hospital, at the end of the hospital treatment and at the completion of outpatient family therapy and 6 and 12 months after the completion of treatment.Read moreRead less
Assessing Naltrexone Implant Or Methadone Maintenance Treatment On Mental And Physical Health Outcomes In Heroin Users
Funder
National Health and Medical Research Council
Funding Amount
$216,200.00
Summary
The WA hospital data linkage system (DLS) will be used to assess differences in the mental and physical health of dependent heroin users prior to and post naltrexone implant or methadone maintenance treatment (MMT). MMT is the best established pharmacotherapy for the management of heroin dependence but oral naltrexone is gaining some acceptance. Currently funded by NHMRC, we are looking at outcomes with oral naltrexone using DLS data. Although effective in blocking heroin, management via oral na ....The WA hospital data linkage system (DLS) will be used to assess differences in the mental and physical health of dependent heroin users prior to and post naltrexone implant or methadone maintenance treatment (MMT). MMT is the best established pharmacotherapy for the management of heroin dependence but oral naltrexone is gaining some acceptance. Currently funded by NHMRC, we are looking at outcomes with oral naltrexone using DLS data. Although effective in blocking heroin, management via oral naltrexone has proved problematic, with medicine non compliance and relapse common. Surgical insertion of subcutaneous implants is an alternative method of naltrexone delivery. 441 heroin users have received naltrexone implants (3.4g) under Special Access in WA. Although naltrexone implants have yet to be comprehensively assessed, early results are encouraging. Pilot study data has shown a significant reduction in hospital emergency department (ED) attendance for accidental overdose, and mental health events following implant. The aim of this study is to more rigorously assess outcomes associated with implants compared to heroin dependent persons treated by MMT . The DLS collates general hospital and mental health admissions plus mortality data for individuals. This allows the health of an individual to be monitored over time. An electronic version of hospital ED data has recently become available. The study will validate these records by comparing the electronic data against hospital ED records for the implant group. We will then combine the electronic ED and DLS data. Morbidity and mortality rates for heroin users are significantly greater than those for the general population. If the preliminary findings are replicated, naltrexone implants may offer significant benefits over current pharmacotherapies in reducing general and psychiatric morbidity in dependent heroin users.Read moreRead less
Enhancing The Capacity Of Mental Health Services To Review, Personalise And Intervene Early Through Implementation Of Real-time Outcome Monitoring
Funder
National Health and Medical Research Council
Funding Amount
$181,065.00
Summary
By monitoring functioning and symptom changes experienced by severe mental illness patients in their living environments, mental health services can identify those experiencing decline earlier and hence deliver appropriate and timely interventions. However, monitoring is currently poorly implemented in Australian mental health services and inadequately supported by national policy. The applicant proposes to address this evidence-practice gap through a mobile phone-based monitoring system.
Standalone Internet Anxiety Treatment For Stuttering: A Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$516,339.00
Summary
Anxiety-related mental health disorders, particularly social phobia, are common comorbid conditions among adults who stutter. This project establishes randomised controlled trial evidence for the psychological benefits of our Internet CBT treatment. This project also establishes whether our Internet CBT treatment reduces stuttering severity when combined with speech treatment. The design is an open plan, parallel, pragmatic randomised controlled trial.
Long-term Outcome Of Individuals Who Had A First-episode Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$1,344,905.00
Summary
The long-term illness course and outcomes of patients treated for first episode psychosis are poorly understood especially in terms of important domains such as social and vocational functioning, physical health, and quality of life. This treated cohort study of a sample of 786 patients, 15 years after their first episode of psychosis will be one of the longest and largest conducted to date. Results of the study will inform clinical practice and policy development.
Developing Better Models Of Outcome For Psychotic Disorders
Funder
National Health and Medical Research Council
Funding Amount
$458,695.00
Summary
Research on psychosis has been focused on developing treatments for hallucinations and delusions. However, ‘outcome’ is multifaceted and must embrace functioning, and quality of life. A/Prof Cotton will develop models will comprehensively capture ‘whole person’ outcomes for people who have experienced psychosis. Understanding how the disease impacts on the individual will enable better service planning, and refinement and development of treatments for patients with psychosis.
The Mental Health Of School-Age Children Who Stutter
Funder
National Health and Medical Research Council
Funding Amount
$154,781.00
Summary
Children who stutter face considerable social disadvantages and negative consequences. Adults who stutter have been found to report a significant rate of mental health disorders, yet virtually nothing is known about the presence of such problems in children who stutter. This study will evaluate the prevalence and impact of mental disorders among school-age children who stutter. This research is essential for the provision of adequate speech and psychological treatments for children who stutter.
A Randomised Controlled Trial Of A Mindfulness Intervention For Men With Advanced Prostate Cancer
Funder
National Health and Medical Research Council
Funding Amount
$729,841.00
Summary
Approximately 22,000 Australian men alive today have advanced prostate cancer. By comparison to men with localised prostate cancer, men with advanced disease report higher levels of psychological distress and poorer quality of life, and have an increased risk of suicide. This study will trial a remote access mindfulness-based cognitive therapy intervention aimed at improving mental health outcomes and wellbeing for men with advanced prostate cancer.
Suicide prevention and management of deliberate self-harm: randomised control trial of an assertive engagement, brief psychotherapy and community linkage model. Suicide is the second commonest cause of death by injury in Australia. Suicide prevention is an important public health priority but rates remain high. People who have previously attempted suicide are most likely to kill themselves. Most suicidal people attend emergency departments where they get inadequate treatment for their psychologi ....Suicide prevention and management of deliberate self-harm: randomised control trial of an assertive engagement, brief psychotherapy and community linkage model. Suicide is the second commonest cause of death by injury in Australia. Suicide prevention is an important public health priority but rates remain high. People who have previously attempted suicide are most likely to kill themselves. Most suicidal people attend emergency departments where they get inadequate treatment for their psychological and social problems and remain depressed and suicidal. This project will test the effectiveness of a new psychological and social treatment to reduce the depression and link suicidal people with community supports. If successful, this treatment could be provided in any emergency department and help decrease suicide rates in Australia.Read moreRead less