HIV Assembly, Transport, Egress And Transfer From Infected Dendritic Cells
Funder
National Health and Medical Research Council
Funding Amount
$511,629.00
Summary
HIV-AIDS is the fourth leading killing disease worldwide, with the disease burden shifting towards women. Study of the HIV life cycle in cells known to be targetted during HIV transmission is key towards designing additional preventative measures in the form of topical gels known as microbicides. Mapping of the basic pathways of viral transport within such cells, will aid further drug discovery and-or appropriateness of use of existing drugs in microbicide formulations.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100121
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Three-dimensional super-resolution nanophotonic fabrication facility. This stimulated emission depletion microscopy nanophotonic fabrication facility will be the first nanophotonic fabrication facility that is able to achieve optical resolution far beyond the diffraction limit, which will facilitate breakthroughs in cutting-edge nanotechnology research areas.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100199
Funder
Australian Research Council
Funding Amount
$367,900.00
Summary
Advanced Synthesis System for Two-Dimensional Nanomaterials. Advanced synthesis system for two-dimensional nanomaterials:
This project aims to establish the first synthesis facility in Australia for growing large-area and atomically thin two-dimensional (2-D) nanomaterials including graphene, boron nitride, metal dichalcogenides, metal oxide and nitride nanosheets. Such materials are emerging and innovative materials that possess many properties desirable for energy, electronic, biological, and ....Advanced Synthesis System for Two-Dimensional Nanomaterials. Advanced synthesis system for two-dimensional nanomaterials:
This project aims to establish the first synthesis facility in Australia for growing large-area and atomically thin two-dimensional (2-D) nanomaterials including graphene, boron nitride, metal dichalcogenides, metal oxide and nitride nanosheets. Such materials are emerging and innovative materials that possess many properties desirable for energy, electronic, biological, and environmental related applications. This facility is designed to underpin breakthrough science by providing high-quality large-sized materials to researchers for both fundamental and application research. This new synthesis capability would foster advances in the fundamental understanding of 2-D nanostructures and the development of devices with broad applications in energy conversion and storage, environmental protection, and life sciences.Read moreRead less
The Interaction Between Sexually Transmissible Infections And Human Immunodeficiency Virus Infection In Homosexual Men
Funder
National Health and Medical Research Council
Funding Amount
$635,931.00
Summary
This project examines the inter-relationship between HIV infection and sexually transmitted infections (STIs) in homosexual men. The overall goal of the projet is to inform the development of STI prevention and treatment strategies which may be important in reducing HIV incidence in this population. Homosexual men comprise over 80% of people diagnosed with HIV infecton in Australia, and in many developed nations are one of the largest groups affected by HIV. Rates of other STIs are also increase ....This project examines the inter-relationship between HIV infection and sexually transmitted infections (STIs) in homosexual men. The overall goal of the projet is to inform the development of STI prevention and treatment strategies which may be important in reducing HIV incidence in this population. Homosexual men comprise over 80% of people diagnosed with HIV infecton in Australia, and in many developed nations are one of the largest groups affected by HIV. Rates of other STIs are also increased in homosexual men. Currently, HIV rates are increasing in Australia and in many developed countries. We are in need of new and effective methods of HIV prevention. Data in heterosexuals suggest that where STIs are common, the early detection and treatment of these infections may help reduce HIV incidence. There are few data on this relationship in homosexual men. We propose to utilise an existing Sydney cohort of homosexual men to collect data on biologic tests for STIs, history of recent diagnosis of STIs, and symptoms, to allow a comprehensive description of the epidemiology of STIs and their overlap with HIV. The quality of data on the interaction between HIV and STIs in this cohort will be superior to any previously collected in homosexual men, as it will include data on self-reported doctor diagnosed illness, state of the art biologic testing, and symptom data, for the full spectrum of important STIs. The results of this study will be helpful in determining strategies for HIV and STI screening, education and control in the population which comprises the great majority of cases of HIV infection in Australia, and one of the largest risk groups for HIV infection in the developed world. Screening coupled with treatment of asymptomatic STIs may be an effective new approach to HIV prevention in this population.Read moreRead less
Hot carrier cooling mechanisms in nano structures. This project aims to systematically investigate possible mechanisms of hot carrier cooling in nano structures and to identify the most dominant mechanisms. These are important for efficient hot carrier solar cells and thermoelectrics. This project will develop new physics to understand hot carrier dynamics in nano structures. This project is expected to result in photovoltaic systems with a lower balance of system and levelised cost of electrici ....Hot carrier cooling mechanisms in nano structures. This project aims to systematically investigate possible mechanisms of hot carrier cooling in nano structures and to identify the most dominant mechanisms. These are important for efficient hot carrier solar cells and thermoelectrics. This project will develop new physics to understand hot carrier dynamics in nano structures. This project is expected to result in photovoltaic systems with a lower balance of system and levelised cost of electricity compared to conventional technologies. This should boost solar industry, create green jobs and reduce greenhouse gas emissions.Read moreRead less
Oxide-semiconductor epitaxy: towards next generation nanoelectronics. This project aims to integrate high quality functional oxide heterostructures with semiconductor platforms and address the fundamental obstacles in oxides for highly efficient and high-speed transistor applications by engineering their electronic band structures. The project aims to establish a bridge between the diverse electronic properties of oxides and the established semiconductor platform, and generate new devices and fu ....Oxide-semiconductor epitaxy: towards next generation nanoelectronics. This project aims to integrate high quality functional oxide heterostructures with semiconductor platforms and address the fundamental obstacles in oxides for highly efficient and high-speed transistor applications by engineering their electronic band structures. The project aims to establish a bridge between the diverse electronic properties of oxides and the established semiconductor platform, and generate new devices and functionalities. Expected outcomes include epitaxial functional oxides on Gallium arsenide with ultrahigh, room-temperature sheet electron mobility and a comprehensive understanding of its microscopic origin. This will fundamentally change the route toward novel transistors based on high speed and low energy oxide electronics.Read moreRead less
Modelling The Interaction Between Sexually Transmitted Infections And HIV Transmission To Inform Public Health Policy
Funder
National Health and Medical Research Council
Funding Amount
$543,624.00
Summary
Other sexually transmitted infections (STIs) increase the risk of acquiring or transmitting HIV. Using mathematical models the population level effects of this increased risk will be investigated. This work will inform the design of effective and efficient STI treatment programs that aim to reduce the number of HIV infections in Australian gay men, prevent HIV epidemics in Aboriginal and Torres Strait Island communities, and slow the growth of HIV in Papua New Guinea.