Low Cost High Precision Radiotherapy: A Synergistic Framework For Tumour Tracking During Treatment
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Advances in technology have enabled radiotherapy to become more sophisticated and more efficient at treating cancer. Yet, despite its sophistication, today radiotherapy suffers from a major problem: whilst we routinely image patients prior to treatment, no anatomical information is available during treatment. This project aims to solve this problem by making use of a number of sensors that are already available in a radiotherapy to track the tumours positions during treatment, when it counts.
Real-time In-vivo Imaging During Lung Cancer Radiotherapy
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Lung tumours move in clinically significant and unpredicable ways. Current radiotherapy is limited by the lack of real-time imaging to monitor tumour motion. The aim of this project is to develop and clinically implement Real-time In-vivo Imaging to enable motion-adaptive radiotherapy and thereby improve treatment outcomes. Real-time In-vivo Imaging is a software technology that will be applicalbe to 90% of modern radiotherapy systems globally and will enable wide access to advanced cancer care.
Development Of A Chronically Implantable, Miniaturised Device For Monitoring Ventricular Function, To Assist Tracking An
Funder
National Health and Medical Research Council
Funding Amount
$335,000.00
Summary
Heart failure (HF) is increasing - with ~5million sufferers (1-3rd in New York Heart Association Class III-IV i.e. severe cases) in the US alone, and ~12-15 million worldwide. Its management consumes health resources and strains sufferers, families and institutions. The proposed monitoring-management device, chronically implanted by minimally invasive surgery, will track the heart’s pumping pattern. It will allow informed decisions to optimise therapy, thereby improving Quality of Life (QOL), de ....Heart failure (HF) is increasing - with ~5million sufferers (1-3rd in New York Heart Association Class III-IV i.e. severe cases) in the US alone, and ~12-15 million worldwide. Its management consumes health resources and strains sufferers, families and institutions. The proposed monitoring-management device, chronically implanted by minimally invasive surgery, will track the heart’s pumping pattern. It will allow informed decisions to optimise therapy, thereby improving Quality of Life (QOL), decreasing hospitalisations and decreasing healthcare costs. We aim to develop a small, chronically and easily implantable device to track changes in heart function in HF patients.Read moreRead less
InforMS – An Electronic Patient-driven Health Care Model With Digital Biomarker Monitoring That Improves The Clinical Care Of People With MS.
Funder
National Health and Medical Research Council
Funding Amount
$703,705.00
Summary
Clinicians are lacking timely and sensitive data to detect treatment failure in MS. We will create a paradigm shift in MS care by developing an electronic patient-centred health care system, ‘InforMS’, that becomes a “one-stop-shop” management system which empowers and activates people with MS to collect invaluable time-sensitive monitoring data. We will test InforMS on around 3,000 people with MS to measure uptake and ensure it supports health improvements and changes to clinical practice.
The Role Of HIV Infection Of Astrocytes In The Development Of HIV Associated Dementia
Funder
National Health and Medical Research Council
Funding Amount
$144,250.00
Summary
Dementia is an extremely common problem in the late stages of Human Immunodeficiency Virus (HIV) infection. HIV-associated dementia is the most common cause of dementia in people under 40 years of age. Despite the development of very good drugs to attack the virus, HIV-associaed dementia continues to be a major clinical problem. We are looking at the reasons why some people infected with HIV become demented and others do not. We are also looking at how best to prevent the development of dementia ....Dementia is an extremely common problem in the late stages of Human Immunodeficiency Virus (HIV) infection. HIV-associated dementia is the most common cause of dementia in people under 40 years of age. Despite the development of very good drugs to attack the virus, HIV-associaed dementia continues to be a major clinical problem. We are looking at the reasons why some people infected with HIV become demented and others do not. We are also looking at how best to prevent the development of dementia. We believe that astrocytes (an important brain cell that supports neurons) play a very important role in the development of HIV-associated dementia. With an improved understanding of the steps leading to dementia we can better plan treatments to prevent the development of this devastating complication of HIV-AIDS.Read moreRead less