Guaranteeing Survival Into Adulthood, Physical Health And Psychological Well-being To Children Born With Single Ventricles.
Funder
National Health and Medical Research Council
Funding Amount
$342,773.00
Summary
Being born with a single pumping heart chamber is the most severe heart condition but thanks to several operations we can see them survive. A growing population of young functional adults now face an uncertain future and we have no options for them. A/Pr Y d’Udekem is a leading paediatric cardiac surgeon. His research aims to provide the medications, reinterventions and artificial hearts that are necessary to give them a longer and fulfilling life.
Better Care Of Heart And Lung Disease For Aboriginal And Torres Strait Islander People In Rural And Remote Australia
Funder
National Health and Medical Research Council
Funding Amount
$380,583.00
Summary
Lung and heart disease are major contributors to the Aboriginal Australian and Torres Strait Islander health gap. This is even more so in remote and regional Australia. This Fellowship will generate new knowledge regarding how best to prevent, diagnose and treat heart and lung disease in this setting. Based in Alice Springs, it will bring together researchers and health care providers across northern and Central Australia and link them with our leading national research institutes.
From Fundamental Mechanistic Discoveries To Strategic Methods For Early Detection And Treatment Of Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$412,419.00
Summary
I am an interventional cardiologist whose research program spans from biomedical discovery, to new markers of early cardiovascular disease and clinical trials of new therapy. We are particularly focused on novel strategies to help patients who suffer from heart attack despite having no standard risk factors. I lead a team of cross-disciplinary researchers. A Practitioner Fellowship will help me to achieve international impact against the leading cause of death and disability in our community.
New Approaches To The Management Of Atrial Fibrillation
Funder
National Health and Medical Research Council
Funding Amount
$577,189.00
Summary
Atrial fibrillation is the most common heart rhythm disorders and is now a common cause of hospitalisation in Australia. It can lead to devastating complications such as stroke and heart failure. This fellowship will under take a series of randomised studies to define new therapeutic strategies for management of atrial fibrillation. It aims to establish lifestyle and preventative measures into the mainstream for the management and prevention of this condition.
Atrial fibrillation (AF) has reached epidemic proportions. It results in significant burden to the individual and community with palpitations, falls, strokes, and heart failure which have contributed to an exponential rise in health care usage and hospitalisation. This application will focus on the optimal management of AF with a focus not only on therapeutics but importantly on the prevention of the arrhythmia and minimising hospitalisation.
Trials of numerous agents to slow the progression of Parkinsons disease have provided ambiguous or negative results despite having good preliminary evidence for their efficacy. The most likely reason is that many nerve cells are already destroyed by the time of diagnosis. Thus effective therapies may be most (and possible only) effective when administered in the presymptomatic stages of disease. This proposal is directed at developing method to detect early presymptomatic Parkinsons disease.
Mechanisms, Biomarkers And New Therapies For Abdominal Aortic Aneurysm
Funder
National Health and Medical Research Council
Funding Amount
$551,370.00
Summary
Approximately 5% of men and 1% of women aged over 60 years develop artery weakening. The management of artery weakening is currently focused on radiological imaging and surgery. In this fellowship work will be performed to better understand the mechanisms involved in artery weakening, assess new ways of monitoring disease progression and evaluate new medical therapies. It is envisaged that the work will identify a number of new management stratergies for this common condition.
Advances in positron emission tomography now allow specific pathological features of many brain diseases such as Alzheimer's disease to be measured with a brain scan during life. This Fellowship will assist Professor Rowe and his team in their world leading work on new PET scanning techniques to improve diagnosis and assist the development of treatment for Alzheimer's and other degenerative diseases of the brain.
Developing Improved Management For Peripheral Artery Diseases
Funder
National Health and Medical Research Council
Funding Amount
$569,219.00
Summary
~1 million Australians have peripheral artery disease. The current application is for a Practitioner Fellowship to support my research aimed at improving care of artery disease. The aim of the work is to develop improved management approaches for patients with blocked and weakened arteries. This work is particularly important given the recognised management deficiencies for patients with artery disease and the relative little research being undertaken in this area.
Understanding Early Life Risk Factors For Inflammation In The Rising Predisposition For NCDs
Funder
National Health and Medical Research Council
Funding Amount
$568,892.00
Summary
In 2011 the UN General Assembly identified the rise in non-communicable diseases (NCDs) as a major global threat, and prioritized preventive strategies against diseases like obesity, diabetes, heart disease, allergy and asthma. Common risk factors for these inflammatory diseases begin early in life, the most logical time for prevention. Our international interdisciplinary network aims to improve health and prevent NCDs by early interventions that reduce inflammation over the life-course.