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The role of Fld1p protein in lipid droplet formation and growth in the yeast Saccharomyces cerevisiae. This project aims to characterize Fld1p/seipin, an important protein that controls lipid storage in the form of lipid droplets. Knowing the molecular function of Fld1p will provide important insights into how lipid droplets originate and grow. Such knowledge will help improve the quality and quantity of oil and biodiesel production.
Characterisation of novel gene products that regulate phospholipid metabolism and lipid droplet formation in the yeast saccharomyces cerevisiae. This project aims to study gene products that control lipid storage in the form of lipid droplets. The biogenesis and composition of lipid droplets in plant seeds or algae determine the quantity and quality of oil/biodiesel production.
Discovery Early Career Researcher Award - Grant ID: DE130101168
Funder
Australian Research Council
Funding Amount
$364,900.00
Summary
Enhancement of light-driven electricity generation by cyanobacteria: en route to biosolar panels. Some species of naturally occurring cyanobacteria (blue-green algae) exhibit a special metabolic feature, which enables them to convert sunlight into electricity. This project will unveil the chemical and biological secrets behind this process and will lead to the creation of the first entirely biological solar panel.
Australian Laureate Fellowships - Grant ID: FL170100086
Funder
Australian Research Council
Funding Amount
$2,924,858.00
Summary
Methane bioconversion to liquid chemicals. This project aims to develop a suite of leading-edge biotechnology solutions to enable the cost-effective production of liquid chemicals from biogas. This will create a much stronger economic driver for biogas production from organic wastes, by significantly increasing the value of biogas compared to its current use for power generation. With a multi-disciplinary approach, the project will substantially advance the fundamental science in the exciting an ....Methane bioconversion to liquid chemicals. This project aims to develop a suite of leading-edge biotechnology solutions to enable the cost-effective production of liquid chemicals from biogas. This will create a much stronger economic driver for biogas production from organic wastes, by significantly increasing the value of biogas compared to its current use for power generation. With a multi-disciplinary approach, the project will substantially advance the fundamental science in the exciting and highly valuable area of anaerobic microbial conversion of methane, the least understood process in the global carbon cycle. This transformational research has a strong potential to create a new biotechnology sector producing high-value chemicals from methane, and will propel Australia to the forefront of sustainable resources research.Read moreRead less
The cell wall substrate delivery mechanisms in plants. This project aims to study the delivery of substrates plants need to biosynthesise sugar polymers. Sugar polymers play key structural and functional roles in plant development and determine quality for all plant-based products including food, textile fibres, building materials and renewable biomass. However, unknown mechanisms regulate and control the transport mechanisms that deliver the building blocks for polysaccharide biosynthesis. This ....The cell wall substrate delivery mechanisms in plants. This project aims to study the delivery of substrates plants need to biosynthesise sugar polymers. Sugar polymers play key structural and functional roles in plant development and determine quality for all plant-based products including food, textile fibres, building materials and renewable biomass. However, unknown mechanisms regulate and control the transport mechanisms that deliver the building blocks for polysaccharide biosynthesis. This project is expected to increase understanding of nucleotide sugar transport and develop and enhance the biological toolbox for applications involving modelling and engineering of plants, synthesis of industrial biopolymers and production of functional foods.Read moreRead less
The role of phospholipids in the biogenesis of lipid droplets. The general aim is to elucidate the fundamental molecular mechanisms that govern the biogenesis/formation of the lipid droplets. Lipid droplets store sterol esters and/or triacylglycerols, two major storage lipids that play key roles in cellular and whole body lipid metabolism. Lipid droplets are also the core components of plant oil and biodiesel. Little is known about how lipid droplets are generated. The proposed work will examine ....The role of phospholipids in the biogenesis of lipid droplets. The general aim is to elucidate the fundamental molecular mechanisms that govern the biogenesis/formation of the lipid droplets. Lipid droplets store sterol esters and/or triacylglycerols, two major storage lipids that play key roles in cellular and whole body lipid metabolism. Lipid droplets are also the core components of plant oil and biodiesel. Little is known about how lipid droplets are generated. The proposed work will examine the synthesis of certain lipid intermediates such as phosphatidic acid, and their impact on the biogenesis of lipid droplets from the endoplasmic reticulum. Such fundamental new knowledge on how cells store neutral lipids will provide new strategies for enhancing plant oil and biodiesel production. Read moreRead less