A New Direction For TB Control In Highly Endemic Countries: A RCT Of Active Case Finding
Funder
National Health and Medical Research Council
Funding Amount
$1,362,910.00
Summary
Tuberculosis is the number 1 health problem in Vietnam . Many people with TB do not know they have the disease but are infectious to others. Hence, the disease continues to spread. This project will investigate the role of x-ray screening to detect and treat more people with TB, particularly those who do not have symptoms. This may be an important element of future TB control programs in Vietnam and elsewhere in our region.
Thai Health-Risk Transition: A National Cohort Study - Phase II
Funder
National Health and Medical Research Council
Funding Amount
$1,662,829.00
Summary
We are conducting a pioneering collaborative longitudinal study of population health in Thailand, following over time more than 80,000 adults living throughout the country. We repeatedly measure a wide array of health risks and outcomes. We capture information on the health-risk transition underway in Thailand as the population experiences the new burden of disease associated with economic development and modernisation. We team up with policy makers for national responses to lower the burden.
A Randomized Clinical Trial Comparing Effectiveness Of 4RIF And 9INH For Treatment Of Latent TB Infection
Funder
National Health and Medical Research Council
Funding Amount
$496,875.00
Summary
Treatment of latent tuberculosis infection (LTBI) is one intervention that is known to prevent the occurrence of active TB. Current treatment is based on a six to nine month course of isoniazid. The treatment has side effects in some people and many people do not complete the treatment. The present study is to test an alternative treatment regimen (4 months of rifampicin) which has fewer side-effects and is more likely to be completed.
Eucalypt growth in past and future environments - a novel approach to understanding the impacts of atmospheric CO2 and climate. The impact of climate change and rising atmospheric CO2 on Australia's plantation and native forests is a major concern for government and land managers. These forests are important for environmental, aesthetic, and economic purposes, including carbon sequestration and trading. Forests use large amounts of water, reducing stream flow and water supplies for rural and u ....Eucalypt growth in past and future environments - a novel approach to understanding the impacts of atmospheric CO2 and climate. The impact of climate change and rising atmospheric CO2 on Australia's plantation and native forests is a major concern for government and land managers. These forests are important for environmental, aesthetic, and economic purposes, including carbon sequestration and trading. Forests use large amounts of water, reducing stream flow and water supplies for rural and urban communities. Knowledge generated from the proposed project will provide insight into mechanisms driving productivity and water use of forests in current and future environments. The knowledge will be used by land managers and government to develop strategies to cope with future impacts of climate change.Read moreRead less
A novel cooperative global information system for healthcare. This project will develop a global model for healthcare based on the groundbreaking Protocol Hypothesis Testing (PHT) system, allowing expert groups of clinicians to create and share knowledge across organizations. The PHT is a unique functioning knowledge management system that allows clinicians to record patient and treatment data as it is generated in clinical practice and applies scientific methods to generate clinical knowledge, ....A novel cooperative global information system for healthcare. This project will develop a global model for healthcare based on the groundbreaking Protocol Hypothesis Testing (PHT) system, allowing expert groups of clinicians to create and share knowledge across organizations. The PHT is a unique functioning knowledge management system that allows clinicians to record patient and treatment data as it is generated in clinical practice and applies scientific methods to generate clinical knowledge, all in real-time. The project will develop and test a framework for the PHT system to be used cooperatively by expert groups across virtual organizations, refining the PHT system in the process.Read moreRead less
Quantifying tree and soil respiration and their responses to global change. The Australian Greenhouse Office, as well as independent analysis, recognizes that belowground processes must be better quantified if Australia's contributions to atmospheric concentrations of greenhouse gases (GG) are to be firmly based. A major issue is the lack of dedicated research focused on soil and plant root emissions of GG and, in particular, a lack of testing of methodologies suited to Australian soils and con ....Quantifying tree and soil respiration and their responses to global change. The Australian Greenhouse Office, as well as independent analysis, recognizes that belowground processes must be better quantified if Australia's contributions to atmospheric concentrations of greenhouse gases (GG) are to be firmly based. A major issue is the lack of dedicated research focused on soil and plant root emissions of GG and, in particular, a lack of testing of methodologies suited to Australian soils and conditions. This project will address these concerns. We will also be addressing the clear need for further training of PhD qualified researchers in the field of climate change. Read moreRead less
How will Eucalypt tree architecture and growth adapt to future atmospheric CO2 and drought? This work is fundamental to understanding how growth and water use by Australia's forests will be modified in the future by global change. The changes in tree leaf area and canopy structure that we seek to understand will determine forest responses to increasing atmospheric CO2 and drought. It is essential to study these changes on Australian species, because they differ from forest species elsewhere in h ....How will Eucalypt tree architecture and growth adapt to future atmospheric CO2 and drought? This work is fundamental to understanding how growth and water use by Australia's forests will be modified in the future by global change. The changes in tree leaf area and canopy structure that we seek to understand will determine forest responses to increasing atmospheric CO2 and drought. It is essential to study these changes on Australian species, because they differ from forest species elsewhere in having been largely shaped by water availability. This fundamental work will flow into predictions of future forest growth and water use in Australia, with consequences for land and water resource management as well as forestry.Read moreRead less
CARDIAC-ARIA : Measuring the accessibility to cardiovascular services in rural and remote Australia via applied geographical spatial technology (GIS). Despite significant improvements in the cardiovascular health of Australians, Cardiovascular Disease (CVD) continues to impose a heavy burden on Australians in terms of cost,disability and death. Recent evidence suggests that mortality from CVD increases with increasing remoteness. Rates are reported to be between 20% and 50% higher in rural areas ....CARDIAC-ARIA : Measuring the accessibility to cardiovascular services in rural and remote Australia via applied geographical spatial technology (GIS). Despite significant improvements in the cardiovascular health of Australians, Cardiovascular Disease (CVD) continues to impose a heavy burden on Australians in terms of cost,disability and death. Recent evidence suggests that mortality from CVD increases with increasing remoteness. Rates are reported to be between 20% and 50% higher in rural areas compared to major cities. This project, with its extensive use of Geographic Information Systems (GIS) technology, will rank 11,338 rural and remote population centres to identify geographical 'hotspots' where there is likely to be a mismatch between the demand for and actual provision of cardiovascular services.Read moreRead less