Early Career Industry Fellowships - Grant ID: IE230100040
Funder
Australian Research Council
Funding Amount
$447,127.00
Summary
Unravelling the genetics of Kangaroo paws for climate-resilient gardens. The project will produce the first DNA-anchored plant lineage map of Kangaroo paws and gain novel insights into their resilient growth characteristics. Using novel genome and data-driven strategies, this project addresses the knowledge gap around the genetic heirloom of more than 200 iconic Kangaroo paw varieties to speed up the breeding of new varieties with enticing leaf patterns and flower colour combinations. While unra ....Unravelling the genetics of Kangaroo paws for climate-resilient gardens. The project will produce the first DNA-anchored plant lineage map of Kangaroo paws and gain novel insights into their resilient growth characteristics. Using novel genome and data-driven strategies, this project addresses the knowledge gap around the genetic heirloom of more than 200 iconic Kangaroo paw varieties to speed up the breeding of new varieties with enticing leaf patterns and flower colour combinations. While unravelling the inheritability and breeding barriers, immediate industry adoption will boost horticultural breeding programs long-term. This project uses cutting-edge science to enhance industry capacity for providing new Kangaroo paws for climate-resilient urban green spaces on the national and international market.Read moreRead less
Identification Of Glaucoma Susceptibility Variants By Exome Sequencing In Extended Pedigrees Showing Prior Evidence Of Gene Segregation.
Funder
National Health and Medical Research Council
Funding Amount
$694,002.00
Summary
Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for tr ....Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for treatment or diagnosis.Read moreRead less
Cellular genomic approach to the pathogenesis of multiple sclerosis. This project compares the levels of gene usage in two important immune cell types between patients with multiple sclerosis and people who do not have the disease. It aims to identify the molecular basis for the disease, in order to identify new diagnostic, preventative and treatment options.
A Genome-wide Association Study In 2000 Glaucoma Cases With Matched Controls Using Equimoloar DNA Pools
Funder
National Health and Medical Research Council
Funding Amount
$610,267.00
Summary
Glaucoma is a common cause of loss of vision worldwide but we are unable to predict which people are at high risk of blindness. We aim to discover the genetic risk factors for glaucoma. We will use cutting edge genetic technology to assess the whole genome in thousands of patients with glaucoma. We hope to identify important new glaucoma genes, which could lead to the development of diagnostic tests and treatments which will provide the most cost-efficient ways to prevent glaucoma blindness.
Diatom lipids to reveal sea-ice history in remote Antarctic regions. This project aims to understand seasonal Antarctic sea-ice extent using molecular, geochemical, elemental and genomic characteristics of specific marine phytoplankton (diatoms). Little is known of the seasonal sea-ice variation and the position of the summer sea-ice extent a million years before satellite records, but this information is critical to determining air-sea gas exchange and ecosystem food web regulation. This projec ....Diatom lipids to reveal sea-ice history in remote Antarctic regions. This project aims to understand seasonal Antarctic sea-ice extent using molecular, geochemical, elemental and genomic characteristics of specific marine phytoplankton (diatoms). Little is known of the seasonal sea-ice variation and the position of the summer sea-ice extent a million years before satellite records, but this information is critical to determining air-sea gas exchange and ecosystem food web regulation. This project will unite geochemical and biological approaches to provide the data to improve past Antarctic ecosystem and climate models where sea-ice data is missing. Studying diatom biomarkers in deep sea cores from Australia’s Southern Ocean will redefine knowledge of Antarctic climate and provide data necessary to improve global ecosystem and climate models.Read moreRead less
The genetics of adaptation: changing developmental trajectories in eucalypts. During their life cycles, many animals and plants undergo genetically programmed changes in form. Such changes may be dramatic and rapid as seen in insect metamorphoses or plant heteroblasty, and may have ecological, evolutionary and even economic consequences. The project aims to identify the genes controlling such transitions in Australia's eucalypts.
Powerful knowledge: mapping out standards of teachers' knowledge for teaching mathematics and English to achieve the goals of the curriculum. Setting standards is an important step to raising teacher quality. This project will establish benchmarks for teachers' knowledge at all levels of schooling in two key areas of the curriculum: English and mathematics.
Modelling with data: Advancing STEM in the primary curriculum. Improving the nation's skills in Science, Technology, Engineering, and Mathematics (STEM) remains a continuing concern, especially given the decline in international test results. The project aims to introduce a new approach to promoting this learning across grades 3-6 through modelling with data. With a focus on inquiry processes involving data variation and uncertainty within STEM-based contexts, the project aims to develop the imp ....Modelling with data: Advancing STEM in the primary curriculum. Improving the nation's skills in Science, Technology, Engineering, and Mathematics (STEM) remains a continuing concern, especially given the decline in international test results. The project aims to introduce a new approach to promoting this learning across grades 3-6 through modelling with data. With a focus on inquiry processes involving data variation and uncertainty within STEM-based contexts, the project aims to develop the important mathematical and statistical literacies needed for lifting student achievements. In advancing both theory and practice, the project aims to contribute to knowledge of primary students' capabilities for STEM problem solving and ways of enhancing implementation of the Australian Curriculum.Read moreRead less
Talking Maths: Bridging the gap through talk in Early Years mathematics . The study aims to address the gap in mathematical performance in Australia in relation to socioeconomic status (SES) by focusing on language and learning in mathematics. The study will design and evaluate a school-based intervention that positions language through talk as a key resource in teaching mathematics in Grades 1 and 2. Outcomes of the study will be empirical evidence of the effect of a language-based pedagogy on ....Talking Maths: Bridging the gap through talk in Early Years mathematics . The study aims to address the gap in mathematical performance in Australia in relation to socioeconomic status (SES) by focusing on language and learning in mathematics. The study will design and evaluate a school-based intervention that positions language through talk as a key resource in teaching mathematics in Grades 1 and 2. Outcomes of the study will be empirical evidence of the effect of a language-based pedagogy on young students' achievement in mathematics and further understanding of the relationship between talk and learning. These outcomes will inform policy and teacher education and have a long lasting impact on low SES students' educational and work opportunities with ultimate impact on economic and cultural prosperity.
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The endangered swift parrot as a model for managing small migratory birds. Endangered swift parrots use variable locations while breeding in eastern Tasmania and over winter on the Australian mainland. This project aims to develop effective conservation strategies for swift parrots and other migrants using new and long term data and innovative technological solutions to tracking small birds across vast landscapes.