The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced gen ....The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced genetic engineering, the development of new principles and systems for information storage and transmission, and the design of artificial systems capable of self-referential assembly in other environments.Read moreRead less
Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant ....Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant contributions to the new and evolving priority research area of Bioinformation Science (including bioinformatics). Outcomes will include novel techniques for analysis and mining of post-genome data, with applications to developments in Bio-medicine and Bio-agricultureRead moreRead less
Kingdom switching microbial pathogens: the bioinformatics of mutation in the genomes of viruses and bacteria affecting crops, livestock and people. Some organisms that cause infectious diseases have moved between plants and vertebrates, either recently or repeatedly over evolutionary time. Switching between plants and vertebrates strongly influences the way these microbes mutate and evolve. We will search the genomic sequence databases for information about how the choice of host influences muta ....Kingdom switching microbial pathogens: the bioinformatics of mutation in the genomes of viruses and bacteria affecting crops, livestock and people. Some organisms that cause infectious diseases have moved between plants and vertebrates, either recently or repeatedly over evolutionary time. Switching between plants and vertebrates strongly influences the way these microbes mutate and evolve. We will search the genomic sequence databases for information about how the choice of host influences mutations in viral and bacterial genomes and model the evolutionary processes involved. This project will advance our understanding of the fine structure of microbial genomes and the importance of selection pressures on genes. It will lead to better disease management strategies for humans, and for domestic crops and livestock.Read moreRead less
ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functi ....ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functional materials, ii) high-tech IT/communications/sensing materials, iii) materials solutions for manufacturing, iv) materials for a sustainable Australia, and v) emerging materials technologies. Key programs will promote interdisciplinary workshops and early career researcher interactions.Read moreRead less
Special Research Initiatives - Grant ID: SR0354605
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high per ....The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high performance computing through open sourced middleware. The result will be an unparalleled predictive capacity for complex Earth systems. The outcome will be confidence in the knowledge that underpins our decisions as stakeholders to keep Australia sustainable.Read moreRead less
Nano-machining of diamond-like carbon (DLC): Scientific basis and technical potential. Nanotechnology will be the basis for the next post-industrial revolution, and will be the main driver of future national economies. It is crucially important that at the very least Australia is a significant niche player in those developments. The project represents an effort to promote those goals.
Sustainable processes for next-generation surface coatings and core-shell nanoparticles based on biomolecular templating. Nanotechnology promises new materials with broad impact, yet our ability to manufacture complex nanomaterials using sustainable processes is very limited. This project will advance our knowledge of nanomaterial manufacture using inspiration from how complex materials are made in nature. This project will deliver next-generation surface coatings that are incredibly thin but st ....Sustainable processes for next-generation surface coatings and core-shell nanoparticles based on biomolecular templating. Nanotechnology promises new materials with broad impact, yet our ability to manufacture complex nanomaterials using sustainable processes is very limited. This project will advance our knowledge of nanomaterial manufacture using inspiration from how complex materials are made in nature. This project will deliver next-generation surface coatings that are incredibly thin but strong, and specialised nanoparticles made using biocompatible processes. The knowledge and methods developed will benefit the biotechnology and nanotechnology sectors, as well as research in soft-matter science, quantum computing, photonics and healthcare. The value proposition for innovation in these fields will increasingly rely on new nanomanufacturing approaches.Read moreRead less
The Physics of Network Computation. This project combines expertise in nonlinear soliton physics and computational sciences in order to provide new insights into the physics of network computation. Our proposal addresses the mathematics and computer modelling underlying nonconscious problem solving. We develop a new template concept, the meta-mode, which embodies the network structure of knowledge and the linking mechanisms, which underpin human creativity. We establish the optimal connectiv ....The Physics of Network Computation. This project combines expertise in nonlinear soliton physics and computational sciences in order to provide new insights into the physics of network computation. Our proposal addresses the mathematics and computer modelling underlying nonconscious problem solving. We develop a new template concept, the meta-mode, which embodies the network structure of knowledge and the linking mechanisms, which underpin human creativity. We establish the optimal connectivity distributions to preserve distinct pattern classes yet allow model radical shifts in paradigms, and develop algorithms for autonomous connectivity optimisation. We investigate nonlinear process such as solitons and random Boolean networks as realisations of these principles.Read moreRead less
Ethos and Topos: A Philosophical Investigation of the Ethics and Politics of Place. This project will contribute to the public and academic understanding of the way our sense of place relates to our sense of who we are, and the ethical implications of that relation. The outcomes of the project will have an application to a wide range of applied and policy areas in which questions of identity and belonging are at issue. It will connect directly with ongoing public discussion about a number of cr ....Ethos and Topos: A Philosophical Investigation of the Ethics and Politics of Place. This project will contribute to the public and academic understanding of the way our sense of place relates to our sense of who we are, and the ethical implications of that relation. The outcomes of the project will have an application to a wide range of applied and policy areas in which questions of identity and belonging are at issue. It will connect directly with ongoing public discussion about a number of critical contemporary issues relating to ideas of nationhood and community, our connection to land and environment, and our sense of identity and belonging.Read moreRead less
Uncoupling past salinity and temperature signals in the Indo-Pacific Warm Pool: implications for climate change in the Australian region. The tropical oceans and in particular the Indo-Pacific Warm Pool, immediately to Australia's north, play a key role in modulating global and Australian climate through El-Niño and related phenomena. Using a new microanalysis approach to analyse individual foraminifera from deep-sea cores, we will reconstruct past salinity and temperature variability within the ....Uncoupling past salinity and temperature signals in the Indo-Pacific Warm Pool: implications for climate change in the Australian region. The tropical oceans and in particular the Indo-Pacific Warm Pool, immediately to Australia's north, play a key role in modulating global and Australian climate through El-Niño and related phenomena. Using a new microanalysis approach to analyse individual foraminifera from deep-sea cores, we will reconstruct past salinity and temperature variability within the Warm Pool, and determine changing rainfall patterns and, ENSO and monsoon behaviour under climate conditions that lie outside modern records. This information is vital for understanding past climate and predicting the future intensity and frequency of El-Niño related drought and wet cycles in Australia.Read moreRead less