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Factors associated with the recruitment and retention of the current and future nursing workforce - a longitudinal e-cohort study. The overall effectiveness of the Australian health care system is dependent on a knowledgeable, skilled and viable nursing workforce. Currently there is a critical shortage of qualified nurses actively working in the Australian health care system which limits the capacity of the system to effectively manage an ageing population. The broad aim of this research project ....Factors associated with the recruitment and retention of the current and future nursing workforce - a longitudinal e-cohort study. The overall effectiveness of the Australian health care system is dependent on a knowledgeable, skilled and viable nursing workforce. Currently there is a critical shortage of qualified nurses actively working in the Australian health care system which limits the capacity of the system to effectively manage an ageing population. The broad aim of this research project is to examine factors associated with recruitment and retention of the current and future nursing workforce across metropolitan, regional and rural areas; with a particular focus on work-based injury. In addition, the project will employ smart use of information technology to develop innovative e-cohort techniques.Read moreRead less
Child health and developmental inequities: Evidence for precision policy. The project aims to use cutting edge analytic approaches applied to existing data to identify how policy interventions related to parents’ mental health, preschool programs, and the built environment can be optimised to reduce inequities in children’s mental, academic, and physical health outcomes. The project will be informed by our partners and advisers from across government portfolios and service delivery, ensuring tha ....Child health and developmental inequities: Evidence for precision policy. The project aims to use cutting edge analytic approaches applied to existing data to identify how policy interventions related to parents’ mental health, preschool programs, and the built environment can be optimised to reduce inequities in children’s mental, academic, and physical health outcomes. The project will be informed by our partners and advisers from across government portfolios and service delivery, ensuring that the evidence generated has contemporary policy relevance. The project expects to identify clear and actionable policy pathways to reduce child inequities in Australia, which can benefit decision makers by helping them to direct limited public funds towards intervention opportunities that will have the greatest impact.Read moreRead less
Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not re ....Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not respond to the current TNF treatments. Improved anti-TNF strategies would provide enhanced health outcomes and welcome relief to many Australians. In addition, the economic benefit of the TNF market is very substantial. Therefore the potential impact of this research is very high both for health care and economical potential.Read moreRead less
Recruitment and Retention of the Australian Medical Practitioner Workforce - a Longitudinal Electronic Cohort Study. Identifying and acknowledging the significant personal and professional influences on the career decisions of doctors, including the choice to leave the profession for several years and factors driving the decision to return or not return, will provide not only the major public employers of doctors, but also government, community and private practice groups with reliable current e ....Recruitment and Retention of the Australian Medical Practitioner Workforce - a Longitudinal Electronic Cohort Study. Identifying and acknowledging the significant personal and professional influences on the career decisions of doctors, including the choice to leave the profession for several years and factors driving the decision to return or not return, will provide not only the major public employers of doctors, but also government, community and private practice groups with reliable current evidence to inform medical workforce planning and design, and ensure quality health care. Read moreRead less
Planning female and male vaccination and cervical screening strategies to achieve optimal prevention of HPV-related disease. The findings from this research will inform the development of public health policy on the most cost-effective utilisation of resources for preventing cervical, anogenital and head/neck cancers, and genital warts, in women and men, due to human papillomavirus (HPV). We will evaluate strategies for using emerging screening and vaccine technologies to prevent HPV-related dis ....Planning female and male vaccination and cervical screening strategies to achieve optimal prevention of HPV-related disease. The findings from this research will inform the development of public health policy on the most cost-effective utilisation of resources for preventing cervical, anogenital and head/neck cancers, and genital warts, in women and men, due to human papillomavirus (HPV). We will evaluate strategies for using emerging screening and vaccine technologies to prevent HPV-related disease, and assess potential adverse outcomes of vaccination. Men are currently not covered by routine vaccination or screening programs; this research will assess the benefit to men of vaccinating women only, and will consider the impact of vaccination and other interventions targeted towards men.Read moreRead less
Understanding how local and regional accessibility are associated with active travel, and related health and economic impacts. Exercise and walking are vital for a healthy lifestyle and wellbeing. The accessibility and ’walkability’ of where one lives and works is key to supporting physical activity. Consequently, public health practitioners, urban planners and the transport sector face a common strategic challenge; shifting people from private vehicles to active forms of transport. This project ....Understanding how local and regional accessibility are associated with active travel, and related health and economic impacts. Exercise and walking are vital for a healthy lifestyle and wellbeing. The accessibility and ’walkability’ of where one lives and works is key to supporting physical activity. Consequently, public health practitioners, urban planners and the transport sector face a common strategic challenge; shifting people from private vehicles to active forms of transport. This project aims to model the health and economic impacts of the ease of: walking and cycling within neighbourhoods; and travelling across wider geographical areas on time spent walking and cycling for transport among both adults and children. This project aims to enable the research team to maximise the opportunities the environment provides for both positive health and well-being in Australia.Read moreRead less
Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will ena ....Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will enable science-based guidelines, advancing disease control, local eradication, and regulatory approval for wombats. Our research framework is adaptable to other mange-impacted species, and advance methods and theory for control of treatable disease in wildlife.Read moreRead less
Towards the development of a novel live vaccine for the control of Glässer's disease (Haemophilus parasuis), a globally significant respiratory disease of swine. Respiratory diseases are common in intensively housed pigs, costing the Australian industry millions of dollars in lost production annually. Glässer's is a highly contagious and often fatal respiratory disease of pigs. Antibiotic therapy is expensive and often results in the emergence of antibiotic resistant organisms. There is also a t ....Towards the development of a novel live vaccine for the control of Glässer's disease (Haemophilus parasuis), a globally significant respiratory disease of swine. Respiratory diseases are common in intensively housed pigs, costing the Australian industry millions of dollars in lost production annually. Glässer's is a highly contagious and often fatal respiratory disease of pigs. Antibiotic therapy is expensive and often results in the emergence of antibiotic resistant organisms. There is also a trend to move away from the use of antibiotics in food production animals. Current vaccines are based on inactivated preparations and do not offer a high level of immune protection. Therefore, there is a great need worldwide for a live vaccine for the effective control of Glässer's disease.Read moreRead less
Developing a smart supervisory control system for pan stage operations in sugar factories. This project aims to develop a prototype smart supervisory control system for pan stage crystallisation operations in raw sugar processing. Intelligent systems technologies will be tailored to provide a standardised approach for pan operations by using key process measurements and combining them with the collective expertise and knowledge of pan operators. This project will lead to a significant advance in ....Developing a smart supervisory control system for pan stage operations in sugar factories. This project aims to develop a prototype smart supervisory control system for pan stage crystallisation operations in raw sugar processing. Intelligent systems technologies will be tailored to provide a standardised approach for pan operations by using key process measurements and combining them with the collective expertise and knowledge of pan operators. This project will lead to a significant advance in the development of intelligent systems techniques for industrial applications and provide a better decision making strategy for pan stage operations with the benefit of reduced costs of sugar manufacture and increased profitability of the Australian sugar industry.Read moreRead less
Increasing amphibian immunity to combat disease causing mass extinction. This project aims to increase amphibian survival to combat the devastating chytrid fungus by identifying resistance genes and increasing their frequency in the host population. The project is interdisciplinary and uses targeted genetic manipulation techniques developed for agriculture to improve disease resistance in wildlife for the first time. Expected outcomes include 1) enhanced international collaborations in comparati ....Increasing amphibian immunity to combat disease causing mass extinction. This project aims to increase amphibian survival to combat the devastating chytrid fungus by identifying resistance genes and increasing their frequency in the host population. The project is interdisciplinary and uses targeted genetic manipulation techniques developed for agriculture to improve disease resistance in wildlife for the first time. Expected outcomes include 1) enhanced international collaborations in comparative immunology, 2) a comprehensive understanding of immunity to chytridiomycosis, and 3) disease resistant amphibians. The anticipated benefit is ability to apply the optimal method to improve conservation of wildlife threatened by emerging disease, such as marker assisted selective breeding or genetic engineering.Read moreRead less