Minimising Infection Risks Associated With Water Exposure And With International Travel: Addressing Data Gaps To Improve Policy And Practice
Funder
National Health and Medical Research Council
Funding Amount
$401,361.00
Summary
This project will provide better understanding of health risks associated with two areas of infectious diseases: i) exposure to water, including water recycling and ii) imported infections associated with international travel. Both these issues are highly topical, and new information about exposure risks is important to help guide appropriate preventive advice.
A Cluster RCT Of The Impact Of A Community-based Hygiene And Sanitation Programme On Infection With Intestinal Parasites Following Mass Albendazole Chemotherapy In Timor-Leste
Funder
National Health and Medical Research Council
Funding Amount
$1,178,136.00
Summary
Intestinal parasites cause anaemia, stunting, wasting and poor mental development in childhood, and are related to poverty and poor hygiene. Treatment with antiparasitic drugs cures infections in human hosts, but does not prevent rapid re-infection when people contact a parasite-contaminated environment. We will quantify the impact of a hygiene and sanitation programme that reduces environmental contamination in communities that receive mass treatment with the antiparasitic drug albendazole.
Do Exposures Before Conception Influence The Risk Of Asthma In Offspring?
Funder
National Health and Medical Research Council
Funding Amount
$688,586.00
Summary
Asthma and poor lung function are major causes of public health issues. Emerging evidence suggests adverse exposures even before the conception of a child may cause these conditions. The proposed project is part of an international study across generations to identify these factors. This study will provide novel evidence to guide interventions and identify studies to advance this area further. These original findings will be of great importance both nationally and internationally.
A Randomised, Double Blinded Intervention Study To Assess Health Effects Of Drinking Water From Rainwater Tanks
Funder
National Health and Medical Research Council
Funding Amount
$860,510.00
Summary
We are planning to perform a study in Adelaide to assess if drinking untreated rainwater causes a health risk. Eight years into a drought Australia's water sources are becoming increasingly depleted, so we need to reduce water consumption and consider using alternative sources of water. Increased use of rainwater is one of a number of solutions available. However, current recommendations state that rainwater can be safely used for purposes other than drinking, but because of potential contaminat ....We are planning to perform a study in Adelaide to assess if drinking untreated rainwater causes a health risk. Eight years into a drought Australia's water sources are becoming increasingly depleted, so we need to reduce water consumption and consider using alternative sources of water. Increased use of rainwater is one of a number of solutions available. However, current recommendations state that rainwater can be safely used for purposes other than drinking, but because of potential contamination and limited evidence regarding safety, drinking untreated rainwater is not approved by state health departments. The main outcome of this study will be to determine whether drinking untreated water from rainwater tanks poses a significant health risk. Additionally, we will determine if specific tank or maintenance characteristics can be identified that increase illness risk. The study design consists of following the health of 300 families who drink unboiled rainwater. Families will have a special tap installed that draws water through a water treatment unit (WTU). Half the families will have a working WTU and half will have a sham unit identical in appearance. The functional units sterilise water to remove any microorganisms present, while the sham filters have no effect. All participating families will keep a health diary for one year to record how often they suffer gastroenteritis. Neither the families nor the research workers will know which type of filter has been fitted. Water samples will be collected from selected households. At the end of a year the number of illnesses in the two groups will be compared. If those drinking rainwater from a sham filter suffer more often, then rainwater would be implicated as a source of gastroenteritis. This study will provide health authorities with a better understanding of the relationship between rainwater consumption and human health, and will provide data regarding safe uses of this alternative water source.Read moreRead less
Improving Risk Assessment For Recycled Water: Domestic Laundries And Recreational Parks
Funder
National Health and Medical Research Council
Funding Amount
$81,250.00
Summary
Recent droughts in Australia have meant that recycled water is becoming increasingly important to ensure the sustainability of our water resources. There are four different classes of recycled water (Class A, B, C and D), depending on the level of microbiological contamination. The potential level of exposure of the population to recycled water determines the class of water suitable for various reuse purposes. The need to address water recycling issues in Australia has resulted in increasing num ....Recent droughts in Australia have meant that recycled water is becoming increasingly important to ensure the sustainability of our water resources. There are four different classes of recycled water (Class A, B, C and D), depending on the level of microbiological contamination. The potential level of exposure of the population to recycled water determines the class of water suitable for various reuse purposes. The need to address water recycling issues in Australia has resulted in increasing numbers of innovative recycling schemes such as dual reticulation systems which supply two qualities of water to households, one of high quality for drinking and a second piped system delivering treated recycled water for non-potable (non-drinking) use. In this project, we will investigate the safety of using recycled water in different situations by using water with different known concentrations of micro-organisms to simulate recycled waters of different classes. Most state health authorities in Australia do not approve the use of recycled water for machine washing because of a lack of safety data, but its use in laundries could significantly reduce the need for high quality drinking water. We will perform experiments to help determine the safety of using recycled water for rinsing clothes during a washing machine cycle. Another use of recycled water is for irrigation of recreational parks. Because of safety concerns, when recycled water of Class B or C is used, some states advocate that the public must wait at least 4 hours after watering before they can gain access. This time period may be unnecessary. We will perform experiments to assess the potential exposure to micro-organisms in grass for park users at different time periods following irrigation with water of various classes. The information obtained from this project will help in the decision-making of health and water regulatory agencies.Read moreRead less
Environmental Risk Factors And Genetic Modifiers For Lung Health And Lung Function In A High Risk Cohort
Funder
National Health and Medical Research Council
Funding Amount
$95,348.00
Summary
Asthma is an important determinant of respiratory health and longevity. While early life exposures are thought to be important, the evidence linking them with asthma and lung function is inconclusive. There is a scarcity of longitudinal studies and few investigate genes and environment. This study will determine whether environmental exposures along with their relevant genetic modifiers are related to increased risk of asthma and impaired lung function in a high allergy risk birth cohort.
The Predictors Of Asthma And Lung Function Deficits In The Third Decade: Longitudinal Study Of MACS Sibships
Funder
National Health and Medical Research Council
Funding Amount
$1,176,908.00
Summary
This will be the world’s first birth cohort study to use substantial prospective data to investigate how biological, psychosocial, and environmental markers from birth will predict asthma and lung function in the third decade of life. Our findings will be crucial to the development of new policy and practice for the prevention and management of these conditions and uncover crucial risk factors for young adult asthma.
Defining An Ethical And Evidence-based Approach To Clinical Research In Children And Adolescents With Chronic Kidney Disease (CKD)
Funder
National Health and Medical Research Council
Funding Amount
$84,800.00
Summary
Chronic kidney disease (CKD) in children and adolescents is a serious health condition, which impacts patients' academic abilities and achievement as well as their social wellbeing and their physical and mental health. This study will investigate the range of impacts that CKD has on patients and families, and explore the ways that these problems should best be addressed in future research from the perspective of patients and their families.