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CAN PRIORITY ALLOCATION OF DECEASED DONOR KIDNEYS BASED ON EPLET AND BROAD HLA-ANTIGEN MATCHING IMPROVE KIDNEY TRANSPLANT POTENTIAL, REDUCES IMMUNOGENICITY AND IMPROVE HEALTH OUTCOMES IN INDIGENOUS KIDNEY TRANSPLANT CANDIDATES?
Funder
National Health and Medical Research Council
Funding Amount
$334,472.00
Summary
Although kidney transplantation has been shown to improve life expectancy in patients with chronic kidney disease (CKD), indigenous patients with CKD wait twice as long on the wait-list before transplant and have up to a 3-fold increased risk of rejection and infections resulting in graft loss and death respectively compared to non-indigenous patients. A better understanding of the immunological make-up of indigenous patients may help to reduce the risk of complications and improve survival.
Using An App For Suicide Prevention Amongst Young Indigenous People: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$954,657.00
Summary
Of the many apps now available, a few aim to prevent suicide or improve mental health. None of these has been properly evaluated. Indigenous people under the age of 35 are three to five times more likely to suicide than their non-Indigenous peers and have limited access to suitable support services. This project aims to trial a suicide prevention app designed with and for young indigenous people.
Improving Access To Primary Care For Aboriginal Babies In Western Australia. The ‘Stork’ Population Based Cluster Randomised Trial.
Funder
National Health and Medical Research Council
Funding Amount
$1,300,459.00
Summary
Over 50% of Western Australian Aboriginal babies are still not receiving preventative care in the early months of life. We will undertake a population based trial of a new integrated model of early infant primary care to improve access and health outcomes for young infants especially infants who live in the most disadvantaged and mobile families. Our primary outcome measure is improved hospitalisation rates in infants aged 0-3 months. Results will be used to develop improved primary care models
Do People With Disabilities Access Community-based Palliative Care Services And Does This Service Relieve Hospitals And Emergency Departments: A Study Of The Needs Of People With Intellectual Disability, Multiple Sclerosis And Schizophrenia.
Funder
National Health and Medical Research Council
Funding Amount
$369,208.00
Summary
Very little is know about health service needs and use by people with disabilities at the end of life. The study will help to address this gap. The three groups chosen are adults with an intellectual disability, multiple sclerosis, and/or schizophrenia. The study aims to explore the needs of these people and their carers in their last year of life including the need for palliative care and whether access to palliative care relieves some of the burden on hospital and emergency departments
Understanding The Socio-cultural Dimensions Of Tuberculosis In Papua New Guinea: Knowledge To Optimise Public Health Solutions
Funder
National Health and Medical Research Council
Funding Amount
$727,410.00
Summary
Papua New Guinea has among the highest TB incidence rates in the world, with rates in particular areas considerably higher. This three-year qualitative study will examine the socio-cultural contexts of TB control programs. The project outcome will be better contextualised solutions to improve the effectiveness of TB control programs and therefore the spread of TB and its drug resistant forms.
Host-pathogen Interactions In Clostridial Myonecrosis
Funder
National Health and Medical Research Council
Funding Amount
$577,573.00
Summary
We will analyse the interaction between the bacteria that cause gas gangrene, and the infected host, from both a host and pathogen perspective. We will examine how the host’s response to infection can be modulated to decrease the severity of disease and we will identify the biochemical processes that are essential for bacterial growth in the host, a necessary prerequisite for disease. Outcomes will be a better understanding of the mechanisms of disease causation and improved disease control.
Evidence For Action To Improve The Health Of Urban Aboriginal Children And Adolescents: The SEARCH Study
Funder
National Health and Medical Research Council
Funding Amount
$2,877,467.00
Summary
The proposed project builds on the Study of Environment on Aboriginal Resilience and Child Health (SEARCH), a cohort study of >1600 children and their families based on a long-standing Aboriginal Community Controlled Health Sector and research partnership. The project aims to improve urban Aboriginal child and adolescent health by using data from participants to identify opportunities for intervention and developing data-driven multicomponent interventions to improve health services.
Longitudinal Investigation Of Health Outcomes In Urban Aboriginal Children: SEARCH Follow-up
Funder
National Health and Medical Research Council
Funding Amount
$2,675,557.00
Summary
The government is committed to reducing the gap in Aboriginal health. SEARCH is Australia’s largest prospective longitudinal study of urban Aboriginal children and will provide, for the first time, comprehensive information on the causes of health and illness in a large group of urban Aboriginal children. SEARCH is a partnership with Aboriginal Community Controlled Health Services. SEARCH will identify the factors that can be changed in early childhood to prevent later disease.
Towards An Evidence-based And Equitable Mental Health System For Children In Australia
Funder
National Health and Medical Research Council
Funding Amount
$706,059.00
Summary
Mental health problems in Australian children are common and associated with adverse short and long term outcomes. Treatments including medication and psychological interventions can improve these outcomes but only 50% of Australian children with mental health problems receive them. We will quantify child, family, clinician and health care system factors associated with treatment use and provide a roadmap for clinicians and policy makers to improve access for Australian children.
What Types Of Local Built Environment Synergise With, Or Antagonise The Benefits Of Clinical Management For The Prevention Of Cardiovascular Events Among People With Type 2 Diabetes Mellitus? Longitudinal Analysis Of A Cohort Of 20,765 Australians
Funder
National Health and Medical Research Council
Funding Amount
$704,405.00
Summary
The built environments where people live influences lifestyles and health, as well as whether people in need of healthcare can access relevant services. We will use very large data to examine if the success of clinical management of type 2 diabetes mellitus (T2DM) on sustained lifestyle change and in preventing heart attacks is influenced by local built environment. Results will be translated to practitioners of T2DM management to help promote cardiovascular health.