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Scheme : NHMRC Project Grants
Research Topic : GUIDELINES
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  • Funded Activity

    Computer-assisted Clinical Guidelines For The Management Of Manifestations Of Anxiety, Aggression And Depression

    Funder
    National Health and Medical Research Council
    Funding Amount
    $354,032.00
    Summary
    This project focuses on creating a new approach to integration of clinical guidelines and the development of a computer-assisted tool to support medical reasoning in psychogeriatrics. The primary focus of this research is on helping medical practitioners to better manage dementia patients with symptoms of anxiety, aggression and depression living in nursing homes. It has the potential to fundamentally improve the way guidelines are utilised in clinical practice
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    Funded Activity

    Improving The Care For People With Acute Low Back Pain By Allied Health Professionals: Cluster RCT.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $682,134.00
    Summary
    The project focuses on the NHMRC Clinical Practice Guidelines (CPG) for the management of acute low back pain, and more specifically the key messages of non-referral to x-ray and advising patients to stay active. A mixed design approach will be used in line with the framework for evaluating complex interventions (MRC 2000). A qualitative approach using semi-structured interviews with physiotherapists, chiropractors and the patients of both will be conducted to identify the barriers and enablers .... The project focuses on the NHMRC Clinical Practice Guidelines (CPG) for the management of acute low back pain, and more specifically the key messages of non-referral to x-ray and advising patients to stay active. A mixed design approach will be used in line with the framework for evaluating complex interventions (MRC 2000). A qualitative approach using semi-structured interviews with physiotherapists, chiropractors and the patients of both will be conducted to identify the barriers and enablers to implementation of the evidence-based clinical practice guideline. The interviews will be underpinned by a theoretical framework grounded in behavioural theory. Information from the interviews will be used to develop a survey to canvas views of a larger population of chiropractors and physiotherapists. The results of the interviews and survey will inform the development of a targeted implementation strategy suitable for use in private physiotherapy and chiropractic clinics. Potential interventions include educational strategies, patient and practitioner information via various media, reminder systems and peer leadership. A cluster randomised controlled trial (C-RCT) will then be conducted to determine the effects of the strategy. Practices will be randomised to receive either the developed implementation strategy, including strategies targeted at clinicians and patients, or to a control group receiving access to the guideline alone. The outcomes of the implementation strategy will be assessed at the level of the practitioner (did the strategy result in a change of practice?), and the patient (did the practice change result in improved patient outcomes?). Subgroup analyses will investigate effects specific to chiropractors and physiotherapists.
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    Funded Activity

    Changing Practice Patterns In The Management Of Heart A Ttack

    Funder
    National Health and Medical Research Council
    Funding Amount
    $113,229.00
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    Funded Activity

    Randomised Trial Of A Combined Pill

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,308,548.00
    Summary
    People who have experienced a previous heart attack or stroke are at greatest risk of having another cardiovascular event. Drug treatment, with aspirin and medication to lower blood pressure and cholesterol, has been shown to substantially reduce this risk. Despite good evidence that these drugs are effective, and that their use is recommended in both Australian and international guidelines, many people who should be taking these medications on a long-term basis are not. This may partly be due t .... People who have experienced a previous heart attack or stroke are at greatest risk of having another cardiovascular event. Drug treatment, with aspirin and medication to lower blood pressure and cholesterol, has been shown to substantially reduce this risk. Despite good evidence that these drugs are effective, and that their use is recommended in both Australian and international guidelines, many people who should be taking these medications on a long-term basis are not. This may partly be due to under-prescribing by doctors, but it is also likely that asymptomatic patients are discouraged by the cost and inconvenience of taking many tablets. In the first study of its kind in this country, we will determine whether a strategy based on the provision of recommended treatments in a single pill (a polypill) will result in better use of these drugs, and as a consequence, will achieve optimum practice in patients with heart disease or stroke. Under the care of their general practitioner, 1000 such patients will be randomly allocated to the polypill, or to continuing their usual treatment. At the end of 2 years, both groups will be assessed for the proportion of people still prescribed and taking all recommended treatments. We will also collect information on the attitudes and experiences of those participating in the study of prescribing (by doctors), dispensing (by pharmacists) and taking (by patients) the polypill. As cardiovascular diseases are the leading causes of illness and death in Australia, finding new ways to ensure the maximum use of known, effective preventive treatments in patients with heart disease and stroke, particularly to those who have less access to health care, is of critical importance. The polypill represents a novel strategy with the potential to achieve this objective, and to improve the clinical care and well-being of many thousands of Australians.
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    Funded Activity

    Antenatal Group B Streptococcus Screening: Timing, Dete Ction And Women's Views

    Funder
    National Health and Medical Research Council
    Funding Amount
    $115,207.00
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    Funded Activity

    Inter-Practitioner Variability In The Management Of Colorectal Cancer And Its Impact On Tumour Relapses

    Funder
    National Health and Medical Research Council
    Funding Amount
    $269,108.00
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    Funded Activity

    A Cluster Randomised Controlled Trial Of Nurse And General Practitioner Partnership For Care Of COPD

    Funder
    National Health and Medical Research Council
    Funding Amount
    $449,377.00
    Summary
    Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease that can progress to severe disability and use of hospital services. It is an important cause of both death and disability in Australia. Specifically it is the third leading cause of disease burden after heart disease and stroke. Smoking is the most important cause of the disease and there is strong evidence that smoking cessation will largely prevent progression of COPD. National evidence based guidelines for management of COPD w .... Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease that can progress to severe disability and use of hospital services. It is an important cause of both death and disability in Australia. Specifically it is the third leading cause of disease burden after heart disease and stroke. Smoking is the most important cause of the disease and there is strong evidence that smoking cessation will largely prevent progression of COPD. National evidence based guidelines for management of COPD were published in 2003 but these need to be implemented in the community. General practice is well placed to have a key role in early intervention and evidence based management of COPD. There is evidence that specialised nurses working in collaboration with GPs can improve the care the chronic illnesses including COPD. Care Plans with input from health professionals from a range of disciplines have been recommended for COPD but there are barriers to implementing these in general practice. This project brings together nurse assistance and care planning in a model of care designed to deliver best practice management of COPD in the community. The aim of this research is to evaluate the impact of anurse and GP partnership for care of COPD. We will examine the effect on quality of care and health outcomes at 6 and 12 months follow up. Our hypothesis is that the use of a nurse to work as a team with the patient and GP to develop and implement a care plan based on clinical practice guidelines will improve the quality of care received and have a beneficial effect on the patients' respiratory and overall health. This research will be of major significance for improving COPD care in the community and will have far reaching implications for both policy and practice. It will also define a new role for nurses and GPs working in partnership.
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    Funded Activity

    Difficult Decisions: A Critical Analysis Of Consent To High-risk Medical Procedures

    Funder
    National Health and Medical Research Council
    Funding Amount
    $320,918.00
    Summary
    Consent is the cornerstone of ethics as applied to healthcare and is central to the relationship between healthcare and the law. Whilst no-one would deny the importance of seeking consent to high-risk medical procedures, much depends on the practical manner in which this is done. By studying consent for high-risk procedures with the participation of patients and their health care providers, we will both test the limits of consent and find practical ways to address those limits. In doing so, the .... Consent is the cornerstone of ethics as applied to healthcare and is central to the relationship between healthcare and the law. Whilst no-one would deny the importance of seeking consent to high-risk medical procedures, much depends on the practical manner in which this is done. By studying consent for high-risk procedures with the participation of patients and their health care providers, we will both test the limits of consent and find practical ways to address those limits. In doing so, the project will re-cast consent processes in a way that better accommodates the contingencies of clinical practice in high-risk settings in which patient autonomy is often compromised. Because this reformulation of consent will be grounded in the realities of high-risk clinical practice, our findings will reflect the needs and values of relevant stakeholders (patient and health professionals) and more likely to make a significant contribution to patient care and health policy. This project also addresses what the High Court of Australia has acknowledged as widespread weaknesses in the common formulation of consent in medicine. Finally this project, which operates in an important area of overlap between the law and medicine, will show how these disciplines can work jointly to serve the interests of all Australians, and Australian society.
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    Funded Activity

    Ethical And Legal Issues Surrounding The Decision-making Process For Donating And Banking Umbilical Cord Blood

    Funder
    National Health and Medical Research Council
    Funding Amount
    $417,550.00
    Summary
    Altruistic donation of umbilical cord blood (UCB) is essential to provide a source of stem cells to treat various cancers and blood-immune disorders. However, parents can instead, bank UCB for personal use. This project will determine if parents are aware and understand differences between UCB donation and banking, as well as analysing the legal issues surrounding both processes. We aim to make recommendations to improve the decision-making process with the hope of increasing UCB donation rates.
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    Funded Activity

    Improving Asthma Control: General Practice Strategies To Optimise Medication Adherence

    Funder
    National Health and Medical Research Council
    Funding Amount
    $460,820.00
    Summary
    Asthma is a major health problem for Australia. Many patients have frequent symptoms and need urgent health care because they do not use a preventer inhaler regularly. This may be intentional e.g. fear of side-effects, and-or unintentional e.g. forgetting. This real-life study will test two simple strategies for GPs to improve their patients' use of preventer medications, to improve asthma control. Innovative technology will allow GPs to tailor the approach to each patient during a normal visit.
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