Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlyin ....Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlying biological and biomedical processes, bringing sustainable discovery of new relationships and variations within the data. The project aims to support new approaches to medical diagnosis and treatment, and offer crucial lessons to address the broader challenge of understanding large, complex data sets.Read moreRead less
Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air insi ....Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air inside leaves based on stable isotope analysis of carbon dioxide and water vapour exchanged between leaves and air. The project is expected to provide fundamental knowledge about how stomata regulate photosynthesis and water use, with significant implications for modelling vegetation function and for improving the performance of crop plants.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100001
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Automated Vehicles in Rural and Remote Regions. The Centre will build skills and capability to test and deploy safe, socially acceptable, automated vehicles (AV) for rural, regional and remote Australian public roads, where manufacturing, agriculture, mining and defence industries face significant challenges of driver shortages, rising costs, long distances, rough roads, and environmental impacts. The centre will unite technology providers, regulators, government and end ....ARC Training Centre for Automated Vehicles in Rural and Remote Regions. The Centre will build skills and capability to test and deploy safe, socially acceptable, automated vehicles (AV) for rural, regional and remote Australian public roads, where manufacturing, agriculture, mining and defence industries face significant challenges of driver shortages, rising costs, long distances, rough roads, and environmental impacts. The centre will unite technology providers, regulators, government and end users with world-leading interdisciplinary researchers to create new human-AV systems, datasets, frameworks, case studies, platforms, and a vastly upskilled workforce. This will reduce transport costs, increase capacity, boost supply chain efficiency and resilience, improve road safety, and elevate Australian capability.Read moreRead less
Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Functional links between estuaries and their catchments: How does land use change affect estuarine ecological and bio-geochemical function? Estuaries are iconic recreational areas of high ecological and socio-economic value. Estuarine health is strongly linked to the catchments that feed them, yet we have no detailed understanding of these links. This project will use a number of state of the art approaches to better understand how land use affects estuarine health.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100211
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and developmen ....The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and development using Australian English and facilitate the development of Australian speech technology applications from automatic speech recognition and text-to-speech synthesis used in taxi and other ordering services, to hearing prostheses and talking head aids for learning-impaired children, and a range of security and forensic applications.Read moreRead less
Will stomatal responses to humidity and carbon dioxide constrain tropical forest productivity as atmospheric carbon dioxide rises? This project will investigate two physiological processes that will partly determine growth responses of tropical forest trees to rising atmospheric carbon dioxide. The project will produce equations summarising physiological responses that can be incorporated into process-based models of tropical forest productivity.
Reading the isotopic archive: carbon and oxygen stable isotope ratios as recorders of plant physiological processes. This project will investigate how plant physiological processes are reflected in stable isotope ratios of carbon and oxygen in plant tissues. Results will contribute towards a mechanistic understanding of the processes that cause isotopic modifications, thereby enabling an improved interpretation of naturally occurring stable isotope signals.
Industrial Transformation Training Centres - Grant ID: IC210100019
Funder
Australian Research Council
Funding Amount
$4,583,816.00
Summary
ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective dig ....ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective digital solutions. By developing new capacity and capability to drive the digital transformation of industries supporting our ageing population, our Centre seeks to deliver economic and social benefits that enable Australians to live enriched, healthy and independent lives as they age.Read moreRead less
Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spri ....Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spring-like function of the foot. It will explain a conceptually novel design allowing shoes to support our feet, whilst harnessing the energetic benefits of the foot's spring-like function. This research has the potential to revolutionise athletic footwear design and has direct implications for enhanced performance in running athletes.Read moreRead less